2023
Pain management and opioid stewardship in adult cardiac surgery: Joint consensus report of the PeriOperative Quality Initiative and the Enhanced Recovery After Surgery Cardiac Society
Grant M, Chappell D, Gan T, Manning M, Miller T, Brodt J, Workgroup P, Shaw A, Engelman D, Mythen M, Guinn N, Aronson S, Schwartz J, Arora R, Morton-Bailey V, Brudney C, Bennett-Guerrero E, Reddy V, Guzzi L, Brown J, Crisafi C. Pain management and opioid stewardship in adult cardiac surgery: Joint consensus report of the PeriOperative Quality Initiative and the Enhanced Recovery After Surgery Cardiac Society. Journal Of Thoracic And Cardiovascular Surgery 2023, 166: 1695-1706.e2. PMID: 36868931, DOI: 10.1016/j.jtcvs.2023.01.020.Peer-Reviewed Original ResearchConceptsCardiac surgery patientsEnhanced recovery programmeHigh-dose opioidsOpioid stewardshipSurgery patientsPain managementCardiac surgeryNonopioid medicationsProvider educationOpioid prescription practicesCardiac surgery populationOptimal pain managementRole of opioidsAdult cardiac surgeryRegional anesthesia techniquesLevel of evidencePotential side effectsOptimal analgesiaOpioid administrationSurgery populationOpioid usePerioperative carePrescription practicesAnesthesia techniquesConsensus recommendations
2022
Association between enrollment in an enhanced recovery program for colorectal cancer surgery and long‐term recurrence and survival
Zorrilla‐Vaca A, Ripolles‐Melchor J, Abad‐Motos A, Mingu I, Moreno‐Jurado N, Martínez‐Durán F, Pérez‐Martínez I, Abad‐Gurumeta A, FuenMayor‐Varela M, Mena G, Grant M. Association between enrollment in an enhanced recovery program for colorectal cancer surgery and long‐term recurrence and survival. Journal Of Surgical Oncology 2022, 125: 1269-1276. PMID: 35234283, DOI: 10.1002/jso.26836.Peer-Reviewed Original ResearchConceptsColorectal cancer surgeryCancer surgeryOncologic recurrenceColorectal cancerCancer stageCox hazard regression analysisMedian compliance rateSurgical inflammatory responseAdvanced colorectal cancerEnhanced recovery programmeOverall survival rateHazards regression analysisLong-term recurrenceAdvanced cancer stageERAS groupERAS interventionsERAS programOverall survivalMultivariable analysisSubgroup analysisInflammatory responseSurgery programLower riskEnhanced recoveryIntervention studies
2020
Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies
Zorrilla-Vaca A, Mena G, Cata J, Healy R, Grant M. Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies. The American Surgeon 2020, 87: 1444-1451. PMID: 33375852, DOI: 10.1177/0003134820954846.Peer-Reviewed Original ResearchConceptsPostoperative acute kidney injuryAcute kidney injuryObservational studyKidney injuryColorectal surgeryConventional careSystematic reviewHigh-risk patient populationConventional perioperative carePerioperative health careRestrictive fluid administrationEnhanced recovery programmeRisk patient populationEvidence-based measuresHemodynamic goalsPostoperative recoveryERP patientsPerioperative careFluid administrationNephrotoxic agentsPatient populationPooled resultsGreater oddsRecovery programMeta-AnalysisGoal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study
Zorrilla-Vaca A, Mena G, Ripolles-Melchor J, Abad-Motos A, Aldecoa C, Lorente J, Ramirez-Rodriguez J, Grant M. Goal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study. The American Surgeon 2020, 87: 1189-1195. PMID: 33342254, DOI: 10.1177/0003134820973365.Peer-Reviewed Original ResearchConceptsGoal-directed fluid therapyEnhanced recovery programmeAcute kidney injurySurgical site infectionColorectal surgeryPostoperative outcomesFluid therapyPostoperative acute kidney injuryPropensity score-matched analysisComparable baseline demographicsMajor postoperative outcomesAdequate tissue perfusionRates of morbidityHospital stayKidney injuryBaseline demographicsCohort studyConventional careERAS programAnastomotic dehiscenceMajor surgerySite infectionPulmonary edemaMulticenter studyTherapy patientsOpioid-Sparing Cardiac Anesthesia: Secondary Analysis of an Enhanced Recovery Program for Cardiac Surgery.
Grant M, Isada T, Ruzankin P, Gottschalk A, Whitman G, Lawton J, Dodd-O J, Barodka V. Opioid-Sparing Cardiac Anesthesia: Secondary Analysis of an Enhanced Recovery Program for Cardiac Surgery. Anesthesia & Analgesia 2020, 131: 1852-1861. PMID: 32889848, DOI: 10.1213/ane.0000000000005152.Peer-Reviewed Original ResearchConceptsIntraoperative opioid administrationEnhanced recovery programmeOpioid administrationCardiac surgeryNonopioid interventionsPostoperative outcomesNumber of interventionsOpioid patientsSecondary analysisSerratus anterior plane blockMorphine sulfate equivalentsOpioid-sparing strategiesPostoperative pain scoresFuture prospective studiesLength of stayLinear mixed-effects regression modelsMixed-effects regression modelsIntraoperative dexmedetomidineLower opioidPreoperative gabapentinMultimodal analgesiaPain scoresPostoperative complicationsOpioid usePlane block
2017
Is enhanced recovery enough for reducing 30-d readmissions after surgery?
Fabrizio A, Grant M, Siddiqui Z, Alimi Y, Gearhart S, Wu C, Efron J, Wick E. Is enhanced recovery enough for reducing 30-d readmissions after surgery? Journal Of Surgical Research 2017, 217: 45-53. PMID: 28602223, DOI: 10.1016/j.jss.2017.04.007.Peer-Reviewed Original ResearchConceptsEnhanced recovery pathwaySurgical site infectionSite infectionSingle tertiary care centerPostoperative surgical site infectionIndex hospitalization lengthTertiary care centerEnhanced recovery programmeLength of stayTransitions of carePatient care experiencesColorectal surgeryReadmission ratesReduced readmissionsHospitalization lengthRetrospective studyCare transitionsCare centerPatient outcomesReadmissionSymptom monitoringSimilar cohortEnhanced recoveryHome transfersCare experiences