2018
Acute Kidney Injury and Liver Disease: Incidence, Pathophysiology, Prevention/Treatment, and Outcomes
Belcher J, Parikh C. Acute Kidney Injury and Liver Disease: Incidence, Pathophysiology, Prevention/Treatment, and Outcomes. 2018, 113-131. DOI: 10.1007/978-1-4939-8628-6_7.Peer-Reviewed Original ResearchAcute kidney injuryAcute tubular necrosisHepatorenal syndromeKidney injuryDefinition of AKIRecent consensus criteriaStructural kidney injurySpontaneous bacterial peritonitisPortal hypertension resultsPrevention/treatmentMultiple urinary biomarkersAKI etiologyCreatinine cutoffRenal hypoperfusionGastrointestinal bleedingPrerenal azotemiaRenal functionSecondary insultsTubular necrosisBacterial peritonitisFractional excretionHypertension resultsPathophysiologic cascadeCommon etiologyLiver disease
2012
Association of AKI With mortality and complications in hospitalized patients with cirrhosis
Belcher JM, Garcia‐Tsao G, Sanyal AJ, Bhogal H, Lim JK, Ansari N, Coca SG, Parikh CR, Consortium F. Association of AKI With mortality and complications in hospitalized patients with cirrhosis. Hepatology 2012, 57: 753-762. PMID: 22454364, PMCID: PMC3390443, DOI: 10.1002/hep.25735.Peer-Reviewed Original ResearchConceptsAcute kidney injuryAcute Kidney Injury Network definitionAssociation of AKIDefinition of AKISeverity of AKIProgression of AKIProspective observational cohort studyAKIN stage 1Baseline renal functionObservational cohort studyIncidence of mortalityAKI criteriaAKI severityAKI stageAKIN criteriaAKIN stageHospital mortalityKidney injuryCohort studyDevastating complicationRenal functionHospitalized patientsImproved outcomesEarly diagnosisTimely treatment