2009
Different Biological Processes Are Associated with Prognosis and Chemotherapy Sensitivity in the Different Molecular Subtypes of Breast Cancer.
Iwamoto T, Iwamoto T, Bianchini G, Coutant C, Shiang C, Matsuoka J, Symmans W, Hortobagyi G, Simon R, Pusztai L. Different Biological Processes Are Associated with Prognosis and Chemotherapy Sensitivity in the Different Molecular Subtypes of Breast Cancer. Cancer Research 2009, 69: 6124-6124. DOI: 10.1158/0008-5472.sabcs-09-6124.Peer-Reviewed Original ResearchER- cancersDifferent molecular subtypesChemotherapy sensitivityChemotherapy responseBreast cancerMolecular subtypesMeta-AnalysisPrognostic pathwaysCohort of patientsPlasma cell functionT cell differentiationNeoadjuvant therapySeparate cohortImmune functionPrognosisGlycolipid metabolismPredictive gene setsBlood vessel formationDifferent subtypesCancerCancer ResOxidative stressCell functionSubtypesVessel formation
2005
A single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding
Symmans W, Fiterman D, Anderson S, Ayers M, Rouzier R, Dunmire V, Stec J, Valero V, Sneige N, Albarracin C, Wu Y, Ross J, Wagner P, Theriault R, Arun B, Kuerer H, Hess K, Zhang W, Hortobagyi G, Pusztai L. A single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding. Endocrine Related Cancer 2005, 12: 1059-1069. PMID: 16322343, DOI: 10.1677/erc.1.01051.Peer-Reviewed Original ResearchConceptsReal-time reverse transcription-polymerase chain reactionInvasive breast cancerImmature cell typesBreast cancerPrimary invasive breast cancerHigh-grade breast cancerMultivariate linear regression analysisReverse transcription-polymerase chain reactionCell typesTranscription-polymerase chain reactionShorter lifetime durationGene expressionParous womenClinicopathologic characteristicsEstrogen receptorHispanic ethnicitySeparate cohortHispanic womenElevated gene expressionLinear regression analysisLifetime historyYounger ageNeu receptorCancerBreastfeeding