2013
Comparison of Simplexa HSV 1 & 2 PCR with Culture, Immunofluorescence, and Laboratory-Developed TaqMan PCR for Detection of Herpes Simplex Virus in Swab Specimens
Gitman MR, Ferguson D, Landry ML. Comparison of Simplexa HSV 1 & 2 PCR with Culture, Immunofluorescence, and Laboratory-Developed TaqMan PCR for Detection of Herpes Simplex Virus in Swab Specimens. Journal Of Clinical Microbiology 2013, 51: 3765-3769. PMID: 24006008, PMCID: PMC3889765, DOI: 10.1128/jcm.01413-13.Peer-Reviewed Original ResearchAdolescentAdultAgedAged, 80 and overChildChild, PreschoolClinical Laboratory TechniquesCosts and Cost AnalysisFemaleFluorescent Antibody TechniqueHerpes SimplexHumansInfantInfant, NewbornMaleMiddle AgedPolymerase Chain ReactionSensitivity and SpecificitySimplexvirusTime FactorsVirus CultivationYoung Adult
1997
Detection of herpes simplex virus in clinical specimens by cytospin-enhanced direct immunofluorescence
Landry ML, Ferguson D, Wlochowski J. Detection of herpes simplex virus in clinical specimens by cytospin-enhanced direct immunofluorescence. Journal Of Clinical Microbiology 1997, 35: 302-304. PMID: 8968933, PMCID: PMC229564, DOI: 10.1128/jcm.35.1.302-304.1997.Peer-Reviewed Original Research
1992
Herpes Simplex Types 1 and 2: Latency in the Genital Tract of Guinea Pigs
Landry M, Bull C. Herpes Simplex Types 1 and 2: Latency in the Genital Tract of Guinea Pigs. Intervirology 1992, 33: 204-210. PMID: 1326498, DOI: 10.1159/000150252.Peer-Reviewed Original ResearchMeSH KeywordsAcyclovirAnimalsFemaleGangliaGenitalia, FemaleGuinea PigsHerpes SimplexSimplexvirusSpinal CordRecurrent Genital Infection in the Guinea Pig: Differences between Herpes Simplex Types 1 and 2
Landry M, Myerson D, Bull C. Recurrent Genital Infection in the Guinea Pig: Differences between Herpes Simplex Types 1 and 2. Intervirology 1992, 34: 169-179. PMID: 1339184, DOI: 10.1159/000150279.Peer-Reviewed Original ResearchConceptsHSV-2 strainsHSV-2HSV-1Genital infectionRecurrence rateHSV-1 McKrae strainType 1Herpes simplex virus type 2Simplex virus type 2Recurrent genital infectionsHerpes simplex type 1Guinea pig modelHSV type 1Simplex type 1HSV-1 strainsVirus type 2Vaginal virusAcute infectionLesion recurrenceOcular infectionsMcKrae strainGenital tractNervous systemType 2Guinea pigs
1991
Antiviral Activity of 5-Iodo-2’-Deoxyuridine and Related Drugs in Human Keratinocytes Infected in vitro with Herpes simplex Virus Type 1
Reuveni H, Bull CO, Landry ML, Milstone LM, Schwartz PM. Antiviral Activity of 5-Iodo-2’-Deoxyuridine and Related Drugs in Human Keratinocytes Infected in vitro with Herpes simplex Virus Type 1. Skin Pharmacology And Physiology 1991, 4: 291-297. PMID: 1665069, DOI: 10.1159/000210964.Peer-Reviewed Original ResearchConceptsGuinea pig embryo cellsHerpes simplex virus type 1Simplex virus type 1Virus type 1Antiviral activityThymidine phosphorylaseHuman keratinocytesType 1Cutaneous viral infectionsTopical antiviral agentsAntiviral agentsViral infectionExperimental animalsEmbryo cellsRelated drugsIUdRInfected cellsKeratinocytesDrugsCellsActivityInfectionPhosphorylase
1988
Ability of Herpes Simplex Virus (HSV) Types 1 and 2 To Induce Clinical Disease and Establish Latency Following Previous Genital Infection with the Heterologous HSV Type
Landry M, Zibello T. Ability of Herpes Simplex Virus (HSV) Types 1 and 2 To Induce Clinical Disease and Establish Latency Following Previous Genital Infection with the Heterologous HSV Type. The Journal Of Infectious Diseases 1988, 158: 1220-1226. PMID: 2848899, DOI: 10.1093/infdis/158.6.1220.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCervix UteriFemaleGangliaGuinea PigsHerpes GenitalisRecurrenceSimplexvirusSpinal CordVaginaConceptsHerpes simplex virus type 1Simplex virus type 1Virus type 1Clinical diseaseHSV typesSuperinfecting virusType 1Heterologous virus typesPrevious genital infectionsLevels of serumHSV antibodiesGenital infectionHSV-2Prior infectionLatent infectionHSV-1Type 2Months postinoculationGuinea pigsVirus typeInitial virusLatent virusSuperinfectionInfectionDisease
1987
Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining
Zhao LS, Landry ML, Balkovic ES, Hsiung GD. Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining. Journal Of Clinical Microbiology 1987, 25: 1401-1405. PMID: 3040800, PMCID: PMC269234, DOI: 10.1128/jcm.25.8.1401-1405.1987.Peer-Reviewed Original ResearchConceptsHerpes simplex virusSimplex virusCytopathic effectHerpes simplex virus (HSV) isolationMink lungVero cellsOverall isolation rateViral antigen detectionViral infectivity titerCell culturesApplication of immunoperoxidaseCommercial kitsMRC-5 cellsRapidity of detectionRabbit kidney cellsCulture sensitivityVirus isolationClinical specimensInfectious virusInfectivity titersHigh titersAntigen detectionIsolation rateImmunoperoxidaseRabbit kidney
