2011
Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease
Burg MM, Soufer A, Lampert R, Collins D, Soufer R. Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease. Molecular Medicine 2011, 17: 495-501. PMID: 21267513, PMCID: PMC3105151, DOI: 10.2119/molmed.2010.00083.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseEndothelin-1Parasympathetic activityArtery diseaseAutonomic contributionsChronic stable coronary artery diseaseStable coronary artery diseaseCholinergic antiinflammatory pathwayLaboratory stressCoronary plaque ruptureEndothelin-1 increaseSignificant odds ratioEndothelial cell functionCardiac eventsEndothelial dysfunctionIndwelling catheterAutonomic factorsSympathetic activityAntiinflammatory pathwayAutonomic influencesAutonomic toneOdds ratioPlaque ruptureParasympathetic withdrawalHemodynamic monitor
2010
Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease
Fernandez AB, Soufer R, Collins D, Soufer A, Ranjbaran H, Burg MM. Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease. Psychosomatic Medicine 2010, 72: 348-353. PMID: 20368479, PMCID: PMC2872076, DOI: 10.1097/psy.0b013e3181d71982.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseET-1 increaseET-1Chronic stable coronary heart diseaseStable coronary heart diseaseMultivariate logistic regression modelET-1 elevationAcute coronary syndromeHistory of diabetesRate-pressure productCoronary artery diseaseEndothelin-1 increaseLogistic regression modelsCoronary syndromeArtery diseaseBeta blockersPotential confoundersPressure productHeart diseasePlaque ruptureBlood samplesPatientsAngry ruminationNitric oxideStress protocol
2006
Mental Stress Ischemia: Characteristics, Pathophysiology, Prognosis and Treatment
Burg M. Mental Stress Ischemia: Characteristics, Pathophysiology, Prognosis and Treatment. 2006, 71-82. DOI: 10.1007/978-88-470-0378-1_5.Peer-Reviewed Original Research
2004
Differential impact of parasympathetic withdrawal to mental stress ischemia as assessed by noninvasive evaluation of myocardial perfusion and/or function
Vashist A, Arrighi J, Lampert R, Burg M, Soufer R. Differential impact of parasympathetic withdrawal to mental stress ischemia as assessed by noninvasive evaluation of myocardial perfusion and/or function. Journal Of Nuclear Cardiology 2004, 11: s21. DOI: 10.1016/j.nuclcard.2004.06.068.Peer-Reviewed Original ResearchChronic coronary artery diseaseRegional LV dysfunctionMyocardial ischemiaParasympathetic withdrawalLV dysfunctionChronic chronic coronary artery diseaseMental stress ischemiaRate-pressure productCoronary artery diseaseGreater parasympathetic withdrawalHigh-frequency powerStress ischemiaArtery diseaseNon-invasive imagingMPI defectsSympathovagal balanceIndividual patientsSPECT-MPIIschemiaMyocardial perfusionNoninvasive evaluationPatientsMental arithmetic taskAutonomic responsesSPECT defects
2001
Day-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activation
Jain D, Joska T, Lee F, Burg M, Lampert R, Zaret B. Day-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activation. Journal Of Nuclear Cardiology 2001, 8: 347-355. PMID: 11391305, DOI: 10.1067/mnc.2001.113517.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseSystolic blood pressureLV ejection fractionLV dysfunctionRate-pressure productBlood pressureAnger recallMS taskHeart rate variabilityAutonomic activationLVEF responseArtery diseaseMental stressSympathetic activationHeart rateSymptomatic coronary artery diseaseRate variabilityAbnormal LVEF responseVentricular function responseChronic stable anginaExercise-induced ischemiaLeft ventricular dysfunctionAdverse prognostic signLF/HFCardiac medications7.44 Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease
Arrighi J, Burg M, Cohen I, Soufer R. 7.44 Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease. Journal Of Nuclear Cardiology 2001, 8: s51. DOI: 10.1016/s1071-3581(01)80621-8.Peer-Reviewed Original Research
2000
Myocardial blood-flow response during mental stress in patients with coronary artery disease
Arrighi J, Burg M, Cohen I, Kao A, Pfau S, Caulin-Glaser T, Zaret B, Soufer R. Myocardial blood-flow response during mental stress in patients with coronary artery disease. The Lancet 2000, 356: 310-311. PMID: 11071190, DOI: 10.1016/s0140-6736(00)02510-1.Peer-Reviewed Original Research
1998
Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease
