2019
Trends in Performance and Opportunities for Improvement on a Composite Measure of Acute Myocardial Infarction Care
Desai NR, Udell JA, Wang Y, Spatz ES, Dharmarajan K, Ahmad T, Julien HM, Annapureddy A, Goyal A, de Lemos JA, Masoudi FA, Bhatt DL, Minges KE, Krumholz HM, Curtis JP. Trends in Performance and Opportunities for Improvement on a Composite Measure of Acute Myocardial Infarction Care. Circulation Cardiovascular Quality And Outcomes 2019, 12: e004983. PMID: 30871375, DOI: 10.1161/circoutcomes.118.004983.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiology Service, HospitalFemaleGuideline AdherenceHealthcare DisparitiesHumansMaleMiddle AgedMyocardial InfarctionOutcome and Process Assessment, Health CarePractice Guidelines as TopicQuality ImprovementQuality Indicators, Health CareRacial GroupsRegistriesSex FactorsSocioeconomic FactorsTreatment OutcomeUnited StatesConceptsProportion of patientsAcute myocardial infarctionDefect-free careHispanic patientsAMI careOlder patientsCare measuresNational Cardiovascular Data Registry Acute Coronary TreatmentIntervention Outcomes Network RegistryAcute myocardial infarction careGuideline-recommended pharmacotherapyMedicaid insurance coverageSociodemographic groupsMyocardial infarction careSafety-net statusGreatest absolute improvementComposite measureQuality of careHospital-level performanceCessation counselingEvidence-based processReperfusion therapyCardiac rehabilitationCoronary TreatmentVentricular function
2017
Predicting death after acute myocardial infarction
Castro-Dominguez Y, Dharmarajan K, McNamara RL. Predicting death after acute myocardial infarction. Trends In Cardiovascular Medicine 2017, 28: 102-109. PMID: 28826668, DOI: 10.1016/j.tcm.2017.07.011.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionRisk factorsClinical presentation characteristicsRisk stratification modelImportant risk factorPatients important informationPatient riskClinical informationStratification modelPresentation characteristicsMortalityInfarctionRiskHospitalizationPrognosisCliniciansRegional variation in hospitalisation and mortality in heart failure: comparison of England and Lombardy using multistate modelling
Bottle A, Ventura CM, Dharmarajan K, Aylin P, Ieva F, Paganoni AM. Regional variation in hospitalisation and mortality in heart failure: comparison of England and Lombardy using multistate modelling. Health Care Management Science 2017, 21: 292-304. PMID: 28755175, DOI: 10.1007/s10729-017-9410-x.Peer-Reviewed Original ResearchConceptsHeart failureClinical practice differencesMedium-term mortalityHospital administrative databaseSerious chronic conditionsNon-hospital settingsSet of patientsHF admissionsCommon comorbiditiesFirst admissionLondon patientsDeath RegisterHigh morbidityChronic conditionsAdministrative databasesDisease progressionPatientsLower mortalityMortalityAdmissionPractice differencesShort stayLong stayHealthcare systemHospitalisationSex Differences in Trajectories of Risk After Rehospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia
Dreyer RP, Dharmarajan K, Hsieh AF, Welsh J, Qin L, Krumholz HM. Sex Differences in Trajectories of Risk After Rehospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003271. PMID: 28506980, PMCID: PMC5650228, DOI: 10.1161/circoutcomes.116.003271.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionHeart failureReadmission riskDaily riskImmediate postdischarge periodRisk of rehospitalizationSex differencesDeath 1 yearPrincipal discharge diagnosisHospitalization of patientsAssociation of sexRehospitalization riskPostdischarge periodDischarge diagnosisMedicare patientsHigh riskMortality riskMedicare feeTrajectories of riskRehospitalizationInfarctionService beneficiariesHospitalizationPneumoniaSex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial Infarction
Dreyer RP, Dharmarajan K, Kennedy KF, Jones PG, Vaccarino V, Murugiah K, Nuti SV, Smolderen KG, Buchanan DM, Spertus JA, Krumholz HM. Sex Differences in 1-Year All-Cause Rehospitalization in Patients After Acute Myocardial Infarction. Circulation 2017, 135: 521-531. PMID: 28153989, PMCID: PMC5312975, DOI: 10.1161/circulationaha.116.024993.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAge-sex interactionHigh riskRehospitalization ratesClinical factorsMyocardial infarctionCox proportional hazards modelSignificant age-sex interactionCause rehospitalization rateSex differencesMedical record abstractionProportional hazards modelYears of ageFirst yearTRIUMPH studyCause rehospitalizationRecord abstractionPatient interviewsRehospitalizationUS CentersHazards modelPsychosocial factorsPhysician panelHealth statusPsychosocial state
2014
National Trends in Recurrent AMI Hospitalizations 1 Year After Acute Myocardial Infarction in Medicare Beneficiaries: 1999–2010
Chaudhry SI, Khan RF, Chen J, Dharmarajan K, Dodson JA, Masoudi FA, Wang Y, Krumholz HM. National Trends in Recurrent AMI Hospitalizations 1 Year After Acute Myocardial Infarction in Medicare Beneficiaries: 1999–2010. Journal Of The American Heart Association 2014, 3: e001197. PMID: 25249298, PMCID: PMC4323804, DOI: 10.1161/jaha.114.001197.Peer-Reviewed Original Research
2013
Most Important Outcomes Research Papers on Cardiovascular Disease in Women
Gupta A, Lampropulos JF, Bikdeli B, Mody P, Chen R, Kulkarni VT, Dharmarajan K. Most Important Outcomes Research Papers on Cardiovascular Disease in Women. Circulation Cardiovascular Quality And Outcomes 2013, 6: e1-e7. PMID: 23322810, DOI: 10.1161/circoutcomes.112.970202.Peer-Reviewed Original Research