2024
Reinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis
Grubb K, Lisko J, O'Hair D, Merhi W, Forrest J, Mahoney P, Van Mieghem N, Windecker S, Yakubov S, Williams M, Chetcuti S, Deeb G, Kleiman N, Althouse A, Reardon M. Reinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis. JACC Cardiovascular Interventions 2024, 17: 1007-1016. PMID: 38573257, DOI: 10.1016/j.jcin.2024.01.292.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansIncidenceMalePostoperative ComplicationsProsthesis DesignRandomized Controlled Trials as TopicRetreatmentRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementIncidence of reinterventionAortic valve replacementCumulative incidence of reinterventionValve replacementValve reinterventionCumulative incidenceCoreValve transcatheter aortic valve replacementLow incidence of reinterventionSurgical aortic valve replacement patientsSingle-arm studyFirst-generation CoreValveEvolut R/ProParavalvular regurgitationReinterventionRandomized trialsLow incidenceCoreValvePooled dataTranscatheterIncidenceTreatmentYearsEndocarditis
2023
Impact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis
Ito S, Laham R, Nkomo V, Forrest J, Reardon M, Little S, Mumtaz M, Gada H, Bajwa T, Langholz D, Heiser J, Chawla A, Jenson B, Attizanni G, Markowitz A, Huang J, Oh J. Impact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis. Open Heart 2023, 10: e002297. PMID: 37173100, PMCID: PMC10186477, DOI: 10.1136/openhrt-2023-002297.Peer-Reviewed Original ResearchMeSH KeywordsAortic ValveAortic Valve StenosisHeart Valve Prosthesis ImplantationHumansQuality of LifeTreatment OutcomeConceptsSevere aortic stenosisAortic valve replacementAortic stenosisSymptomatic patientsValve replacementKansas City Cardiomyopathy Questionnaire overall summary scoreEvolut Low Risk trialSurgical aortic valve replacementLow-risk trialsLow-risk patientsOverall summary scoreRate of deathQuality of lifeDisabling strokeEchocardiographic evidenceIsolated AVRHaemodynamic profileClinical outcomesHaemodynamic outcomesRisk trialsClinical trialsCalcium volumeSummary scoresPatientsCore laboratory measurementsTranscatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials
Ahmad Y, Howard J, Arnold A, Madhavan M, Cook C, Alu M, Mack M, Reardon M, Thourani V, Kapadia S, Thyregod H, Sondergaard L, Jørgensen T, Toff W, Van Mieghem N, Makkar R, Forrest J, Leon M. Transcatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials. European Heart Journal 2023, 44: 836-852. PMID: 36660821, DOI: 10.1093/eurheartj/ehac642.Peer-Reviewed Original ResearchMeSH KeywordsAortic ValveAortic Valve StenosisHeart Valve Prosthesis ImplantationHumansRandomized Controlled Trials as TopicRisk FactorsStrokeTreatment OutcomeConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationHigh-risk patientsLow-risk patientsComposite of deathAortic valve replacementValve replacementMAIN OUTCOMENew-onset atrial fibrillationSignificant differencesRandomized clinical trial dataAcute kidney injuryAortic valve implantationMain clinical outcomesRisk of deathClinical trial dataMajor bleedingKidney injurySecondary endpointsVascular complicationsValve implantationClinical outcomesParavalvular leakRandomized trialsAtrial fibrillation
2022
Risk factors and mortality associated with permanent pacemaker after surgical or transcatheter aortic valve replacement: Early versus late implantation
