2022
Hypophosphatemia: A Practical Guide to Evaluation and Management
Tebben P. Hypophosphatemia: A Practical Guide to Evaluation and Management. Endocrine Practice 2022, 28: 1091-1099. PMID: 35940468, DOI: 10.1016/j.eprac.2022.07.005.Peer-Reviewed Original ResearchConceptsClinical manifestationsNormal phosphate homeostasisParathyroid hormoneFibroblast growth factorFunction of phosphateRange of symptomsCell membrane integrityEnzyme functionGrowth factorPhosphate balanceSkeletal mineralizationMembrane integrityChronic causesGastrointestinal tractPhosphate homeostasisDiverse rolesEnergy homeostasisHypophosphatemia
2013
Clinical spectrum of hypophosphatasia diagnosed in adults
Berkseth K, Tebben P, Drake M, Hefferan T, Jewison D, Wermers R. Clinical spectrum of hypophosphatasia diagnosed in adults. Bone 2013, 54: 21-27. PMID: 23352924, DOI: 10.1016/j.bone.2013.01.024.Peer-Reviewed Original ResearchConceptsMusculoskeletal painAbsence of genetic testingUrine phosphoethanolamineHistory of fractureAdult hypophosphatasiaHip/femoral neckClinical manifestationsClinical spectrum of hypophosphatasiaSubtrochanteric femur fracturesIncident fracturesLow serum alkaline phosphataseDiagnostic codesIliac crest bone biopsiesAlkaline phosphataseFracture patientsFamily historyConsistent with osteomalaciaEvidence of osteomalaciaInclusion criteriaGenetic testingFemur fracturesMedical recordsSerum alkaline phosphataseSymptomatic subjectsRadiographic chondrocalcinosis
2010
Severe Hypercalcemia due to Primary Hyperparathyroidism with MEN 2A
Thompson G, Dy B, Vazquez B, Tebben P, Kumar S. Severe Hypercalcemia due to Primary Hyperparathyroidism with MEN 2A. World Journal Of Endocrine Surgery 2010, 2: 131-133. DOI: 10.5005/jp-journals-10002-1037.Peer-Reviewed Original ResearchSevere hypercalcemia due to primary hyperparathyroidismHypercalcemia due to primary hyperparathyroidismPrimary hyperparathyroidismSevere hypercalcemiaParathyroid adenomaMEN 2ASurgical managementRare presentation of primary hyperparathyroidismCalcium levelsPresentation of primary hyperparathyroidismDecreased bone mineral densityElevation of serum calciumSingle parathyroid adenomaTreatment of hyperparathyroidismEarly surgical managementBone mineral densityTime of diagnosisParathyroid carcinomaRare presentationClinical presentationSerum calciumMineral densitySevere elevationClinical manifestationsDifferential diagnosis