2017
Use of a Targeted Urine Proteome Assay (TUPA) to identify protein biomarkers of delayed recovery after kidney transplant
Williams KR, Colangelo CM, Hou L, Chung L, Belcher JM, Abbott T, Hall IE, Zhao H, Cantley LG, Parikh CR. Use of a Targeted Urine Proteome Assay (TUPA) to identify protein biomarkers of delayed recovery after kidney transplant. Proteomics Clinical Applications 2017, 11 PMID: 28261998, PMCID: PMC5549272, DOI: 10.1002/prca.201600132.Peer-Reviewed Original ResearchConceptsImmediate graft functionKidney transplantGraft functionLong-term graft outcomeMore effective treatmentsProtein biomarkersIGF patientsGraft outcomeIGF levelsPoor outcomeEffective treatmentKidney implantationClinical relevanceBiomarker panelPotential biomarkersUrine proteomeDGFTransplantBiomarkersPatientsOutcomesTreatmentEarly stagesAssaysPrognosis
2015
Acute Kidney Injury in Liver Disease: Role of Biomarkers
Belcher JM. Acute Kidney Injury in Liver Disease: Role of Biomarkers. Advances In Kidney Disease And Health 2015, 22: 368-375. PMID: 26311598, DOI: 10.1053/j.ackd.2015.06.009.BooksConceptsAcute kidney injuryEtiology of AKINeutrophil gelatinase-associated lipocalinAcute tubular necrosisGelatinase-associated lipocalinHepatorenal syndromeKidney injuryPrerenal azotemiaTubular necrosisFractional excretionInterleukin-18Urinary neutrophil gelatinase-associated lipocalinProgression of AKIKidney tubular injurySetting of cirrhosisOverall poor outcomeRole of biomarkersStandard diagnostic toolAdvanced cirrhosisAKI etiologyCommon complicationTubular injuryCommon etiologyLiver diseasePoor outcome