2014
A Highly Sensitive Europium Nanoparticle-Based Immunoassay for Detection of Influenza A/B Virus Antigen in Clinical Specimens
Zhang P, Vemula SV, Zhao J, Du B, Mohan H, Liu J, Mubarak H, Landry ML, Hewlett I. A Highly Sensitive Europium Nanoparticle-Based Immunoassay for Detection of Influenza A/B Virus Antigen in Clinical Specimens. Journal Of Clinical Microbiology 2014, 52: 4385-4387. PMID: 25297327, PMCID: PMC4313323, DOI: 10.1128/jcm.02635-14.Peer-Reviewed Original Research
2011
Diagnostic tests for influenza infection
Landry ML. Diagnostic tests for influenza infection. Current Opinion In Pediatrics 2011, 23: 91-97. PMID: 21150446, DOI: 10.1097/mop.0b013e328341ebd9.Peer-Reviewed Original ResearchConceptsMolecular testingMultiplex molecular testRapid antigen testInfluenza infectionViral loadAntigen testPatient groupSeasonal influenzaImmunofluorescence testDiagnostic test performanceAntigenic changesNext pandemicRapid cultureDiagnostic testsMolecular testsMarked variabilityNegative resultsSame testDiagnostic methods
2009
Developments in Immunologic Assays for Respiratory Viruses
Landry ML. Developments in Immunologic Assays for Respiratory Viruses. Clinics In Laboratory Medicine 2009, 29: 635-647. PMID: 19892225, DOI: 10.1016/j.cll.2009.07.003.Peer-Reviewed Original Research
2007
Serum IgA Antibodies to Epstein-Barr Virus (EBV) Early Lytic Antigens Are Present in Primary EBV Infection
Bhaduri-McIntosh S, Landry ML, Nikiforow S, Rotenberg M, El-Guindy A, Miller G. Serum IgA Antibodies to Epstein-Barr Virus (EBV) Early Lytic Antigens Are Present in Primary EBV Infection. The Journal Of Infectious Diseases 2007, 195: 483-492. PMID: 17230407, DOI: 10.1086/510916.Peer-Reviewed Original ResearchConceptsPrimary EBV infectionSerum IgA antibodiesIgA antibodiesEBV infectionLytic antigensPrimary infectionPrimary Epstein-Barr virus infectionHealthy EBV-seropositive individualsEpstein-Barr virus infectionEB nuclear antigenEBV-seropositive individualsViral capsid antigenAbsence of antibodiesFlow cytometry-based assayLytic EBV replicationCytometry-based assayBurkitt's lymphoma cellsCapsid antigenMucosal sitesEBV replicationIgM antibodiesVirus infectionInfectionLymphoma cellsSerum samples
2003
Suboptimal Detection of Influenza Virus in Adults by the Directigen Flu A+B Enzyme Immunoassay and Correlation of Results with the Number of Antigen-Positive Cells Detected by Cytospin Immunofluorescence
Landry ML, Ferguson D. Suboptimal Detection of Influenza Virus in Adults by the Directigen Flu A+B Enzyme Immunoassay and Correlation of Results with the Number of Antigen-Positive Cells Detected by Cytospin Immunofluorescence. Journal Of Clinical Microbiology 2003, 41: 3407-3409. PMID: 12843105, PMCID: PMC165325, DOI: 10.1128/jcm.41.7.3407-3409.2003.Peer-Reviewed Original ResearchConceptsVirus infectionEnzyme immunoassayDirectigen FluParainfluenza virus infectionPositive EIA resultsRespiratory syncytial virusAntigen-positive cellsNasopharyngeal swabsSyncytial virusEmergency departmentInfluenza diagnosisDirect immunofluorescenceInfluenza virusVirology laboratoryEIA resultsNight shiftsInfectionInfluenzaImmunofluorescenceFluAdultsVirusCorrelation of resultsImmunoassayCells
2000
A Multisite Trial Comparing Two Cytomegalovirus (CMV) pp65 Antigenemia Test Kits, Biotest CMV Brite and Bartels/Argene CMV Antigenemia
St. George K, Boyd M, Lipson S, Ferguson D, Cartmell G, Falk L, Rinaldo C, Landry M. A Multisite Trial Comparing Two Cytomegalovirus (CMV) pp65 Antigenemia Test Kits, Biotest CMV Brite and Bartels/Argene CMV Antigenemia. Journal Of Clinical Microbiology 2000, 38: 1430-1433. PMID: 10747120, PMCID: PMC86458, DOI: 10.1128/jcm.38.4.1430-1433.2000.Peer-Reviewed Original ResearchConceptsPp65 antigenemiaTransplant recipientsHuman immunodeficiency virus-positive patientsImmunodeficiency virus-positive patientsBone marrow transplant recipientsCMV pp65 antigenemiaOrgan transplant recipientsVirus-positive patientsMarrow transplant recipientsPositive cell countsPeripheral blood leukocytesNegative predictive valueCMV antigenemiaBlood leukocytesAntigenemiaBlood specimensPredictive valueCell countMultisite trialCytomegalovirusStatistical differenceTotalTest kitRecipientsKit2-Hour Cytomegalovirus pp65 Antigenemia Assay for Rapid Quantitation of Cytomegalovirus in Blood Samples
Landry M, Ferguson D. 2-Hour Cytomegalovirus pp65 Antigenemia Assay for Rapid Quantitation of Cytomegalovirus in Blood Samples. Journal Of Clinical Microbiology 2000, 38: 427-428. PMID: 10618133, PMCID: PMC88741, DOI: 10.1128/jcm.38.1.427-428.2000.Peer-Reviewed Original Research
1996
Use of a quantitative cytomegalovirus (CMV) antigenemia test in evaluating HIV+ patients with and without CMV disease.
