2023
Association Between Mental Health Burden, Clinical Presentation, and Outcomes in Individuals With Symptomatic Peripheral Artery Disease: A Scientific Statement From the American Heart Association
Smolderen K, Samaan Z, Decker C, Collins T, Lazar R, Itoga N, Mena-Hurtado C, Research O. Association Between Mental Health Burden, Clinical Presentation, and Outcomes in Individuals With Symptomatic Peripheral Artery Disease: A Scientific Statement From the American Heart Association. Circulation 2023, 148: 1511-1528. PMID: 37781785, DOI: 10.1161/cir.0000000000001178.Peer-Reviewed Original ResearchMeSH KeywordsAmerican Heart AssociationComorbidityHumansMental HealthPeripheral Arterial DiseaseRisk FactorsConceptsPsychological interventionsPeripheral artery diseaseMental healthStress reduction interventionsSymptomatic peripheral artery diseaseComorbid mental health conditionsMental health concernsRole of painMental health conditionsMental health burdenPAD careCognitive declineBehavioral health needsArtery diseaseCognitive dysfunctionPsychotropic interventionScientific statementPAD treatmentBehavior changeUse of opioidsAmerican Heart AssociationUse of benzodiazepinesChronic disease managementHealth behaviorsFragmentation of care
2022
The Yale Roadmap for Health Psychology and Integrated Cardiovascular Care
Gaffey AE, Harris KM, Mena-Hurtado C, Sinha R, Jacoby DL, Smolderen KG. The Yale Roadmap for Health Psychology and Integrated Cardiovascular Care. Health Psychology 2022, 41: 779-791. PMID: 35201804, DOI: 10.1037/hea0001152.Peer-Reviewed Original ResearchConceptsCardiovascular careCardiovascular diseaseHealth care systemRisk factorsBehavioural risk factor managementTraditional atherosclerotic risk factorsWagner's Chronic Care ModelCare systemAtherosclerotic risk factorsRisk factor managementChronic Care ModelCause of morbidityMental health burdenBehavioral risk factorsChronic cardiovascular diseaseHigh-intensity careAdverse health outcomesMental health disordersHealth psychologyEvidence-based approachComplex multimorbidityRisk patientsCardiovascular populationFactor managementChronic diseases
2021
Increasing Prevalence of Critical Limb Ischemia Hospitalizations With Distinct Mental Health Burden Among Younger Adults
Harris KM, Mena-Hurtado C, Arham A, Burg MM, Freedland KE, Sinha R, Alabi O, Smolderen KG. Increasing Prevalence of Critical Limb Ischemia Hospitalizations With Distinct Mental Health Burden Among Younger Adults. Journal Of The American College Of Cardiology 2021, 78: 2126-2128. PMID: 34794693, DOI: 10.1016/j.jacc.2021.09.025.Peer-Reviewed Original Research
2018
Effectiveness of a comprehensive interactive eHealth intervention on patient-reported and clinical outcomes in patients with an implantable cardioverter defibrillator [ACQUIRE-ICD trial]: study protocol of a national Danish randomised controlled trial
Pedersen SS, Skovbakke SJ, Wiil UK, Schmidt T, dePont Christensen R, Brandt CJ, Sørensen J, Vinther M, Larroudé CE, Melchior TM, Riahi S, Smolderen KGE, Spertus JA, Johansen JB, Nielsen JC. Effectiveness of a comprehensive interactive eHealth intervention on patient-reported and clinical outcomes in patients with an implantable cardioverter defibrillator [ACQUIRE-ICD trial]: study protocol of a national Danish randomised controlled trial. BMC Cardiovascular Disorders 2018, 18: 136. PMID: 29969990, PMCID: PMC6029360, DOI: 10.1186/s12872-018-0872-7.Peer-Reviewed Original ResearchMeSH KeywordsDefibrillators, ImplantableDenmarkElectric CountershockHealth StatusHeart FailureHumansMental HealthMulticenter Studies as TopicPatient Reported Outcome MeasuresPredictive Value of TestsProspective StudiesQuality of LifeRandomized Controlled Trials as TopicRemote Sensing TechnologyRisk FactorsTelemedicineTelemetryTime FactorsTreatment OutcomeConceptsImplantable cardioverter defibrillatorQuality of lifeEHealth interventionsUsual careClinical outcomesCardioverter defibrillatorFlorida Patient Acceptance SurveyCardiac synchronization therapyFirst ICD therapyTrial registrationThe trialCare innovationsManagement of patientsPatient-reported outcomesFirst‐time implantable cardioverter defibrillatorsMonitoring of symptomsQuality of carePatient-physician interactionFirst hospitalisationICD therapyPrimary endpointSecondary endpointsMore patientsSuperiority trialDisease management approachClinical effectiveness