Bin Mahmood SU, Mori M, Amabile A, Prescher L, Forrest J, Kaple R, Geirsson A, Mangi AA. Risk factors and mortality associated with permanent pacemaker after surgical or transcatheter aortic valve replacement: Early versus late implantation. Journal Of Cardiac Surgery 2022, 37: 4295-4300. PMID: 36131523, DOI: 10.1111/jocs.16938.Peer-Reviewed Original ResearchMeSH KeywordsAortic ValveAortic Valve StenosisHeart Valve Prosthesis ImplantationHumansPacemaker, ArtificialRetrospective StudiesRisk FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsMid-term mortalityAortic valve replacementRisk factorsPPM implantationTAVR proceduresValve replacementPermanent pacemakerCox proportional hazards analysisTranscatheter aortic valve replacementTranscatheter aortic valve replacement (TAVR) proceduresAortic valve replacement proceduresRight bundle branch blockYale-New Haven HospitalNon-PPM groupProportional hazards analysisSingle-center evaluationNumber of patientsBundle branch blockValve replacement proceduresFurther subgroup analysisNew Haven HospitalPPM placementTAVR cohortKaplan-MeierPatient populationEmergent Repair of Acute Type A Aortic Dissection From Transcatheter Aortic Valve Replacement
Hameed I, Boix-Garibo R, Ahmed A, Forrest JK, Vallabhajosyula P. Emergent Repair of Acute Type A Aortic Dissection From Transcatheter Aortic Valve Replacement. Canadian Journal Of Cardiology 2022, 38: 404-406. PMID: 35031349, DOI: 10.1016/j.cjca.2022.01.003.Peer-Reviewed Original Research
2018
Trends in volume and risk profiles of patients undergoing isolated surgical and transcatheter aortic valve replacement
Mori M, Bin Mahmood SU, Geirsson A, Yun JJ, Cleman MW, Forrest JK, Mangi AA. Trends in volume and risk profiles of patients undergoing isolated surgical and transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2018, 93: e337-e342. PMID: 30269424, DOI: 10.1002/ccd.27855.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overAortic ValveFemaleHeart Valve Prosthesis ImplantationHospitals, High-VolumeHumansMalePatient Reported Outcome MeasuresPractice Patterns, Physicians'Retrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSurgical aortic valve replacementAortic valve replacementSTS-PROMSAVR volumeSAVR cohortValve replacementCase volumeTranscatheter aortic valve replacementRisk profileTranscatheter aortic valve replacement (TAVR) programHigh-volume academic medical centerRisk categoriesStudy periodContemporary temporal trendsMedian STS PROMProportion of patientsRisk of mortalityLow-risk categoryAcademic medical centerPROM patientsTAVR cohortTAVR volumeTAVR patientsConsecutive patientsIntermediate risk
2017
The SURTAVI study: TAVI for patients with intermediate risk.
Jones DA, Tchétché D, Forrest J, Hellig F, Lansky A, Moat N. The SURTAVI study: TAVI for patients with intermediate risk. EuroIntervention 2017, 13: e617-e620. PMID: 28781252, DOI: 10.4244/eijv13i5a97.Peer-Reviewed Original ResearchAortic ValveAortic Valve StenosisHeart Valve Prosthesis ImplantationHumansRisk FactorsTranscatheter Aortic Valve ReplacementTreatment Outcome1-Year Results in Patients Undergoing Transcatheter Aortic Valve Replacement With Failed Surgical Bioprostheses
Deeb GM, Chetcuti SJ, Reardon MJ, Patel HJ, Grossman PM, Schreiber T, Forrest JK, Bajwa TK, O’Hair D, Petrossian G, Robinson N, Katz S, Hartman A, Dauerman HL, Schmoker J, Khabbaz K, Watson DR, Yakubov SJ, Oh JK, Li S, Kleiman NS, Adams DH, Popma JJ. 1-Year Results in Patients Undergoing Transcatheter Aortic Valve Replacement With Failed Surgical Bioprostheses. JACC Cardiovascular Interventions 2017, 10: 1034-1044. PMID: 28521921, DOI: 10.1016/j.jcin.2017.03.