2023
Association Between Claims‐Defined Frailty and Outcomes Following 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: Findings From the EXTEND‐DAPT Study
Faridi K, Strom J, Kundi H, Butala N, Curtis J, Gao Q, Song Y, Zheng L, Tamez H, Shen C, Secemsky E, Yeh R. Association Between Claims‐Defined Frailty and Outcomes Following 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: Findings From the EXTEND‐DAPT Study. Journal Of The American Heart Association 2023, 12: e029588. PMID: 37449567, PMCID: PMC10382113, DOI: 10.1161/jaha.123.029588.Peer-Reviewed Original ResearchConceptsExtended duration dual antiplatelet therapyDuration dual antiplatelet therapyNet adverse clinical eventsDual antiplatelet therapyAdverse clinical eventsPercutaneous coronary interventionCoronary interventionClinical eventsNonfrail patientsAntiplatelet therapyFrail patientsClaims dataMonths of DAPTClaims-based indexYears of ageMajor bleedingCause mortalityMultivariable adjustmentOlder patientsDAPT studyResults PatientsBackground FrailtyMyocardial infarctionClinical trialsMedicare claimsRacial Differences in Presentation and Outcomes After Peripheral Arterial Interventions: Insights From the NCDR-PVI Registry
Julien H, Wang Y, Curtis J, Johnston-Cox H, Eberly L, Wang G, Nathan A, Fanaroff A, Khatana S, Groeneveld P, Secemsky E, Eneanya N, Vora A, Kobayashi T, Barbery C, Chery G, Kohi M, Kirksey L, Armstrong E, Jaff M, Giri J. Racial Differences in Presentation and Outcomes After Peripheral Arterial Interventions: Insights From the NCDR-PVI Registry. Circulation Cardiovascular Interventions 2023, 16: e011485. PMID: 37339237, DOI: 10.1161/circinterventions.121.011485.Peer-Reviewed Original ResearchConceptsDistressed Communities Index scorePeripheral arterial interventionsBlack patientsDrug-eluting technologiesWhite patientsArterial interventionsIndex scoreAcute kidney injuryRate of amputationSocioeconomic statusMultivariable logistic regressionPatient's zip codeZip codesMedicaid Services dataLow socioeconomic statusHigh ratePVI procedureKidney injuryMajor amputationIntervention RegistryHigh prevalenceAmerican CollegePatientsRevascularizationLogistic regressionVariation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes
Chui P, Lan Z, Freeman J, Enriquez A, Khera R, Akar J, Masoudi F, Ong E, Curtis J. Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes. Heart Rhythm 2023, 20: 1000-1008. PMID: 36963741, DOI: 10.1016/j.hrthm.2023.03.022.Peer-Reviewed Original ResearchConceptsEligible patientsICD RegistryCardiac resynchronizationNational Cardiovascular Data Registry ICD RegistryCRT-D implantationCRT-D useHospital-level outcomesStrong guideline recommendationsHospital-level variationPatient-level outcomesIntraclass correlation coefficientQuality improvement effortsHospital mortalityGuideline indicationsReadmission ratesSelect patientsClinical outcomesGuideline recommendationsHospital variationHospital ratesUse of CRTHospital levelHospital usePatientsCase mix
2022
Clinical Outcomes at 1 Year Following Transcatheter Left Atrial Appendage Occlusion in the United States
Price MJ, Slotwiner D, Du C, Freeman JV, Turi Z, Rammohan C, Kusumoto FM, Kavinsky C, Akar J, Varosy PD, Koutras C, Curtis JP, Masoudi FA. Clinical Outcomes at 1 Year Following Transcatheter Left Atrial Appendage Occlusion in the United States. JACC Cardiovascular Interventions 2022, 15: 741-750. PMID: 35393108, PMCID: PMC9116488, DOI: 10.1016/j.jcin.2022.02.009.Peer-Reviewed Original ResearchConceptsAtrial appendage occlusionIschemic strokeMajor bleedingClinical outcomesSystemic embolismAppendage occlusionMean HAS-BLED scoreHAS-BLED scoreKey secondary endpointKaplan-Meier methodCumulative event rateRate of mortalityMean CHAPrior strokeRelevant bleedingVASc scoreWATCHMAN procedurePrimary endpointSecondary endpointsThromboembolic eventsIntracranial bleedingBlood transfusionHemoglobin levelsHemorrhagic strokeKaplan-MeierLongitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients
Friedman DJ, Qin L, Parzynski C, Heist EK, Russo AM, Ranasinghe I, Zeitler EP, Minges KE, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM. Longitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients. Journal Of The American College Of Cardiology 2022, 79: 1050-1059. PMID: 35300816, DOI: 10.1016/j.jacc.2021.12.033.Peer-Reviewed Original ResearchConceptsOlder patientsCause readmissionS-ICDNational Cardiovascular Data Registry ICD RegistryDevice removalTransvenous implantable cardioverter defibrillatorTV-ICD patientsRisk of deathS-ICD patientsService Medicare beneficiariesAnderson-Gill modelsImplantable cardioverter defibrillatorRepresentative national cohortCompeting-risks modelTV-ICDCardiovascular readmissionCause mortalityICD implantationYounger patientsICD RegistryNonfatal outcomesTransvenous ICDAtrial fibrillationNational cohortCardioverter defibrillator
2021
Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation
Bourdillon PM, Parzynski CS, Minges KE, Curtis JP, Desai NR. Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation. Journal Of Cardiac Failure 2021, 28: 154-160. PMID: 34628015, DOI: 10.1016/j.cardfail.2021.09.010.Peer-Reviewed Original ResearchConceptsHospital adverse eventsHospital outcomesAdverse eventsHeart failureMyocardial infarctionRecent acute myocardial infarctionPlacement of ICDsPrimary prevention ICDsAdverse event ratesRecent myocardial infarctionAcute myocardial infarctionHigh mortality rateICD implantationRecent diagnosisMortality ratePatientsICDInfarctionHospitalOutcomesRapid reductionUse of devicesFailureSpecific reasonsCriteriaComparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease
Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Comparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease. Circulation Cardiovascular Interventions 2021, 14: e010323. PMID: 34372676, PMCID: PMC8485756, DOI: 10.1161/circinterventions.120.010323.Peer-Reviewed Original ResearchPrognosis of Claims‐ Versus Trial‐Based Ischemic and Bleeding Events Beyond 1 Year After Coronary Stenting
Butala NM, Faridi KF, Secemsky EA, Song Y, Curtis J, Gibson CM, Kazi D, Shen C, Yeh RW. Prognosis of Claims‐ Versus Trial‐Based Ischemic and Bleeding Events Beyond 1 Year After Coronary Stenting. Journal Of The American Heart Association 2021, 10: e018744. PMID: 33682431, PMCID: PMC8174225, DOI: 10.1161/jaha.120.018744.Peer-Reviewed Original ResearchConceptsUnadjusted mortality ratesIschemic eventsDAPT studyMortality rateEnd pointCox proportional hazards modelPercutaneous coronary interventionProportional hazards modelCardiovascular clinical trialsTrial adjudicationBleeding eventsCathPCI RegistryCoronary interventionCoronary stentingSimilar prognosisPrognostic significanceClinical eventsClinical trialsMedicare claimsAdministrative claimsMortality riskHazards modelPatientsPrognosisDeathComparability of Event Adjudication Versus Administrative Billing Claims for Outcome Ascertainment in the DAPT Study
