2023
Incidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty
Weinstein E, Stephens-Shields A, Newcomb C, Silibovsky R, Nelson C, O’Donnell J, Glaser L, Hsieh E, Hanberg J, Tate J, Akgün K, King J, Re V. Incidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty. JAMA Network Open 2023, 6: e2340457. PMID: 37906194, PMCID: PMC10618849, DOI: 10.1001/jamanetworkopen.2023.40457.Peer-Reviewed Original ResearchConceptsPrimary total knee arthroplastyProsthetic joint infectionTotal knee arthroplastyIncidence rate ratiosLate prosthetic joint infectionsPostoperative periodIncidence rateCohort studyOverall cohortJoint infectionKnee arthroplastyVeterans Affairs Surgical Quality Improvement Program dataElective primary total knee arthroplastyEarly prosthetic joint infectionHepatitis C virus infectionQuality Improvement Program dataVeterans Affairs Corporate Data WarehouseAutoimmune inflammatory arthritisPostoperative antibiotic useC virus infectionRisk factor modificationChronic kidney diseasePeripheral artery diseaseLate postoperative periodYears of careAccess to Medically Necessary Reproductive Care for Individuals with Pulmonary Hypertension
Sonntag E, Akgün K, Bag R, Rosensweig E, Bernardo R, Burnetti C, Chybowski A, de Jesus Perez V, Diwan J, Guthrie K, Halscott T, Lahm T, Vaught J, Ventetuolo C, Hemnes A. Access to Medically Necessary Reproductive Care for Individuals with Pulmonary Hypertension. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 234-237. PMID: 37311249, PMCID: PMC10395720, DOI: 10.1164/rccm.202302-0230vp.Peer-Reviewed Original ResearchDesign and methods of a randomized trial testing "Advancing care for COPD in people living with HIV by implementing evidence-based management through proactive E-consults (ACHIEVE)"
Ives J, Bagchi S, Soo S, Barrow C, Akgün K, Erlandson K, Goetz M, Griffith M, Gross R, Hulgan T, Moanna A, Soo Hoo G, Weintrob A, Wongtrakool C, Adams S, Sayre G, Helfrich C, Au D, Crothers K. Design and methods of a randomized trial testing "Advancing care for COPD in people living with HIV by implementing evidence-based management through proactive E-consults (ACHIEVE)". Contemporary Clinical Trials 2023, 132: 107303. PMID: 37481201, PMCID: PMC10528346, DOI: 10.1016/j.cct.2023.107303.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseE-consultsEvidence-based managementElectronic health recordsCOPD managementVeterans Affairs Medical CenterCommon comorbid diseasesObstructive pulmonary diseaseChronic disease comorbiditiesEvidence-based careEvidence-based recommendationsComorbid diseasesPulmonary diseaseHIV populationInappropriate therapyBlood InstituteNational HeartACHIEVE trialMedical CenterClinical providersDisease comorbiditiesHIVPWHTrial testingCareValidation of Electronic Health Record-Based Algorithms to Identify Specialist Palliative Care Within the Department of Veterans Affairs
Feder S, Zhan Y, Abel E, Smith D, Ersek M, Fried T, Redeker N, Akgün K. Validation of Electronic Health Record-Based Algorithms to Identify Specialist Palliative Care Within the Department of Veterans Affairs. Journal Of Pain And Symptom Management 2023, 66: e475-e483. PMID: 37364737, PMCID: PMC10527602, DOI: 10.1016/j.jpainsymman.2023.06.023.Peer-Reviewed Original ResearchConceptsSpecialist palliative careInpatient encountersCurrent Procedural TerminologyPalliative careICD-9/ICDICD-9/10 codesCohort of peopleVeterans Affairs facilitiesStop codeNegative predictive valueElectronic health recordsChart reviewHeart failureAdministrative databasesSpecific clinicPredictive valueICD codesProcedural TerminologyVeterans AffairsOutpatientsHealth recordsAdministrative dataReference standardCareConsultationMedical Societies Must Choose Professional Meeting Locations Responsibly in a Post-Roe World
Lee A, Maley J, Hibbert K, Akgün K, Hauschildt K, Law A, Kaminski N, Hayes M, Gesthalter Y, Bosslet G, Santhosh L, Witkin A, Hills-Dunlap K, Çoruh B, Gershengorn H, Hardin C. Medical Societies Must Choose Professional Meeting Locations Responsibly in a Post-Roe World. Annals Of The American Thoracic Society 2023, 20: 781-784. PMID: 36812378, PMCID: PMC10257035, DOI: 10.1513/annalsats.202211-928ip.Peer-Reviewed Original ResearchAdvance directive screening among veterans with incident heart failure: Comparisons among people aging with and without HIV
Walenczyk K, Cavanagh C, Skanderson M, Feder S, Soliman A, Justice A, Burg M, Akgün K. Advance directive screening among veterans with incident heart failure: Comparisons among people aging with and without HIV. Heart & Lung 2023, 61: 1-7. PMID: 37023581, PMCID: PMC10524135, DOI: 10.1016/j.hrtlng.2023.03.018.Peer-Reviewed Original ResearchConceptsIncident heart failureVeterans Aging Cohort StudyHeart failureAD screeningDisease severityCox proportional hazards regressionIncident HF diagnosisAging Cohort StudyProportional hazards regressionGreater disease severityAdvance directive completionAssociation of ADFuture quality improvementCare contactsCohort studyHF diagnosisHIV statusScreening ratesHazards regressionPoor prognosisDiagnosis codesCardiology subspecialtiesHaenszel testHealthcare encountersPWHVariation in firearm screening and access by LGBT status
