2017
Serum Matrix Metalloproteinase-7, Respiratory Symptoms, and Mortality in Community-Dwelling Adults. MESA (Multi-Ethnic Study of Atherosclerosis)
Armstrong HF, Podolanczuk AJ, Barr RG, Oelsner EC, Kawut SM, Hoffman EA, Tracy R, Kaminski N, McClelland RL, Lederer DJ. Serum Matrix Metalloproteinase-7, Respiratory Symptoms, and Mortality in Community-Dwelling Adults. MESA (Multi-Ethnic Study of Atherosclerosis). American Journal Of Respiratory And Critical Care Medicine 2017, 196: 1311-1317. PMID: 28570100, PMCID: PMC5694831, DOI: 10.1164/rccm.201701-0254oc.Peer-Reviewed Original ResearchConceptsInterstitial lung abnormalitiesMatrix metalloproteinase-7Serum MMP-7Serum MMP-7 levelsMMP-7 levelsCommunity-dwelling adultsRespiratory symptomsOutcome dataOdds of ILAMetalloproteinase-7Serum matrix metalloproteinase-7Subclinical interstitial lung diseaseCause mortality ratesIdiopathic pulmonary fibrosisInterstitial lung diseaseLog unit incrementExertional dyspneaCause mortalityLung functionPulmonary fibrosisCox regressionLung diseasePotential confoundersPrognostic biomarkerLung abnormalities
2014
Open-Access Biorepository for Idiopathic Pulmonary Fibrosis. The Way Forward
White ES, Brown KK, Collard HR, Conoscenti CS, Cosgrove GP, Flaherty KR, Leff JA, Martinez FJ, Roman J, Rose D, Violette S, Kaminski N. Open-Access Biorepository for Idiopathic Pulmonary Fibrosis. The Way Forward. Annals Of The American Thoracic Society 2014, 11: 1171-1175. PMID: 25167209, PMCID: PMC4299004, DOI: 10.1513/annalsats.201406-289oi.Peer-Reviewed Original ResearchConceptsIdiopathic pulmonary fibrosisPulmonary fibrosisInvestigator-initiated clinical studyHuman lung diseasesHuman lung tissuePatient-derived samplesLung diseaseLung tissueClinical dataClinical studiesClinical phenotypingOutcome dataLung samplesAnimal modelingStandardized fashionHuman specimensTranslational researchPulmonary researchFibrosisBiorepositoryFuture studiesInvestigational processHuman physiologyCurrent knowledge gapsDifferent studies