Faridi KF, Tamez H, Butala NM, Song Y, Shen C, Secemsky EA, Mauri L, Curtis JP, Strom JB, Yeh RW. Comparability of Event Adjudication Versus Administrative Billing Claims for Outcome Ascertainment in the DAPT Study. Circulation Cardiovascular Quality And Outcomes 2021, 14: e006589. PMID: 33435731, PMCID: PMC7855905, DOI: 10.1161/circoutcomes.120.006589.Peer-Reviewed Original ResearchConceptsNegative predictive valuePositive predictive valueMyocardial infarctionPredictive valueDAPT studyClinical trialsAdjudicated eventsClaims dataNational Cardiovascular Data Registry CathPCI RegistryClinical events committeeTrial of patientsPercutaneous coronary interventionTrial end pointsKappa statisticsAdjudicated deathCathPCI RegistryCerebrovascular eventsCoronary interventionCumulative incidenceEvents committeeOutcome ascertainmentBilling claimsInpatient hospitalizationBleeding rateCardiovascular diseaseUse and Outcomes of Dual Chamber or Cardiac Resynchronization Therapy Defibrillators Among Older Patients Requiring Ventricular Pacing in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Borne RT, Masoudi FA, Curtis JP, Zipse MM, Sandhu A, Hsu JC, Peterson PN. Use and Outcomes of Dual Chamber or Cardiac Resynchronization Therapy Defibrillators Among Older Patients Requiring Ventricular Pacing in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Network Open 2021, 4: e2035470. PMID: 33496796, PMCID: PMC7838925, DOI: 10.1001/jamanetworkopen.2020.35470.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyHeart failure hospitalizationClass I indicationsUse of CRTFailure hospitalizationMedian odds ratioCohort studyOlder patientsVentricular pacingImplant ratesNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryNational Cardiovascular Data Registry ICD RegistryReduced left ventricular ejection fractionMultivariable Cox proportional hazards modelsFrequent right ventricular pacingImplantable Cardioverter-Defibrillator RegistryPrior heart failure hospitalizationLeft ventricular ejection fractionImplantable cardioverter defibrillator implantationThird-degree atrioventricular blockCardiac resynchronization therapy defibrillatorCox proportional hazards modelBradycardia pacing indicationFirst-time implantationFrequent RV pacing
2020
Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals
Murugiah K, Annapureddy AR, Khera R, Lansky A, Curtis JP. Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals. Catheterization And Cardiovascular Interventions 2020, 97: e624-e626. PMID: 32833350, DOI: 10.1002/ccd.29217.Peer-Reviewed Original ResearchConceptsCardiac catheterization laboratoryCardiovascular HospitalFellowship trainingPercutaneous coronary interventionCardiac catheterization laboratory directorsStructural interventionsCoronary interventionMedian agePeripheral interventionsMedical school graduationCardiovascular programCatheterization laboratoryMedicare dataMedicare Provider UtilizationHospitalClinical focusMedian yearsProvider UtilizationUse of Administrative Claims Data to Estimate Treatment Effects for 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention
Faridi KF, Tamez H, Strom JB, Song Y, Butala NM, Shen C, Secemsky EA, Mauri L, Curtis JP, Gibson CM, Yeh RW. Use of Administrative Claims Data to Estimate Treatment Effects for 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention. Circulation 2020, 142: 306-308. PMID: 32687440, PMCID: PMC7374757, DOI: 10.1161/circulationaha.120.047729.Peer-Reviewed Original ResearchAttribution of Adverse Events Following Coronary Stent Placement Identified Using Administrative Claims Data
Dhruva SS, Parzynski CS, Gamble GM, Curtis JP, Desai NR, Yeh RW, Masoudi FA, Kuntz R, Shaw RE, Marinac‐Dabic D, Sedrakyan A, Normand S, Krumholz HM, Ross JS. Attribution of Adverse Events Following Coronary Stent Placement Identified Using Administrative Claims Data. Journal Of The American Heart Association 2020, 9: e013606. PMID: 32063087, PMCID: PMC7070203, DOI: 10.1161/jaha.119.013606.Peer-Reviewed Original ResearchMeSH KeywordsAdministrative Claims, HealthcareAgedAged, 80 and overCoronary RestenosisCoronary ThrombosisDatabases, FactualDrug-Eluting