2017
Effect of doxazosin on stress reactivity and the ability to resist smoking
Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal Of Psychopharmacology 2017, 31: 830-840. PMID: 28440105, PMCID: PMC5823502, DOI: 10.1177/0269881117699603.Peer-Reviewed Original ResearchConceptsTobacco cravingCortisol levelsSubsequent ad libitum smokingEffects of doxazosinAd libitum smokingNumber of cigarettesNicotine-motivated behaviorsSmoking lapse behaviorΑ1-adrenergic antagonistNicotine-deprived smokersTitration periodPreclinical findingsSmoking cessationNoradrenergic systemTreatment strategiesDoxazosinSmoking behaviorSmokingHuman laboratoryPhysiologic reactivityPilot studyStress reactivityEffects of stressCigarettesStress imagery
2010
Alcohol expectancy increases positive responses to cigarettes in young, escalating smokers
McKee SA, Harrison EL, Shi J. Alcohol expectancy increases positive responses to cigarettes in young, escalating smokers. Psychopharmacology 2010, 210: 355-364. PMID: 20352411, PMCID: PMC2874601, DOI: 10.1007/s00213-010-1831-x.Peer-Reviewed Original ResearchConceptsSmoking behaviorAd lib smoking behaviorExpectation of alcoholHeavy-drinking young adultsDaily cigarette useExperience of smokingSmoking patternsNondaily smokersSubsequent smokingSmokingSingle cigaretteCigarette useAge groupsAlcohol altersSmokersSubjective effectsYoung adultsYoung adulthoodCigarettesPlaceboHigh rateSubjective reactivitySubjective responsesPrimary aimPositive response