Wetherill PE, Landry ML, Alcabes P, Friedland G. Use of a quantitative cytomegalovirus (CMV) antigenemia test in evaluating HIV+ patients with and without CMV disease. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1996, 12: 33-7. PMID: 8624758, DOI: 10.1097/00042560-199605010-00005.Peer-Reviewed Original ResearchMeSH KeywordsAdultAIDS-Related Opportunistic InfectionsAntibodies, MonoclonalAntigens, ViralCross-Sectional StudiesCytomegalovirusCytomegalovirus InfectionsCytomegalovirus RetinitisFemaleFluorescent Antibody TechniqueHIV SeropositivityHIV-1HumansLeukocytesMaleMiddle AgedPredictive Value of TestsRetrospective StudiesViral Matrix ProteinsViremiaConceptsCMV antigenemia testCMV diseaseAntigenemia testCMV antigenemiaHIV diseaseCytomegalovirus antigenemia testPositive CMV antigenemiaLife-threatening infectionsDiagnostic techniquesAntigenemia levelsAntigenemia resultsCMV retinitisCytomegalovirus infectionCMV cultureClinical evidenceOphthalmologic examPatientsDiseaseRapid diagnosisAntigenemiaInfectionDiagnosisQuantitative diagnostic techniqueRetinitisHIVEvaluation of CMV Brite kit for detection of cytomegalovirus pp65 antigenemia in peripheral blood leukocytes by immunofluorescence
Landry ML, Ferguson D, Stevens-Ayers T, de Jonge MW, Boeckh M. Evaluation of CMV Brite kit for detection of cytomegalovirus pp65 antigenemia in peripheral blood leukocytes by immunofluorescence. Journal Of Clinical Microbiology 1996, 34: 1337-1339. PMID: 8727936, PMCID: PMC229015, DOI: 10.1128/jcm.34.5.1337-1339.1996.Peer-Reviewed Original Research
1995
Effect of delayed specimen processing on cytomegalovirus antigenemia test results
Landry ML, Ferguson D, Cohen S, Huber K, Wetherill P. Effect of delayed specimen processing on cytomegalovirus antigenemia test results. Journal Of Clinical Microbiology 1995, 33: 257-259. PMID: 7699056, PMCID: PMC227925, DOI: 10.1128/jcm.33.1.257-259.1995.Peer-Reviewed Original Research
1993
Comparison of quantitative cytomegalovirus antigenemia assay with culture methods and correlation with clinical disease
Landry ML, Ferguson D. Comparison of quantitative cytomegalovirus antigenemia assay with culture methods and correlation with clinical disease. Journal Of Clinical Microbiology 1993, 31: 2851-2856. PMID: 8263166, PMCID: PMC266143, DOI: 10.1128/jcm.31.11.2851-2856.1993.Peer-Reviewed Original ResearchConceptsCMV antigenemiaCentrifugation cultureClinical diseaseCMV antigensBlood samplesConventional cultureDetection of cytomegalovirusQuantitative cytomegalovirus antigenemiaHuman immunodeficiency virus-infected patientsBone marrow transplant recipientsCMV antigenemia testHigh-level antigenemiaVirus-infected patientsMarrow transplant recipientsDetection of antigenemiaCulture methodUse of immunofluorescenceAntigenemia testTransplant recipientsCMV infectionCytomegalovirus antigenemiaAntigenemiaIndividual patientsImmunoperoxidase stainingRapid diagnosis
1987
Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining
Zhao LS, Landry ML, Balkovic ES, Hsiung GD. Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining. Journal Of Clinical Microbiology 1987, 25: 1401-1405. PMID: 3040800, PMCID: PMC269234, DOI: 10.1128/jcm.25.8.1401-1405.1987.Peer-Reviewed Original ResearchConceptsHerpes simplex virusSimplex virusCytopathic effectHerpes simplex virus (HSV) isolationMink lungVero cellsOverall isolation rateViral antigen detectionViral infectivity titerCell culturesApplication of immunoperoxidaseCommercial kitsMRC-5 cellsRapidity of detectionRabbit kidney cellsCulture sensitivityVirus isolationClinical specimensInfectious virusInfectivity titersHigh titersAntigen detectionIsolation rateImmunoperoxidaseRabbit kidney
1986
Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells
Landry ML, Zibello TA, Hsiung GD. Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells. Journal Of Clinical Microbiology 1986, 24: 968-971. PMID: 3023442, PMCID: PMC269080, DOI: 10.1128/jcm.24.6.968-971.1986.Peer-Reviewed Original Research