Soufer R, Bremner J, Arrighi J, Cohen I, Zaret B, Burg M, Goldman-Rakic P. Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 6454-6459. PMID: 9600987, PMCID: PMC27794, DOI: 10.1073/pnas.95.11.6454.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseVisual association cortexSuperior frontal gyrusRight visual association cortexCAD patientsHealthy subjectsPositron emission tomographyMental stressAssociation cortexFrontal gyrusArtery diseaseMyocardial ischemiaAnterior cingulateCentral nervous system effectsCAD patient groupCerebral cortical responsePainless myocardial ischemiaNervous system effectsLeft parietal cortexInferior parietal lobuleMiddle temporal gyrusPatient groupSerial subtraction taskRight thalamusInferior frontal gyrusEffects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease
Jain D, Shaker M, Burg M, Wackers F, Soufer R, Zaret B. Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1314-1322. PMID: 9581726, DOI: 10.1016/s0735-1097(98)00092-8.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionPeripheral vascular resistanceCoronary artery diseaseRate-pressure productStress-induced fallSystolic blood pressureArtery diseaseBlood pressureCardiac outputHeart rateMental stressGroup IHemodynamic variablesAnger recallGroup IIMental stressorsEnd-systolic ventricular elastanceMental stress-induced changesSemisupine bicycle exerciseGroup II patientsComparable increaseDiastolic blood pressureVentricular ejection fractionExercise-induced changesVascular resistance
1995
Prognostic Implications of Mental Stress-Induced Silent Loft Ventricular Dysfunction in Patients With Stable Angina Pectoris
Jain D, Burg M, Soufer R, Zaret B. Prognostic Implications of Mental Stress-Induced Silent Loft Ventricular Dysfunction in Patients With Stable Angina Pectoris. The American Journal Of Cardiology 1995, 76: 31-35. PMID: 7793399, DOI: 10.1016/s0002-9149(99)80796-6.Peer-Reviewed Original ResearchConceptsStable angina pectorisTransient LV dysfunctionAdverse cardiac eventsCardiac eventsLV dysfunctionAngina pectorisMental stressAbnormal cardiovascular reactivityHigher cardiac eventsCohort of patientsCoronary artery diseaseGroup of patientsVentricular function monitoringMental arithmeticVentricular dysfunctionAdverse eventsBaseline characteristicsBeta blockersContinuous ambulatoryArtery diseaseRisk stratificationPrognostic implicationsStress perfusionFunction monitoringHeart rateEjection fraction fall during mental stress in coronary artery disease: Is it due to peripheral effects or contractile dysfunction?
Shaker S, Jain D, Burg M, Wackers F, Soufer R, Zaret B. Ejection fraction fall during mental stress in coronary artery disease: Is it due to peripheral effects or contractile dysfunction? Journal Of Nuclear Cardiology 1995, 2: s27. DOI: 10.1016/s1071-3581(05)80195-3.Peer-Reviewed Original ResearchCoronary artery diseaseArtery diseaseContractile dysfunctionPeripheral effectsMental stressDysfunctionDiseasePrognostic value of mental stress induced silent left ventricular dysfunction in coronary artery disease
Jain D, Burg M, Soufer R, Zaret B. Prognostic value of mental stress induced silent left ventricular dysfunction in coronary artery disease. Journal Of Nuclear Cardiology 1995, 2: s91. DOI: 10.1016/s1071-3581(05)80449-0.Peer-Reviewed Original Research
1993
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease
Burg M, Jain D, Soufer R, Kerns R, Zaret B. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal Of The American College Of Cardiology 1993, 22: 440-448. PMID: 8335813, DOI: 10.1016/0735-1097(93)90048-6.Peer-Reviewed Original ResearchConceptsSilent left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery diseaseVentricular dysfunctionArtery diseaseBlood pressureChronic stable coronary artery diseaseStable coronary artery diseaseStress thallium-201 imagingMental stressGroup I patientsSilent myocardial ischemiaThallium-201 imagingAbsence of symptomsSerial radionuclide ventriculographyStructured interviewsNonischemic groupEjection fractionI patientsPsychological factorsVentricular indexRadionuclide ventriculographyClinical indicesMyocardial ischemiaReversible defects
1987
Social support, type A behavior, and coronary artery disease.
Blumenthal J, Burg M, Barefoot J, Williams R, Haney T, Zimet G. Social support, type A behavior, and coronary artery disease. Psychosomatic Medicine 1987, 49: 331-340. PMID: 3615762, DOI: 10.1097/00006842-198707000-00002.Peer-Reviewed Original ResearchConceptsPerceived Social Support ScaleCoronary artery disease severitySocial supportLong-term health consequencesDiagnostic coronary angiographyCoronary artery diseaseType A structured interviewStructured interviewsSevere CADArtery diseaseCoronary angiographySignificant CADType A behavior patternA behavior patternDisease severityHealth consequencesSocial Support ScaleType BsPsychometric testsSupport ScaleSocial support interactionsLow levelsHigh levelsPatientsAngiography