2017
Sex differences in disease-specific health status measures in patients with symptomatic peripheral artery disease: Data from the PORTRAIT study
Roumia M, Aronow HD, Soukas P, Gosch K, Smolderen KG, Spertus JA, Abbott JD. Sex differences in disease-specific health status measures in patients with symptomatic peripheral artery disease: Data from the PORTRAIT study. Vascular Medicine 2017, 22: 103-109. PMID: 28429659, DOI: 10.1177/1358863x16686408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnkle Brachial IndexAustraliaChi-Square DistributionCost of IllnessFemaleHealth Status DisparitiesHealth Status IndicatorsHumansIntermittent ClaudicationLinear ModelsLogistic ModelsMaleMental HealthMiddle AgedMultivariate AnalysisNetherlandsPatient SatisfactionPeripheral Arterial DiseasePrognosisProspective StudiesQuality of LifeRisk FactorsSeverity of Illness IndexSex FactorsSocial BehaviorSocioeconomic FactorsSurveys and QuestionnairesUnited StatesConceptsPeripheral artery diseasePeripheral Artery QuestionnaireHealth statusArtery diseaseSymptoms of PADAnkle-brachial index valuesPAD-specific health statusSymptomatic peripheral artery diseaseDisease-specific health status measuresPAQ scoresPeripheral arterial diseaseSex differencesHealth status domainsInternational prospective studyPoor health statusHealth status measuresMultivariable linear regressionLower PAQ scoresBaseline characteristicsClinical characteristicsPAD symptomsTreatment satisfactionArterial diseaseProspective studyFemale sexDepression Treatment and 1-Year Mortality After Acute Myocardial Infarction
Smolderen KG, Buchanan DM, Gosch K, Whooley M, Chan PS, Vaccarino V, Parashar S, Shah AJ, Ho PM, Spertus JA. Depression Treatment and 1-Year Mortality After Acute Myocardial Infarction. Circulation 2017, 135: 1681-1689. PMID: 28209727, PMCID: PMC5796757, DOI: 10.1161/circulationaha.116.025140.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntidepressive AgentsCause of DeathDepressionFemaleHealth StatusHumansKaplan-Meier EstimateMaleMental HealthMiddle AgedMyocardial InfarctionProportional Hazards ModelsProspective StudiesPsychiatric Status Rating ScalesQuality of LifeRegistriesRisk AssessmentRisk FactorsSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionPatient Health Questionnaire-9Untreated depressionMyocardial infarctionObservational multicenter cohort studyMulticenter cohort studyOne-year mortalityLong-term mortalityPrognosis of patientsPHQ-9 scoresTreatment of depressionPHQ-9 criteriaAMI severityPHQ scoresTRIUMPH studyCohort studyClinical factorsDepression treatmentDischarge diagnosisQuestionnaire-9Medical recordsAMI admissionsPatientsBetter outcomesMortality rate
2015
One Year Health Status Benefits Following Treatment for New Onset or Exacerbation of Peripheral Arterial Disease Symptoms: The Importance of Patients' Baseline Health Status
van Zitteren M, Denollet J, Heyligers JM, Elshof JW, Nooren MJ, Burger DH, de Fijter WM, Vriens PW, Smolderen KG. One Year Health Status Benefits Following Treatment for New Onset or Exacerbation of Peripheral Arterial Disease Symptoms: The Importance of Patients' Baseline Health Status. European Journal Of Vascular And Endovascular Surgery 2015, 50: 213-222. PMID: 26036809, DOI: 10.1016/j.ejvs.2015.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAgedDisease ProgressionFemaleHealth StatusHealth Status IndicatorsHumansLinear ModelsMaleMental HealthMiddle AgedNetherlandsPeripheral Arterial DiseasePredictive Value of TestsPropensity ScoreProspective StudiesRecovery of FunctionRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUltrasonography, Doppler, DuplexConceptsHealth status scoresPeripheral arterial diseaseHealth status gainsBaseline health statusInvasive treatmentStatus scoreHealth statusPatient's baseline health statusPeripheral arterial disease symptomsHealth status levelsHealth status outcomesNew onsetPAD symptomsVascular clinicArterial diseaseHighest quartilePCS scoresInvasive strategyTreatment strategiesClinical informationStatus outcomesPatientsLinear regression analysisChange scoresExacerbationGender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis
Dreyer RP, Smolderen KG, Strait KM, Beltrame JF, Lichtman JH, Lorenze NP, D’Onofrio G, Bueno H, Krumholz HM, Spertus JA. Gender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis. European Heart Journal Acute Cardiovascular Care 2015, 5: 43-54. PMID: 25681487, PMCID: PMC4658311, DOI: 10.1177/2048872615568967.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPrior coronary artery diseaseCoronary artery diseaseHealth statusMyocardial infarctionYounger patientsArtery diseaseCoronary artery disease historyDisease-specific health statusAcute myocardial infarction patientsAggressive symptom controlCornerstone of careWorse physical functionBaseline health statusMedical record abstractionVisual analog scaleHealth status outcomesMyocardial infarction patientsDisease-specific measuresMean health scoresLogistic regression analysisQuality of lifeHealth status informationGender differencesSymptom control
2014
Gender Differences in Health Status and Adverse Outcomes Among Patients With Peripheral Arterial Disease
Dreyer RP, van Zitteren M, Beltrame JF, Fitridge R, Denollet J, Vriens PW, Spertus JA, Smolderen KG. Gender Differences in Health Status and Adverse Outcomes Among Patients With Peripheral Arterial Disease. Journal Of The American Heart Association 2014, 4: e000863. PMID: 25537275, PMCID: PMC4330046, DOI: 10.1161/jaha.114.000863.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmbulatory Care FacilitiesCohort StudiesFemaleFollow-Up StudiesHealth StatusHealth Status IndicatorsHumansMaleMental HealthMiddle AgedMultivariate AnalysisNetherlandsPeripheral Arterial DiseasePhysical FitnessProportional Hazards ModelsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSex FactorsSurvival AnalysisTime FactorsConceptsPeripheral artery diseaseMajor adverse eventsPAD diagnosisAdverse eventsHealth statusMCS scoresLong-term major adverse eventsSelf-reported health statusBaseline clinical dataPeripheral arterial diseaseShort Form-12Time of presentationSubsequent adverse eventsPoor socio-economic statusMental health statusCardiovascular outcomesClinical characteristicsArtery diseaseVascular clinicArterial diseaseForm-12Independent determinantsInitial diagnosisAdverse outcomesPCS scores
2009
Impact of peripheral arterial disease on health status: A comparison with chronic heart failure
Smolderen KG, Pelle AJ, Kupper N, Mols F, Denollet J. Impact of peripheral arterial disease on health status: A comparison with chronic heart failure. Journal Of Vascular Surgery 2009, 50: 1391-1398. PMID: 19958988, DOI: 10.1016/j.jvs.2009.07.109.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAmbulatory Care FacilitiesChronic DiseaseCost of IllnessCross-Sectional StudiesEducational StatusFemaleHeart DiseasesHeart FailureHumansLogistic ModelsMaleMarital StatusMental HealthMiddle AgedNetherlandsOdds RatioPeripheral Vascular DiseasesPropensity ScoreRisk AssessmentRisk FactorsSickness Impact ProfileConceptsPeripheral arterial diseaseChronic heart failurePhysical health statusMental health statusCHF patientsHealth statusPAD patientsCardiac historyDiabetes mellitusHeart failureArterial diseaseMedical recordsMedical conditionsImpact of PADLow ankle-brachial indexPatients' physical health statusYounger ageWorse physical health statusCross-sectional observational studyMental health status scoresComorbid diabetes mellitusAnkle-brachial indexClinical risk factorsHealth status scoresShort Form-12