2020
Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients
Gaston DC, Malinis M, Osborn R, Peaper DR, Landry M, Juthani-Mehta M, Azar MM. Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients. American Journal Of Transplantation 2020, 21: 1304-1311. PMID: 33043603, PMCID: PMC7675520, DOI: 10.1111/ajt.16357.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsOrgan transplant recipientsClinical implicationsCycle threshold valuesSOT patientsTransplant recipientsSymptom onsetYale New Haven Health SystemUpper respiratory tract samplesSARS-CoV-2 viral RNASARS-CoV-2 viral dynamicsAdult SOT recipientsRetrospective chart reviewRespiratory tract samplesSARS-CoV-2 cycle threshold valuesInfection prevention measuresCOVID-19 severityViral RNAHigher clinical acuityPrimary diagnostic testRT-PCR assaysSOT recipientsChart reviewViral loadAdmission severity
2017
Graft loss among renal-transplant recipients with early reduction of immunosuppression for BK viremia
Azar MM, Assi R, Valika AK, Banach DB, Hall IE, Landry ML, Malinis MF. Graft loss among renal-transplant recipients with early reduction of immunosuppression for BK viremia. World Journal Of Transplantation 2017, 7: 269-275. PMID: 29104861, PMCID: PMC5661124, DOI: 10.5500/wjt.v7.i5.269.Peer-Reviewed Original ResearchRenal transplant recipientsGraft lossBK viremiaImmunosuppression reductionAcute rejectionEarly reductionTransplant recipientsPolymerase chain reactionCopies/Death-censored graft lossDeceased donor kidney transplantationKidney transplant recipientsDonor kidney transplantationRenal transplant biopsiesCopies/mLQuantitative polymerase chain reactionGraft functionKidney transplantationTransplant biopsiesMedian ageMonths 1PyVANBKV DNALower incidenceRetrospective analysisFatal case of cutaneous‐sparing orolaryngeal zoster in a renal transplant recipient
Helou E, Grant M, Landry M, Wu X, Morrow JS, Malinis MF. Fatal case of cutaneous‐sparing orolaryngeal zoster in a renal transplant recipient. Transplant Infectious Disease 2017, 19 PMID: 28401625, DOI: 10.1111/tid.12704.Peer-Reviewed Case Reports and Technical NotesConceptsTransplant recipientsHerpes zosterSolid organ transplant recipientsCTLA-4 inhibitorsKidney transplant recipientsRenal transplant recipientsOrgan transplant recipientsAcute rejectionSOT recipientsMucosal lesionsMeningo-encephalitisPoor outcomeFatal casesHerpesvirus infectionSignificant causeRecipientsZosterPneumonitisMorbidityPatientsLesionsInfectionMortalityCases
2013
Hepatitis E virus infection in a liver transplant recipient: delayed diagnosis due to variable performance of serologic assays
Yoo N, Bernstein J, Caldwell C, Dong C, Drobeniuc J, Kamili S, Landry ML. Hepatitis E virus infection in a liver transplant recipient: delayed diagnosis due to variable performance of serologic assays. Transplant Infectious Disease 2013, 15: e166-e168. PMID: 23701647, DOI: 10.1111/tid.12096.Peer-Reviewed Original Research
2000
A Multisite Trial Comparing Two Cytomegalovirus (CMV) pp65 Antigenemia Test Kits, Biotest CMV Brite and Bartels/Argene CMV Antigenemia
St. George K, Boyd M, Lipson S, Ferguson D, Cartmell G, Falk L, Rinaldo C, Landry M. A Multisite Trial Comparing Two Cytomegalovirus (CMV) pp65 Antigenemia Test Kits, Biotest CMV Brite and Bartels/Argene CMV Antigenemia. Journal Of Clinical Microbiology 2000, 38: 1430-1433. PMID: 10747120, PMCID: PMC86458, DOI: 10.1128/jcm.38.4.1430-1433.2000.Peer-Reviewed Original ResearchConceptsPp65 antigenemiaTransplant recipientsHuman immunodeficiency virus-positive patientsImmunodeficiency virus-positive patientsBone marrow transplant recipientsCMV pp65 antigenemiaOrgan transplant recipientsVirus-positive patientsMarrow transplant recipientsPositive cell countsPeripheral blood leukocytesNegative predictive valueCMV antigenemiaBlood leukocytesAntigenemiaBlood specimensPredictive valueCell countMultisite trialCytomegalovirusStatistical differenceTotalTest kitRecipientsKit
1993
Comparison of quantitative cytomegalovirus antigenemia assay with culture methods and correlation with clinical disease
Landry ML, Ferguson D. Comparison of quantitative cytomegalovirus antigenemia assay with culture methods and correlation with clinical disease. Journal Of Clinical Microbiology 1993, 31: 2851-2856. PMID: 8263166, PMCID: PMC266143, DOI: 10.1128/jcm.31.11.2851-2856.1993.Peer-Reviewed Original ResearchConceptsCMV antigenemiaCentrifugation cultureClinical diseaseCMV antigensBlood samplesConventional cultureDetection of cytomegalovirusQuantitative cytomegalovirus antigenemiaHuman immunodeficiency virus-infected patientsBone marrow transplant recipientsCMV antigenemia testHigh-level antigenemiaVirus-infected patientsMarrow transplant recipientsDetection of antigenemiaCulture methodUse of immunofluorescenceAntigenemia testTransplant recipientsCMV infectionCytomegalovirus antigenemiaAntigenemiaIndividual patientsImmunoperoxidase stainingRapid diagnosis
1987
Disseminated adenovirus infection in an immunocompromised host Pitfalls in diagnosis
Landry M, Fong C, Neddermann K, Solomon L, Hsiung GD. Disseminated adenovirus infection in an immunocompromised host Pitfalls in diagnosis. The American Journal Of Medicine 1987, 83: 555-559. PMID: 2821806, DOI: 10.1016/0002-9343(87)90770-4.Peer-Reviewed Original ResearchConceptsBone marrow transplant recipientsAdenovirus infectionPostmortem serum samplesDisseminated adenovirus infectionMarrow transplant recipientsMicroscopic examinationSmall bowel tissueSpecific viral diagnosisLight microscopic examinationOral ulcerationTransplant recipientsCytomegalovirus infectionLaboratory featuresComplement fixation testIll patientsBowel tissueElectron microscopic examinationDiagnostic pitfallsType 2Fatal gastroenteritisLiver tissueIntranuclear inclusionsViral diagnosisSerum samplesColon contents