Semaphorins in cancer: Biological mechanisms and therapeutic approaches
Rehman M, Tamagnone L. Semaphorins in cancer: Biological mechanisms and therapeutic approaches. Seminars In Cell And Developmental Biology 2012, 24: 179-189. PMID: 23099250, DOI: 10.1016/j.semcdb.2012.10.005.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDisease ProgressionHumansMolecular Targeted TherapyNeoplasmsSemaphorinsSignal TransductionConceptsResponsive cell typesHallmarks of cancerMultiple experimental approachesEpigenetic changesSemaphorin signalsPhysiological processesCell migrationPivotal signalsCell typesReceptor complexCell proliferationSemaphorinsCancer cellsDifferent semaphorinsBiological mechanismsHuman tumorsTumor progressionMultiple alterationsTumor angiogenesisPathwayExperimental approachFamily membersTumor microenvironmentImportant roleCells