2022
Impact of baseline blood pressure on adverse outcomes in Japanese patients with non-valvular atrial fibrillation: the J-RISK AF
Kodani E, Tomita H, Nakai M, Akao M, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Ogawa H, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Miyata H, Okamura T, Sasahara Y, Okumura K, Group F. Impact of baseline blood pressure on adverse outcomes in Japanese patients with non-valvular atrial fibrillation: the J-RISK AF. European Heart Journal Open 2022, 2: oeac081. PMID: 36583077, PMCID: PMC9793850, DOI: 10.1093/ehjopen/oeac081.Peer-Reviewed Original ResearchSystolic baseline blood pressureBaseline blood pressureAtrial fibrillationMajor bleedingHazard ratioAF RegistryJapanese patientsCardiovascular deathIschemic strokeBlood pressureAdverse outcomesBaseline systolic BPNon-valvular AF patientsNon-valvular atrial fibrillationFushimi AF RegistryJ-RHYTHM RegistryIndependent risk factorBaseline BP valuesLarge-scale cohortCause deathAdverse eventsCardiovascular mortalityAF patientsPooled analysisRisk factorsUsefulness of echocardiographic parameters in predicting the incidence of ischemic stroke in Japanese patients with non-valvular atrial fibrillation
Tezuka Y, Akao M, Suzuki S, Yamashita T, Kodani E, Tsuda T, Hayashi K, Furusho H, Sawano M, Fukuda K, Nakai M, Sasahara Y, Miyamoto Y, Tomita H, Okumura K. Usefulness of echocardiographic parameters in predicting the incidence of ischemic stroke in Japanese patients with non-valvular atrial fibrillation. European Heart Journal 2022, 43: ehac544.548. DOI: 10.1093/eurheartj/ehac544.548.Peer-Reviewed Original ResearchIncidence of ISRelative wall thicknessPrescription of OACsCHA2DS2-VASc scoreIschemic strokeLV ejection fractionOral anticoagulantsAtrial fibrillationJapanese patientsNVAF patientsEchocardiographic parametersEjection fractionRisk factorsNon-valvular atrial fibrillation patientsHigher relative wall thicknessNon-valvular atrial fibrillationLV end-diastolic dimensionEcho parametersEnd-diastolic dimensionAtrial fibrillation patientsCo-existing diseasesKaplan-Meier analysisParasternal long-axis viewNovel risk scoreBackground Atrial fibrillation
2021
A Novel Risk Stratification System for Ischemic Stroke in Japanese Patients With Non-Valvular Atrial Fibrillation
Okumura K, Tomita H, Nakai M, Kodani E, Akao M, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Ogawa H, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Miyata H, Okamura T, Sasahara Y, Group F. A Novel Risk Stratification System for Ischemic Stroke in Japanese Patients With Non-Valvular Atrial Fibrillation. Circulation Journal 2021, 85: 1254-1262. PMID: 33762526, DOI: 10.1253/circj.cj-20-1075.Peer-Reviewed Original ResearchConceptsJapanese NVAF patientsIndependent risk factorIschemic strokeNVAF patientsRisk factorsAF RegistryHazard ratioC-statisticJapanese non-valvular atrial fibrillation (NVAF) patientsNon-valvular atrial fibrillation patientsCox hazard proportional analysisNovel risk stratification systemNon-valvular atrial fibrillationLower body mass indexFushimi AF RegistryIschemic stroke eventsJ-RHYTHM RegistryAtrial fibrillation patientsOral anticoagulant treatmentBody mass indexSignificant risk factorsRisk stratification systemType of AFVASc scoreAnticoagulant treatment
2020
Association of decreasing hemoglobin levels with the incidence of acute kidney injury after percutaneous coronary intervention: a prospective multi-center study
