2022
Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil
Ferreira MU, Gamboa D, Torres K, Rodriguez-Ferrucci H, Soto-Calle VE, Pardo K, Fontoura PS, Tomko SS, Gazzinelli RT, Conn JE, Castro MC, Llanos-Cuentas A, Vinetz JM. Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil. American Journal Of Tropical Medicine And Hygiene 2022, 107: 160-167. PMID: 36228907, PMCID: PMC9662230, DOI: 10.4269/ajtmh.21-1272.Peer-Reviewed Original ResearchConceptsMalaria controlAsymptomatic Plasmodium infectionsPredominant malaria parasitePublic health decision makersMalaria control strategiesPublic health implicationsIndoor residual sprayingBetter malaria controlHealth decision makersVector control measuresPlasmodium infectionInfectious reservoirMalaria burdenPlasmodium vivaxBed netsPublic health policymakingElimination programMalaria parasitesResidual sprayingMalaria researchHealth implicationsNyssorhynchus darlingiDiagnostic methodsHealth policymakingResearch NetworkRelative contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon: pooled analysis of individual participant data from population-based cross-sectional surveys
Ferreira MU, Corder RM, Johansen IC, Kattenberg JH, Moreno M, Rosas-Aguirre A, Ladeia-Andrade S, Conn JE, Llanos-Cuentas A, Gamboa D, Rosanas-Urgell A, Vinetz JM. Relative contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon: pooled analysis of individual participant data from population-based cross-sectional surveys. The Lancet Regional Health - Americas 2022, 9: 100169. PMID: 35663000, PMCID: PMC9161731, DOI: 10.1016/j.lana.2021.100169.Peer-Reviewed Original ResearchIndividual participant dataPolymerase chain reactionClinical manifestationsParasite densityMosquito infectionMalaria transmissionPopulation-based cross-sectional surveyParticipant dataMalaria elimination strategiesPopulation-based surveyHigh parasite densityCross-sectional surveyInfected childrenClinical symptomsAsymptomatic infectionUS National InstitutesAsymptomatic carriersParasite carriersInfectious reservoirVivax transmissionInfectionFundação de Amparo à PesquisaChain reactionNational InstituteElimination strategy
2021
Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: Submicroscopic parasitemic blood infects Nyssorhynchus darlingi
Almeida GG, Costa PAC, da Silva Araujo M, Gomes GR, Carvalho AF, Figueiredo MM, Pereira DB, Tada MS, Medeiros JF, da Silva Soares I, Carvalho LH, Kano FS, de Castro M, Vinetz JM, Golenbock DT, do Valle Antonelli L, Gazzinelli RT. Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: Submicroscopic parasitemic blood infects Nyssorhynchus darlingi. PLOS Neglected Tropical Diseases 2021, 15: e0009077. PMID: 34714821, PMCID: PMC8555776, DOI: 10.1371/journal.pntd.0009077.Peer-Reviewed Original ResearchConceptsAsymptomatic individualsP. vivaxP. vivax malaria patientsP. vivax infectionVivax malaria patientsPlasmodium vivax malariaLow endemicity areaMalaria patientsSymptomatic patientsAsymptomatic infectionVivax malariaVivax infectionInfectious reservoirLow parasitemiaUninfected controlsEndemic regionsMalaria transmissionInfectivity ratesMalaria parasitesBiochemical parametersParasitemiaBloodPotential rolePatientsInfection