1986
Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells
Landry ML, Zibello TA, Hsiung GD. Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells. Journal Of Clinical Microbiology 1986, 24: 968-971. PMID: 3023442, PMCID: PMC269080, DOI: 10.1128/jcm.24.6.968-971.1986.Peer-Reviewed Original Research
1985
Comparison of Four Methods for Typing Low-Passage Herpes Simplex Virus Isolates
Mayo D, Hilliard J, Landry M, Egbertson S, Mirkovic R. Comparison of Four Methods for Typing Low-Passage Herpes Simplex Virus Isolates. Intervirology 1985, 23: 112-115. PMID: 2984142, DOI: 10.1159/000149593.Peer-Reviewed Original ResearchConceptsHerpes simplex virusGuinea pig embryo cellsHerpes simplex virus isolatesHSV type 1Direct fluorescent antibody techniqueFluorescent antibody techniqueSimplex virusType 2Clinical isolatesEmbryo cellsType 1Virology laboratoryContinuous cell linesBVDU sensitivityMonoclonal antibodiesChick embryo cellsAntibody techniqueVirus isolatesRestriction endonuclease analysisCell linesIsolatesEndonuclease analysisTyping systemCells
1984
Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections
Hsiung GD, Landry ML, Mayo DR, Fong C. Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections. Clinics In Dermatology 1984, 2: 67-82. PMID: 6100717, DOI: 10.1016/0738-081x(84)90067-1.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, ViralCells, CulturedCytopathogenic Effect, ViralDNA Restriction EnzymesFluorescent Antibody TechniqueHerpes GenitalisHerpes LabialisHerpes SimplexHumansImmunoenzyme TechniquesInclusion Bodies, ViralMicroscopy, ElectronNucleic Acid HybridizationSimplexvirusSpecimen HandlingVirionConceptsHerpes simplex virusHSV infectionHSV-2Virus isolationRecurrence of diseaseCommon viral infectionsEffective antiviral therapyType 2 infectionHerpes simplex virus type 1Simplex virus type 1HSV-1 infectionVirus type 1Fever blistersHSV isolationHerpetic lesionsAntiviral therapyClinical findingsGenital lesionsCommon manifestationDrug reactionsAllergic reactionsSevere diseaseGenital areaSimplex virusInfection resultsGenital Herpes: Pathogenesis and Chemotherapy in the Guinea Pig Model
Hsiung G, Mayo D, Lucia H, Landry M. Genital Herpes: Pathogenesis and Chemotherapy in the Guinea Pig Model. Clinical Infectious Diseases 1984, 6: 33-50. PMID: 6324317, DOI: 10.1093/clinids/6.1.33.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornDisease Models, AnimalFemaleGuinea PigsHerpes GenitalisMaleSimplexvirusConceptsGuinea pig modelGenital herpesAnimal modelsPig modelHuman infectionsNatural historyCommon venereal diseaseRecurrent genital diseaseEffect of immunosuppressionHerpes simplex virusIndividual host responsesNeonatal herpesHerpes infectionPathologic featuresGenital diseaseSimplex virusAntiviral drugsLatent infectionNervous systemHost responseHerpesLow dosesGuinea pigsInfectionDisease
1983
Herpes simplex encephalitis: analysis of a cluster of cases by restriction endonuclease mapping of virus isolates.
Landry M, Berkovits N, Summers W, Booss J, Hsiung G, Summers W. Herpes simplex encephalitis: analysis of a cluster of cases by restriction endonuclease mapping of virus isolates. Neurology 1983, 33: 831-5. PMID: 6306505, DOI: 10.1212/wnl.33.7.831.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgedDNA, ViralEncephalitisEndonucleasesFemaleHerpes SimplexHumansMaleSimplexvirus
1982
Effect of acyclovir on genital infection with herpes simplex virus types 1 and 2 in the guinea pig
Landry M, Lucia H, Hsiung GD, Pronovost A, Dann P, August M, Mayo D. Effect of acyclovir on genital infection with herpes simplex virus types 1 and 2 in the guinea pig. The American Journal Of Medicine 1982, 73: 143-150. PMID: 6285705, DOI: 10.1016/0002-9343(82)90080-8.Peer-Reviewed Original ResearchConceptsHSV-2 infectionHerpes simplex virus type 1Simplex virus type 1Genital infectionVirus type 1Lumbosacral gangliaHSV-2Clinical diseaseLatent infectionHSV-1Guinea pigsHSV-1-infected animalsHSV-2-infected animalsType 1Herpes simplex virus type 2Simplex virus type 2Acyclovir-treated groupEffect of acyclovirHSV-1 strainsVirus type 2Systemic treatmentAcute infectionMild diseaseSpinal cordChronic changes