2018
Integrase inhibitor-based regimens result in more rapid virologic suppression rates among treatment-naïve human immunodeficiency virus–infected patients compared to non-nucleoside and protease inhibitor–based regimens in a real-world clinical setting
Jacobson K, Ogbuagu O. Integrase inhibitor-based regimens result in more rapid virologic suppression rates among treatment-naïve human immunodeficiency virus–infected patients compared to non-nucleoside and protease inhibitor–based regimens in a real-world clinical setting. Medicine 2018, 97: e13016. PMID: 30412140, PMCID: PMC6221636, DOI: 10.1097/md.0000000000013016.Peer-Reviewed Original ResearchConceptsVirologic suppressionInhibitor-based regimensAntiretroviral therapyMedian timeIntegrase strand transfer inhibitor (INSTI) classHuman immunodeficiency virus-infected patientsIntegrase inhibitor-based regimensMedian baseline CD4 countHuman immunodeficiency virus (HIV) patientsRetrospective single-center studyClinical settingProtease inhibitorsReal-world clinical settingART regimen typeVirologic suppression ratesBaseline CD4 countSingle-center studyVirus-infected patientsCells/μLCopies/mLStudy inclusion criteriaNon-nucleoside reverseRoutine clinical settingLower median timeART initiation
2017
Comparison of Time to Viral Suppression Among Treatment-Naïve HIV-Infected Adults Initiating Combination Antiretroviral Therapy by Antiretroviral Regimen Class
Jacobson K, Ogbuagu O. Comparison of Time to Viral Suppression Among Treatment-Naïve HIV-Infected Adults Initiating Combination Antiretroviral Therapy by Antiretroviral Regimen Class. Open Forum Infectious Diseases 2017, 4: s432-s432. PMCID: PMC5630773, DOI: 10.1093/ofid/ofx163.1090.Peer-Reviewed Original ResearchViral suppressionAntiretroviral therapyART initiationMedian timeART regimensHIV patientsRetrospective single-center chart reviewTreatment-naïve HIV patientsSingle-center chart reviewProtease inhibitorsART regimen typeTreatment-naïve HIVCombination antiretroviral therapyBaseline viral loadTreatment of HIVStudy inclusion criteriaNon-nucleoside reverseRoutine clinical settingLower median timeART regimenINSTI regimensNonstandard regimensRegimen typeVirologic suppressionVirologic failure