2001
GENE TRANSFER FOR ANGIOGENESIS IN CORONARY ARTERY DISEASE
Laham R, Simons M, Sellke F. GENE TRANSFER FOR ANGIOGENESIS IN CORONARY ARTERY DISEASE. Annual Review Of Medicine 2001, 52: 485-502. PMID: 11160791, DOI: 10.1146/annurev.med.52.1.485.Peer-Reviewed Original ResearchConceptsPromising novel therapeutic strategyAvailable preclinical dataStandard revascularization strategyPeripheral vascular diseaseCoronary artery diseasePreliminary clinical experienceNovel therapeutic strategiesCell-based vectorsRevascularization strategyArtery diseasePreclinical dataVascular diseaseClinical trialsIschemic heartBlood flowTherapeutic strategiesClinical experienceTherapeutic angiogenesisAngiogenesisDelivery modalitiesGene transfer studiesDiseaseGene transfer vectorsPreliminary naturePatients
2000
Therapeutic Angiogenesis
Simons M, Laham R, Post M, Sellke F. Therapeutic Angiogenesis. BioDrugs 2000, 14: 13-20. PMID: 18034552, DOI: 10.2165/00063030-200014010-00002.Peer-Reviewed Original ResearchGrowth factorTherapeutic angiogenesisAdvanced coronary diseaseAdverse effect profileInitial clinical dataRecent clinical experienceBasic fibroblast growth factorQuality of lifeAngiogenic growth factorsFibroblast growth factorCoronary diseaseEffect profileClinical dataPreclinical studiesAnimal modelsClinical experienceNew vasculatureClinical applicationPractical clinical applicationsAngiogenesisBFGFBasic biologyPatientsFactorsSymptoms