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve InsufficiencyAortic Valve StenosisEchocardiographyFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHemodynamicsHumansKaplan-Meier EstimateMaleMiddle AgedProspective StudiesProsthesis FailureQuality of LifeRecovery of FunctionRecurrenceReoperationRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSelf-expanding transcatheter aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementMajor stroke rateAortic regurgitationValve replacementStroke rateValve hemodynamicsSevere native aortic valve stenosisSuccessful transcatheter aortic valve replacementNative aortic valve stenosisNew permanent pacemaker implantationSevere residual aortic regurgitationValve prosthesis-patient mismatchMean aortic gradientMean valve gradientResidual aortic regurgitationSevere aortic regurgitationProsthesis-patient mismatchCause mortality ratesIndependent core laboratoryModerate aortic regurgitationPermanent pacemaker implantationAortic valve stenosisAortic valve hemodynamics
2016
Transcatheter Aortic Valve Replacement Versus Surgery in Women at High Risk for Surgical Aortic Valve Replacement (from the CoreValve US High Risk Pivotal Trial)
Skelding KA, Yakubov SJ, Kleiman NS, Reardon MJ, Adams DH, Huang J, Forrest JK, Popma JJ. Transcatheter Aortic Valve Replacement Versus Surgery in Women at High Risk for Surgical Aortic Valve Replacement (from the CoreValve US High Risk Pivotal Trial). The American Journal Of Cardiology 2016, 118: 560-566. PMID: 27381665, DOI: 10.1016/j.amjcard.2016.05.051.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisCause of DeathFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansMortalityPostoperative ComplicationsRiskStrokeTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementSevere aortic stenosisValve replacementCause mortalityAortic stenosisHigh riskKansas City Cardiomyopathy Questionnaire summary scoreTAVR-treated patientsSelf-expanding valvesMajor stroke rateSelf-expanding prosthesisQuality of lifeSAVR groupSAVR patientsVersus SurgeryTAVR patientsBaseline characteristicsMajor strokeDiabetes mellitusStroke rateSurvival advantageSummary scoresPatients
2015
Transcatheter aortic valve replacement versus surgical aortic valve replacement in patients with cirrhosis
Thakkar B, Patel A, Mohamad B, Patel NJ, Bhatt P, Bhimani R, Patel A, Arora S, Savani C, Solanki S, Sonani R, Patel S, Patel N, Deshmukh A, Mohamad T, Grines C, Cleman M, Mangi A, Forrest J, Badheka AO. Transcatheter aortic valve replacement versus surgical aortic valve replacement in patients with cirrhosis. Catheterization And Cardiovascular Interventions 2015, 87: 955-962. PMID: 26699085, DOI: 10.1002/ccd.26345.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBlood TransfusionCardiac CatheterizationChi-Square DistributionCross-Sectional StudiesDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital CostsHumansLength of StayLiver CirrhosisLogistic ModelsMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsPropensity ScoreRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementValve replacementNational Inpatient SampleCirrhosis patientsTAVR groupComplication rateICD-9-CM diagnosis codesICD-9-CM procedureHospital mortality rateSevere aortic stenosisHigh-risk patientsOpen heart surgeryYears of agePostprocedural lengthSAVR groupHospital outcomesOperative morbidityPortal hypertensionAortic stenosisCardiac surgeryCardiopulmonary bypassEsophageal varicesLiver cirrhosisTranscatheter pulmonary valve implantation: A cross-sectional US experience
Patel A, Patel A, Bhatt P, Savani C, Thakkar B, Sonani R, Patel NJ, Arora S, Panaich S, Singh V, Patel S, Pant S, Ansari MM, Deshmukh A, Patel N, Dave A, Grines C, Cleman M, Forrest JK, Badheka AO. Transcatheter pulmonary valve implantation: A cross-sectional US experience. International Journal Of Cardiology 2015, 199: 186-188. PMID: 26197405, DOI: 10.1016/j.ijcard.2015.07.021.Peer-Reviewed Original ResearchSafety and performance of a novel embolic deflection device in patients undergoing transcatheter aortic valve replacement: results from the DEFLECT I study.
