2020
High Agreement Between an Ultrasensitive Clostridioides difficile Toxin Assay and a C. difficile Laboratory Algorithm Utilizing GDH-and-Toxin Enzyme Immunoassays and Cytotoxin Testing
Landry ML, Topal JE, Estis J, Katzenbach P, Nolan N, Sandlund J. High Agreement Between an Ultrasensitive Clostridioides difficile Toxin Assay and a C. difficile Laboratory Algorithm Utilizing GDH-and-Toxin Enzyme Immunoassays and Cytotoxin Testing. Journal Of Clinical Microbiology 2020, 58: 10.1128/jcm.01629-19. PMID: 31776192, PMCID: PMC6989068, DOI: 10.1128/jcm.01629-19.Peer-Reviewed Original ResearchConceptsToxin enzyme immunoassayToxin A/BCell cytotoxicity neutralization assayEnzyme immunoassayStool samplesDifficile toxin assaysProspective clinical studyCytotoxicity neutralization assayCare algorithmChart reviewClinical studiesToxin ACytotoxin testingNeutralization assaysToxin assaysNegative agreementDiscordant samplesLaboratory algorithmTesting algorithmHigh agreementInfection diagnosticsGlutamate dehydrogenasePositive agreementImmunoassayAssays
2003
Suboptimal Detection of Influenza Virus in Adults by the Directigen Flu A+B Enzyme Immunoassay and Correlation of Results with the Number of Antigen-Positive Cells Detected by Cytospin Immunofluorescence
Landry ML, Ferguson D. Suboptimal Detection of Influenza Virus in Adults by the Directigen Flu A+B Enzyme Immunoassay and Correlation of Results with the Number of Antigen-Positive Cells Detected by Cytospin Immunofluorescence. Journal Of Clinical Microbiology 2003, 41: 3407-3409. PMID: 12843105, PMCID: PMC165325, DOI: 10.1128/jcm.41.7.3407-3409.2003.Peer-Reviewed Original ResearchConceptsVirus infectionEnzyme immunoassayDirectigen FluParainfluenza virus infectionPositive EIA resultsRespiratory syncytial virusAntigen-positive cellsNasopharyngeal swabsSyncytial virusEmergency departmentInfluenza diagnosisDirect immunofluorescenceInfluenza virusVirology laboratoryEIA resultsNight shiftsInfectionInfluenzaImmunofluorescenceFluAdultsVirusCorrelation of resultsImmunoassayCells
2001
Evaluation of Biosite Triage Clostridium difficile Panel for Rapid Detection of Clostridium difficile in Stool Samples
Landry M, Topal J, Ferguson D, Giudetti D, Tang Y. Evaluation of Biosite Triage Clostridium difficile Panel for Rapid Detection of Clostridium difficile in Stool Samples. Journal Of Clinical Microbiology 2001, 39: 1855-1858. PMID: 11326003, PMCID: PMC88038, DOI: 10.1128/jcm.39.5.1855-1858.2001.Peer-Reviewed Original ResearchConceptsNegative predictive valuePositive predictive valueCommon antigenStool samplesPredictive valueC. difficile toxin AHigh negative predictive valueAntigen-positive patientsDifficile-negative patientsAntigen positive resultDifficile toxin ADifficile carriersContact precautionsAntibiotic treatmentToxin ACytotoxin titersTriage PanelUnnecessary useClostridium difficilePatients
1987
Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining
Zhao LS, Landry ML, Balkovic ES, Hsiung GD. Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining. Journal Of Clinical Microbiology 1987, 25: 1401-1405. PMID: 3040800, PMCID: PMC269234, DOI: 10.1128/jcm.25.8.1401-1405.1987.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, ViralCell LineCells, CulturedCytopathogenic Effect, ViralHumansImmunoenzyme TechniquesReagent Kits, DiagnosticSimplexvirusVero CellsViral Plaque AssayConceptsHerpes simplex virusSimplex virusCytopathic effectHerpes simplex virus (HSV) isolationMink lungVero cellsOverall isolation rateViral antigen detectionViral infectivity titerCell culturesApplication of immunoperoxidaseCommercial kitsMRC-5 cellsRapidity of detectionRabbit kidney cellsCulture sensitivityVirus isolationClinical specimensInfectious virusInfectivity titersHigh titersAntigen detectionIsolation rateImmunoperoxidaseRabbit kidney
1986
Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells
Landry ML, Zibello TA, Hsiung GD. Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells. Journal Of Clinical Microbiology 1986, 24: 968-971. PMID: 3023442, PMCID: PMC269080, DOI: 10.1128/jcm.24.6.968-971.1986.Peer-Reviewed Original Research
1984
Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections
Hsiung GD, Landry ML, Mayo DR, Fong C. Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections. Clinics In Dermatology 1984, 2: 67-82. PMID: 6100717, DOI: 10.1016/0738-081x(84)90067-1.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, ViralCells, CulturedCytopathogenic Effect, ViralDNA Restriction EnzymesFluorescent Antibody TechniqueHerpes GenitalisHerpes LabialisHerpes SimplexHumansImmunoenzyme TechniquesInclusion Bodies, ViralMicroscopy, ElectronNucleic Acid HybridizationSimplexvirusSpecimen HandlingVirionConceptsHerpes simplex virusHSV infectionHSV-2Virus isolationRecurrence of diseaseCommon viral infectionsEffective antiviral therapyType 2 infectionHerpes simplex virus type 1Simplex virus type 1HSV-1 infectionVirus type 1Fever blistersHSV isolationHerpetic lesionsAntiviral therapyClinical findingsGenital lesionsCommon manifestationDrug reactionsAllergic reactionsSevere diseaseGenital areaSimplex virusInfection results