RANKL induces heterogeneous DC‐STAMPlo and DC‐STAMPhi osteoclast precursors of which the DC‐STAMPlo precursors are the master fusogens
Mensah KA, Ritchlin CT, Schwarz EM. RANKL induces heterogeneous DC‐STAMPlo and DC‐STAMPhi osteoclast precursors of which the DC‐STAMPlo precursors are the master fusogens. Journal Of Cellular Physiology 2009, 223: 76-83. PMID: 20039274, PMCID: PMC2814997, DOI: 10.1002/jcp.22012.Peer-Reviewed Original ResearchMeSH KeywordsAcid PhosphataseAnimalsAntigens, CDBiomarkersBlotting, WesternBone Marrow CellsCD47 AntigenCell DifferentiationCell FusionCells, CulturedFlow CytometryImmunoproliferative DisordersIsoenzymesMacrophagesMembrane GlycoproteinsMembrane ProteinsMiceMice, Inbred C57BLMicroscopy, FluorescenceNerve Tissue ProteinsOsteoclastsPhenotypeProtein MultimerizationRANK LigandReverse Transcriptase Polymerase Chain ReactionRNA, MessengerStem CellsTartrate-Resistant Acid PhosphataseTetraspanin 29Time FactorsConceptsOC precursorsDC-STAMPFlow cytometryUnique surface markersMetabolic bone diseaseRANKL-induced osteoclastogenesis