Baumbach A, Mullen M, Brickman AM, Aggarwal SK, Pietras CG, Forrest JK, Hildick-Smith D, Meller SM, Gambone L, den Heijer P, Margolis P, Voros S, Lansky AJ. Safety and performance of a novel embolic deflection device in patients undergoing transcatheter aortic valve replacement: results from the DEFLECT I study. EuroIntervention 2015, 11: 75-84. PMID: 25868876, DOI: 10.4244/eijy15m04_01.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlloysAortic ValveAortic Valve StenosisBrain IschemiaBrazilCardiac CatheterizationCognitionCognition DisordersDiffusion Magnetic Resonance ImagingEmbolic Protection DevicesEuropeFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansIntracranial EmbolismMalePredictive Value of TestsProspective StudiesProsthesis DesignRisk FactorsSeverity of Illness IndexStrokeTime FactorsTreatment OutcomeUltrasonography, Doppler, TranscranialConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementNew cerebral ischemic lesionsCerebral diffusion-weighted magnetic resonance imagingCerebral ischemic lesionsDays post procedurePrimary safety endpointDiffusion-weighted magnetic resonance imagingMajor cerebral arteriesTotal lesion volumeMagnetic resonance imagingSafety endpointIschemic lesionsTAVR proceduresCerebral arteryCerebral circulationConsecutive subjectsPost procedureAortic archHistorical controlsLesion volumeResonance imagingDW-MRIPatientsA balloon-expandable sheath facilitates transfemoral TAVR in patients with peripheral vascular disease and tortuosity
Goldsweig AM, Faheem O, Cleman MW, Forrest JK. A balloon-expandable sheath facilitates transfemoral TAVR in patients with peripheral vascular disease and tortuosity. Therapeutic Advances In Cardiovascular Disease 2015, 9: 95-102. PMID: 25784499, DOI: 10.1177/1753944715575970.Peer-Reviewed Original ResearchMeSH KeywordsAortic ValveArteriesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansJoint InstabilityPeripheral Arterial DiseaseSkin Diseases, GeneticSurvival RateTreatment OutcomeVascular MalformationsConceptsTransfemoral transcatheter aortic valve replacementTranscatheter aortic valve replacementPeripheral arterial diseaseSurgical aortic valve replacementBalloon-expandable sheathAortic valve replacementVascular tortuosityValve replacementTransfemoral approachSuccessful transcatheter aortic valve replacementVascular access complicationsPeripheral vascular diseaseTerms of mortalityPostprocedural angiographyTAVR resultsAccess complicationsSurgical cutdownSurgical riskArterial diseaseSevere stenosisVascular accessTransapical accessVascular diseaseMortality riskPatientsTranscatheter aortic valve replacement
Forrest JK, Mangi A, Vaitkeviciute I. Transcatheter aortic valve replacement. Current Opinion In Anaesthesiology 2015, 28: 107-112. PMID: 25486491, DOI: 10.1097/aco.0000000000000142.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesiaCardiac CatheterizationHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansPerioperative CareTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementSurgical aortic valve replacementAortic valve replacementValve replacementTreatment optionsHeart teamAortic stenosisFrequent valvular heart diseaseHeart team approachOnly definitive treatmentMultidisciplinary heart teamValvular heart diseaseBest treatment optionType of treatmentDefinitive treatmentTAVR proceduresPatient selectionLocal anesthesiaPatient populationHeart diseaseAccess sitePatientsCath labTeam approachStenosis
2012
Transcatheter aortic valve replacement: design, clinical application, and future challenges.
Forrest JK. Transcatheter aortic valve replacement: design, clinical application, and future challenges. The Yale Journal Of Biology And Medicine 2012, 85: 239-47. PMID: 22737052, PMCID: PMC3375667.Peer-Reviewed Original ResearchMeSH KeywordsAortic ValveAortic Valve StenosisCardiac CatheterizationForecastingHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansOutcome Assessment, Health CareProsthesis DesignRandomized Controlled Trials as TopicConceptsTranscatheter aortic valve replacementSurgical candidatesAortic stenosisTranscatheter valveSevere symptomatic aortic stenosisSymptomatic aortic stenosisAortic valve replacementEdwards SAPIEN valveQuality of lifeSAPIEN valveMedtronic CoreValveValve replacementClinical resultsPatientsClinical applicationStenosisMechanism of deliveryValveCoreValve