PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory protein
Yao G, Zhu M, Insogna K. PTH-dependent stabilization of RANKL mRNA is associated with increased phosphorylation of the KH-type splicing regulatory protein. Molecular And Cellular Endocrinology 2024, 595: 112412. PMID: 39536935, DOI: 10.1016/j.mce.2024.112412.Peer-Reviewed Original ResearchReceptor activator of nuclear factor kappa-B ligandReceptor activator of nuclear factor kappa-B ligand mRNAAU-rich elementsParathyroid hormone treatmentParathyroid hormoneMRNA stabilityRegulation of mRNA stabilityAU-rich element-binding proteinBinding to AU-rich elementsActivation of transcriptionInhibition of cellular transcriptionRegulate mRNA stabilityCells treated with vehicleSplicing regulatory proteinKH-type splicing regulatory proteinNuclear factor kappa-B ligandAu-richElement-binding proteinTNF family membersCellular transcriptionAssociated with increased phosphorylationPTH exposureRegulatory proteinsBinding proteinCells pre-treated