2022
Trends in the prevalence of vision impairment among the oldest-old Chinese population from 1998 to 2018.
Luo Y, Zhang Q, Han L, Shen Z, Chen Y, Wang K, Huang Z, De Fries CM, Cao G, Su H, Xu H, Chen Z, Ren Z, Hu Y, Xu B. Trends in the prevalence of vision impairment among the oldest-old Chinese population from 1998 to 2018. Journal Of Global Health 2022, 12: 11006. PMID: 35862489, DOI: 10.7189/jogh.12.11006.Peer-Reviewed Original ResearchConceptsOldest-old Chinese populationImpairment prevalenceVision impairmentChinese populationChronic conditionsHealth behaviorsHearing impairmentChinese Longitudinal Healthy Longevity SurveyProminent public health issueSociodemographic variablesRetrospective longitudinal studyPublic health issueLandolt C chartStudy entryChronic diseasesPrevalence trendsChinese adultsLongevity SurveyCognitive impairmentPrevalence changesPrevalenceUrban residenceOlder peopleHealth issuesImpairment
2020
Multimorbidity among Two Million Adults in China
Wang X, Yao S, Wang M, Cao G, Chen Z, Huang Z, Wu Y, Han L, Xu B, Hu Y. Multimorbidity among Two Million Adults in China. International Journal Of Environmental Research And Public Health 2020, 17: 3395. PMID: 32414117, PMCID: PMC7277827, DOI: 10.3390/ijerph17103395.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseCerebrovascular diseaseMultimorbidity patternsMultimorbidity prevalenceBeijing Medical Claim DataMedical claims dataMiddle-aged groupOlder Chinese individualsMillion adultsMorbidity treatmentOlder patientsRheumatoid arthritisPreventive careHeart diseaseChronic diseasesClaims dataHypertensionOlder groupOlder adultsStrong associationDiseaseCOPDMultimorbidityChinese individualsAppropriate guidelines
2019
Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study
Yao SS, Cao GY, Han L, Chen ZS, Huang ZT, Gong P, Hu Y, Xu B. Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study. The Journals Of Gerontology Series A 2019, 75: 1974-1980. PMID: 31406983, DOI: 10.1093/gerona/glz185.Peer-Reviewed Original ResearchConceptsPatterns of multimorbidityPrevalence of multimorbidityMultimorbidity patternsRetirement Longitudinal StudyOlder ChineseChina HealthPopulation-based studyDemographic characteristicsIndividual chronic diseasesLongitudinal studyCommon multimorbidity patternsLogistic regression modelsParticipants' demographic characteristicsNationally Representative SampleEntire cohortPotential confoundersChronic diseasesRepresentative sampleMultimorbidityAlcohol consumptionMemory-related diseasesUrban-rural differencesPrevalenceInterventional implicationsResidential regionThe Epidemiology of Patient‐Reported Hypersomnia in Persons With Advanced Age
Miner B, Gill TM, Yaggi HK, Redeker NS, Van Ness PH, Han L, Fragoso C. The Epidemiology of Patient‐Reported Hypersomnia in Persons With Advanced Age. Journal Of The American Geriatrics Society 2019, 67: 2545-2552. PMID: 31390046, PMCID: PMC6898735, DOI: 10.1111/jgs.16107.Peer-Reviewed Original ResearchConceptsSelf-reported sleep-disordered breathingRestless legs syndromeMean ESS scoreCommunity-dwelling personsESS scoreCross-sectional associationsAdvanced ageHypersomnia symptomsCentral nervous system depressant medicationsEpworth Sleepiness Scale scoreMini-Mental State Examination scoreEpidemiologic Studies-Depression scoreSelf-reported medical conditionsEpidemiology of patientsLow physical activitySleep-disordered breathingBody mass indexPhysical Activity ScalePrecipitating Events ProjectState Examination scoreInsomnia Severity IndexMultivariable regression modelsDepressant medicationsClinical characteristicsCross-sectional design
2018
Insomnia in Community‐Living Persons with Advanced Age