Goulet J, Warren A, Workman T, Skanderson M, Farmer M, Gordon K, Abel E, Akgün K, Bean‐Mayberry B, Zeng‐Treitler Q, Haderlein T, Haskell S, Bastian L, Womack J, Post L, Hwang U, Brandt C. Variation in firearm screening and access by LGBT status. Academic Emergency Medicine 2023, 30: 420-423. PMID: 36661348, DOI: 10.1111/acem.14664.Peer-Reviewed Original ResearchDelirium among people aging with and without HIV: Role of alcohol and Neurocognitively active medications
Akgün K, Krishnan S, Tate J, Bryant K, Pisani M, Re V, Rentsch C, Crothers K, Gordon K, Justice A, team F. Delirium among people aging with and without HIV: Role of alcohol and Neurocognitively active medications. Journal Of The American Geriatrics Society 2023, 71: 1861-1872. PMID: 36786300, PMCID: PMC10258127, DOI: 10.1111/jgs.18265.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification Test-ConsumptionActive medicationAlcohol useOdds ratioRelative riskDose-response associationDate of admissionSeverity of illnessIndependent dose-response associationsRace/ethnicityInpatient deliriumIndex dateMedication exposureRole of alcoholHIV statusMultivariable analysisMedication countNeurocognitive dysfunctionUnderappreciated causeDeliriumHigh incidencePWHMedicationsPWOHLogistic regression
2020
Associations of marijuana with markers of chronic lung disease in people living with HIV
Wenger D, Triplette M, Shahrir S, Akgun K, Wongtrakool C, Brown, Kim J, Hoo G, Rodriguez‐Barradas M, Huang L, Feemster L, Zifodya J, Crothers K. Associations of marijuana with markers of chronic lung disease in people living with HIV. HIV Medicine 2020, 22: 92-101. PMID: 33022830, DOI: 10.1111/hiv.12966.Peer-Reviewed Original ResearchConceptsChronic lung diseaseLung diseaseMarijuana smokingRadiographic emphysemaMarijuana exposureHIV-Associated Lung Emphysema (EXHALE) studyLarger total lung capacityHIV-positive patientsTotal lung capacityHigh lung volumesCross-sectional analysisMarijuana useAssociation of marijuanaExpiratory volumeTobacco smokingVital capacityLung capacityLung healthLung volumeSmokingWeekly marijuana useHIVPLWHLogistic regressionEmphysema
2019
Racial Differences in Change in Physical Functioning in Older Male Veterans with HIV
McKellar MS, Kuchibhatla MN, Oursler KAK, Crystal S, Akgün K, Crothers K, Gibert CL, Nieves-Lugo K, Womack J, Tate J, Fillenbaum GG. Racial Differences in Change in Physical Functioning in Older Male Veterans with HIV. AIDS Research And Human Retroviruses 2019, 35: 1034-1043. PMID: 30963773, PMCID: PMC6862951, DOI: 10.1089/aid.2018.0296.Peer-Reviewed Original ResearchConceptsPCS scoresPhysical functioningWhite HIVHIV statusMale veteransHealth behaviorsSF-12 physical component summary scorePhysical component summary scoreLower body mass indexHealth conditionsBetter PCS scoresPoorer PCS scoreHIV-negative menLower PCS scoresComponent summary scoresBody mass indexViral load countOlder male veteransChronic health conditionsLack of exerciseBetter health behaviorsWhite male veteransAssociation of demographicGeneral U.S. populationLow socioeconomic status
2017
The Differential Impact of Emphysema on Respiratory Symptoms and 6-Minute Walk Distance in HIV Infection
Triplette M, Attia E, Akgün K, Campo M, Rodriguez-Barradas M, Pipavath S, Shahrir S, Wongtrakool C, Goetz M, Kim J, Soo Hoo G, Brown ST, Crothers K. The Differential Impact of Emphysema on Respiratory Symptoms and 6-Minute Walk Distance in HIV Infection. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: e23-e29. PMID: 27716727, PMCID: PMC5140705, DOI: 10.1097/qai.0000000000001133.Peer-Reviewed Original ResearchConceptsHIV subjectsChronic coughRespiratory symptomsAirflow obstructionWalk distanceRadiographic emphysemaAssociation of emphysemaHIV uninfected subjectsPulmonary function testingCross-sectional analysisPulmonary symptomsCohort studyHIV infectionHIV statusFunction testingClinical impactEmphysemaEmphysema severitySmoking behaviorMild formSymptomsCoughGreater burdenPhlegmHealth effects
2015
Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia
Barakat LA, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgün KM, Goetz MB, Butt AA, Rodriguez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia. HIV Medicine 2015, 16: 421-430. PMID: 25959543, PMCID: PMC5015437, DOI: 10.1111/hiv.12244.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaVeterans Aging Cohort StudyVACS IndexCAP outcomesAntiretroviral therapyOlder adultsHigher VACS indexDays of dischargeAging Cohort StudyUninfected participantsCohort studyMean LOSHIV infectionLonger LOSClinical outcomesUnadjusted analysesUninfected groupMultivariable modelEligibility criteriaHIVMale veteransMortality rateART useMortalityOutcomes
2014
Implementation of an Electronic Clinical Reminder to Improve Rates of Lung Cancer Screening
Federman DG, Kravetz JD, Lerz KA, Akgǖn K, Ruser C, Cain H, Anderson EF, Taylor C. Implementation of an Electronic Clinical Reminder to Improve Rates of Lung Cancer Screening. The American Journal Of Medicine 2014, 127: 813-816. PMID: 24769298, DOI: 10.1016/j.amjmed.2014.04.010.Peer-Reviewed Original Research