2020
Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics
Blumental-Perry A, Jobava R, Bederman I, Degar A, Kenche H, Guan B, Pandit K, Perry N, Molyneaux N, Wu J, Prendergas E, Ye Z, Zhang J, Nelson C, Ahangari F, Krokowski D, Guttentag S, Linden P, Townsend D, Miron A, Kang M, Kaminski N, Perry Y, Hatzoglou M. Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics. Communications Biology 2020, 3: 626. PMID: 33127975, PMCID: PMC7603330, DOI: 10.1038/s42003-020-01322-4.Peer-Reviewed Original ResearchConceptsMitochondrial genomeNuclear-encoded genesCell type-specific mannerNon-coding RNASteady-state transcriptionMitochondrial energy metabolismControl regionPositive regulationMitochondrial bioenergeticsMitochondria stressMitochondrial functionSpecific mannerAlveolar epithelial type II cellsEnergy metabolismType II cellsEpithelial type II cellsGenomePhysiological stressRNAII cellsCellsMouse lungTranscriptionGenesMitochondria
2009
Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data
Corcoran DL, Pandit KV, Gordon B, Bhattacharjee A, Kaminski N, Benos PV. Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data. PLOS ONE 2009, 4: e5279. PMID: 19390574, PMCID: PMC2668758, DOI: 10.1371/journal.pone.0005279.Peer-Reviewed Original ResearchConceptsProtein coding genesMiRNA genesCoding genesIntragenic miRNAsPol II chromatin immunoprecipitationNon-coding RNA regulatorsRNA polymerase II promoterChromatin immunoprecipitation dataDiverse biological processesOwn unique promoterPolymerase II promoterTranscription start siteIntergenic miRNAsTranscription regulationMiRNA promotersRNA regulatorsChromatin immunoprecipitationPromoter organizationHost genesPrimary transcriptTranscript organizationStart siteImmunoprecipitation dataUnique promoterBiological processes