Marc Vittoria, MD/PhD

I'm Marc, a PGY-1 in internal medicine who ultimately will be training in Heme/Onc as a part of the phsyician-scientist program. Originally an organic chemist in undergrad, I transitioned into cancer cell biology for my PhD. In Neil Ganem's lab we discovered that loss of the Hippo Pathway potently potentiates melanocyte transformation into melanoma even in the absence of oncogenic BRAF signaling as well as what miRNA permit whole-genome doubled cancer cells to escape arrest. Along the way I was fortunate enough to help out with multiple projects ranging from finding new kinases that mediate Hippo pathway signaling (Sanghee Lim's work), what controls cell fate following mitotic slippage (Amanda Bolgioni's work), and finding ways to selectively target whole-genome doubled cancer cells (Ryan Quinton's work).