Kuno T, Numasawa Y, Mikami T, Niimi N, Sawano M, Kodaira M, Suzuki M, Ueno K, Ueda I, Fukuda K, Kohsaka S. Association of decreasing hemoglobin levels with the incidence of acute kidney injury after percutaneous coronary intervention: a prospective multi-center study. Heart And Vessels 2020, 36: 330-336. PMID: 33034713, DOI: 10.1007/s00380-020-01706-w.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPercutaneous coronary interventionRisk of AKIHemoglobin dropAKI incidenceKidney injuryCoronary interventionHemoglobin levelsProspective multi-center studySerum creatinine levelsMulti-center studyRelative decreaseConsecutive patientsCreatinine levelsIndependent predictorsRisk factorsHemoglobin changeHigh riskAbsolute decreaseLogistic regressionPatientsIncidenceHemoglobinInjuryDlRisk Factors Associated With Ischemic Stroke in Japanese Patients With Nonvalvular Atrial Fibrillation
Okumura K, Tomita H, Nakai M, Kodani E, Akao M, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Ogawa H, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Miyata H, Okamura T, Sasahara Y. Risk Factors Associated With Ischemic Stroke in Japanese Patients With Nonvalvular Atrial Fibrillation. JAMA Network Open 2020, 3: e202881. PMID: 32293685, PMCID: PMC7160687, DOI: 10.1001/jamanetworkopen.2020.2881.Peer-Reviewed Original ResearchConceptsNonvalvular atrial fibrillationFushimi AF RegistryJ-RHYTHM RegistryRisk stratification schemesIschemic strokeAF RegistryBody mass indexRisk factorsAtrial fibrillationJapanese patientsPermanent AFPrevious strokeMass indexShinken DatabaseStratification schemesCox proportional hazards analysisLower body mass indexOral anticoagulant useIndependent risk factorProportional hazards analysisSignificant risk factorsIndividual patient dataValvular AFAnticoagulant useCohort study
2019
Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
Kodaira M, Sawano M, Kuno T, Numasawa Y, Noma S, Suzuki M, Imaeda S, Ueda I, Fukuda K, Kohsaka S. Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study. PLOS ONE 2019, 14: e0223215. PMID: 31618228, PMCID: PMC6795465, DOI: 10.1371/journal.pone.0223215.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overCerebrovascular DisordersFemaleHospital MortalityHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionPeripheral Vascular DiseasesPostoperative HemorrhageRadial ArteryRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexTreatment OutcomeConceptsTransradial coronary interventionAcute coronary syndromePeripheral arterial diseaseCerebrovascular diseaseCoronary interventionVascular diseaseRetrospective multicenter cohort studyAcute coronary syndrome patientsPercutaneous coronary intervention registryMulticenter cohort studyCoronary syndrome patientsCoronary Intervention RegistryIncidence of deathCoronary syndromeCohort studyIntervention RegistryArterial diseaseAdverse outcomesRisk factorsPatient outcomesAccess siteSyndrome patientsHigh riskComplicationsPatients
2017
Characteristics and in-hospital outcomes in young patients presenting with acute coronary syndrome treated by percutaneous coronary intervention
Hirota Y, Sawano M, Numasawa Y, Ueda I, Noma S, Suzuki M, Hayashida K, Yuasa S, Maekawa Y, Kohsaka S, Fukuda K. Characteristics and in-hospital outcomes in young patients presenting with acute coronary syndrome treated by percutaneous coronary intervention. Cardiovascular Intervention And Therapeutics 2017, 33: 154-162. PMID: 28585049, DOI: 10.1007/s12928-017-0471-z.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCoronary artery diseaseMulti-vessel diseaseClassical risk factorsCardiogenic shockYounger patientsACS patientsHospital mortalityCoronary syndromeCulprit lesionRisk factorsFamily historyPremature coronary artery diseaseHigher body mass indexPercutaneous coronary intervention registryConsecutive ACS patientsYoung ACS patientsPrevalence of dyslipidemiaChronic kidney diseasePercutaneous coronary interventionCoronary Intervention RegistryBody mass indexCS presentationLonger life expectancyHospital outcomes