2023
Natural Infection of Nyssorhynchus darlingi and Nyssorhynchus benarrochi B with Plasmodium during the Dry Season in the Understudied Low-Transmission Setting of Datem del Marañon Province, Amazonian Peru
Conn J, Bickersmith S, Saavedra M, Morales J, Alava F, Rodriguez G, del Aguila Morante C, Tong C, Alvarez-Antonio C, Huanahui J, Vinetz J, Gamboa D. Natural Infection of Nyssorhynchus darlingi and Nyssorhynchus benarrochi B with Plasmodium during the Dry Season in the Understudied Low-Transmission Setting of Datem del Marañon Province, Amazonian Peru. American Journal Of Tropical Medicine And Hygiene 2023, 109: 288-295. PMID: 37364858, PMCID: PMC10397451, DOI: 10.4269/ajtmh.23-0058.Peer-Reviewed Original ResearchConceptsLow transmission settingsAnnual parasite indexEntomological inoculation rateHuman biting rateHuman landing catchesMinistry of HealthMalaria hotspotsInfective bitesPlasmodium vivaxMalaria transmissionLanding catchesPlasmodium falciparumMalaria researchNatural infectionInoculation rateNyssorhynchus darlingiBiting rateRiverine villagesParasite indexBiteVector control unitsDarlingiLoreto DepartmentInfectionVivax
2021
Heterogeneity in response to serological exposure markers of recent Plasmodium vivax infections in contrasting epidemiological contexts
Rosado J, White MT, Longley RJ, Lacerda M, Monteiro W, Brewster J, Sattabongkot J, Guzman-Guzman M, Llanos-Cuentas A, Vinetz JM, Gamboa D, Mueller I. Heterogeneity in response to serological exposure markers of recent Plasmodium vivax infections in contrasting epidemiological contexts. PLOS Neglected Tropical Diseases 2021, 15: e0009165. PMID: 33591976, PMCID: PMC7909627, DOI: 10.1371/journal.pntd.0009165.Peer-Reviewed Original ResearchConceptsSerological exposure markersBlood-stage infectionLow transmission settingsP. vivax infectionPlasmodium vivax infectionHigh transmission settingsVivax infectionTransmission settingsAntibody titersAntibody responseExposure markersDifferent transmission intensitiesIgG responsesSerological markersPrevious infectionReceiver Operating Characteristic (ROC) analysisEndemic settingsMalaria eliminationPeruvian cohortOperating characteristics analysisP. vivaxMalaria controlRecent exposureInfectionEpidemiological context
2018
Asymptomatic Plasmodium vivax parasitaemia in the low-transmission setting: the role for a population-based transmission-blocking vaccine for malaria elimination
Martin TCS, Vinetz JM. Asymptomatic Plasmodium vivax parasitaemia in the low-transmission setting: the role for a population-based transmission-blocking vaccine for malaria elimination. Malaria Journal 2018, 17: 89. PMID: 29466991, PMCID: PMC5822557, DOI: 10.1186/s12936-018-2243-3.Peer-Reviewed Original ResearchConceptsTransmission-blocking vaccinesPlasmodium vivax parasitaemiaLow transmission settingsControl of transmissionVivax parasitaemiaChloroquine resistanceAsymptomatic carriageMalaria eliminationNew therapiesPlasmodium vivaxImportant causeCarrier stateImmunological interactionsVaccineOnward infectionInfectionParasite transmissionEradication effortsMosquitoesMorbidityParasitaemiaTherapyMortalityDiagnosisVivax