2013
Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation
Rajbhandari P, Schalper KA, Solodin NM, Ellison-Zelski SJ, Ping Lu K, Rimm DL, Alarid ET. Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation. Oncogene 2013, 33: 1438-1447. PMID: 23542176, PMCID: PMC3815749, DOI: 10.1038/onc.2013.78.Peer-Reviewed Original ResearchConceptsERα protein levelsERα proteinBreast cancerERα-positive breast cancerProtein levelsPotential surrogate markerRetrospective cohortSurrogate markerBreast carcinomaTherapy decisionsERα levelsESR1 levelsERα ubiquitinationCertain tumorsHuman tumorsDiscordant levelsESR1Pin1 levelsReceptor interactionUbiquitin-proteasome pathwayReceptor degradationImportant biomarkerTumorsCancerTransactivation function
2007
Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential
Retamal MA, Schalper KA, Shoji KF, Bennett MV, Sáez JC. Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 8322-8327. PMID: 17494739, PMCID: PMC1895948, DOI: 10.1073/pnas.0702456104.Peer-Reviewed Original Research