Miner B, Gill TM, Yaggi HK, Redeker NS, Van Ness PH, Han L, Fragoso CAV. Insomnia in Community‐Living Persons with Advanced Age. Journal Of The American Geriatrics Society 2018, 66: 1592-1597. PMID: 29785710, PMCID: PMC6167156, DOI: 10.1111/jgs.15414.Peer-Reviewed Original ResearchConceptsSelf-reported sleep-disordered breathingRestless legs syndromeInsomnia Severity IndexDepressive symptomsBaseline characteristicsOlder adultsCognitive impairmentAverage baseline characteristicsEpidemiology of insomniaChronic lung diseaseSleep-disordered breathingMultivariable regression modelsHigh medical burdenCurrent smokersLegs syndromeLung diseaseClinical correlatesDaytime sleepinessSleep disturbancesAdvanced ageMedical burdenMild severityCardiovascular diseaseDiagnostic confirmationHigh prevalenceDisability Prior to Death Among the Oldest-Old in China
Liu Z, Han L, Wang X, Feng Q, Gill TM. Disability Prior to Death Among the Oldest-Old in China. The Journals Of Gerontology Series A 2018, 73: 1701-1707. PMID: 29408957, PMCID: PMC6230206, DOI: 10.1093/gerona/gly010.Peer-Reviewed Original Research
2017
Distressing Symptoms, Disability, and Hospice Services at the End of Life: Prospective Cohort Study
Gill TM, Han L, Leo‐Summers L, Gahbauer EA, Allore HG. Distressing Symptoms, Disability, and Hospice Services at the End of Life: Prospective Cohort Study. Journal Of The American Geriatrics Society 2017, 66: 41-47. PMID: 28895118, PMCID: PMC5777867, DOI: 10.1111/jgs.15041.Peer-Reviewed Original ResearchConceptsProspective cohort studyEnd of lifeHospice admissionCohort studyDistressing symptomsHospice servicesMonths of lifeNumber of disabilitiesMedian durationSubsequent admissionHigh burdenMedicare claimsAdditional disabilitiesAdmissionAdditional monthsSymptomsOlder personsHospiceMonthly interviewsMonthsDisabilityShort durationAdditional strategiesDurationNew Haven
2013
Dynamics of functional aging based on latent-class trajectories of activities of daily living
Han L, Allore H, Murphy T, Gill T, Peduzzi P, Lin H. Dynamics of functional aging based on latent-class trajectories of activities of daily living. Annals Of Epidemiology 2013, 23: 87-92. PMID: 23305692, PMCID: PMC3558979, DOI: 10.1016/j.annepidem.2012.11.010.Peer-Reviewed Original ResearchConceptsDaily livingFunctional agingCommunity-living adultsEquation Poisson modelsMost older adultsADL disabilityHigher disabilityPersistent disabilitySubstantial morbidityInstrumental ADLADL independenceDisability trajectoriesLatent class trajectoriesCumulative burdenRestricted activityLow burdenSevere disabilityMorbidityPredominant trajectoriesOlder adultsDisabilityTime trendsFunctional autonomyADLGrowth mixture models
2011
Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods
Han L, Kim N, Brandt C, Allore HG. Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods. Annals Of Epidemiology 2011, 22: 9-16. PMID: 22037381, PMCID: PMC4054866, DOI: 10.1016/j.annepidem.2011.10.004.Peer-Reviewed Original ResearchConceptsDepression-related diagnosisAntidepressant useDepression symptomsOlder personsPropensity scoreHopkins Verbal Learning TestHypertensive menAntidepressant medicationIndication biasVerbal Learning TestMedical recordsPotential confoundingCumulative exposureOlder menCognitive impairmentMemory deficitsCognitive deficitsMultiple linear regressionLinear regressionLearning TestApparent associationScoresSymptomsDiagnosisIndications
2002
Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia
Cole MG, McCusker J, Dendukuri N, Han L. Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia. Journal Of Neuropsychiatry 2002, 14: 167-175. PMID: 11983791, DOI: 10.1176/jnp.14.2.167.Peer-Reviewed Original Research