StentsFemaleHumansMaleMedicareMyocardial InfarctionPercutaneous Coronary InterventionProduct Surveillance, PostmarketingRegistriesRetreatmentRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsIndex percutaneous coronary interventionPercutaneous coronary interventionSame coronary arteryDrug-eluting stentsNCDR CathPCI RegistrySubsequent percutaneous coronary interventionAcute myocardial infarctionCoronary arteryClaims dataCathPCI RegistryAdverse eventsIndex procedureMyocardial infarctionRepeat percutaneous coronary interventionReal-world registry dataTarget vessel revascularizationCoronary stent placementAdministrative claims dataLong-term safetyLongitudinal claims dataPotential safety eventsVessel revascularizationCoronary interventionDES placementStent thrombosis
2019
Comparison of Clinical Trials and Administrative Claims to Identify Stroke Among Patients Undergoing Aortic Valve Replacement
Strom JB, Zhao Y, Faridi KF, Tamez H, Butala NM, Valsdottir LR, Curtis J, Brennan JM, Shen C, Boulware M, Popma JJ, Yeh RW. Comparison of Clinical Trials and Administrative Claims to Identify Stroke Among Patients Undergoing Aortic Valve Replacement. Circulation Cardiovascular Interventions 2019, 12: e008231. PMID: 31694411, PMCID: PMC7212938, DOI: 10.1161/circinterventions.119.008231.Peer-Reviewed Original ResearchMeSH KeywordsAdministrative Claims, HealthcareAgedAged, 80 and overAortic ValveAortic Valve StenosisBrain IschemiaClinical Trials as TopicDatabases, FactualFemaleHeart Valve Prosthesis ImplantationHumansIschemic Attack, TransientMaleMedicareRisk AssessmentRisk FactorsStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsNegative predictive valueAortic valve replacementCerebrovascular eventsInternational ClassificationPositive predictive valuePredictive valueValve replacementNinth RevisionClinical trialsTenth RevisionBilling codesKaplan-Meier estimatesMedicare inpatient claimsSURTAVI trialClinical event adjudicationDevastating complicationIschemic strokeNeurological eventsCerebrovascular diseaseBilling claimsInpatient claimsEvent adjudicationAdministrative claimsHigh riskTrial participantsMyocardial infarction with non-obstructive coronary arteries as compared with myocardial infarction and obstructive coronary disease: outcomes in a Medicare population
Dreyer RP, Tavella R, Curtis JP, Wang Y, Pauspathy S, Messenger J, Rumsfeld JS, Maddox TM, Krumholz HM, Spertus JA, Beltrame JF. Myocardial infarction with non-obstructive coronary arteries as compared with myocardial infarction and obstructive coronary disease: outcomes in a Medicare population. European Heart Journal 2019, 41: 870-878. PMID: 31222249, PMCID: PMC7778433, DOI: 10.1093/eurheartj/ehz403.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsAcute myocardial infarctionHeart failureMyocardial infarctionCoronary angiographyComponents of MACENational Cardiovascular Data Registry CathPCI RegistryNon-obstructive coronary arteriesObstructive coronary artery diseaseAdverse cardiac eventsMajor adverse eventsObservational cohort studyObstructive coronary diseasePrognosis of patientsCoronary artery diseaseMACE componentsMINOCA patientsAdjusted riskCause mortalityPrimary endpointSecondary endpointsAdverse eventsCardiac eventsCathPCI RegistryCohort studyAssociation of Physician Specialty With Long-Term Implantable Cardioverter-Defibrillator Complication and Reoperations Rates
Chui PW, Wang Y, Ranasinghe I, Mitiku TY, Seto AH, Rosman L, Lampert R, Minges KE, Enriquez AD, Curtis JP. Association of Physician Specialty With Long-Term Implantable Cardioverter-Defibrillator Complication and Reoperations Rates. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005374. PMID: 31185734, PMCID: PMC7412734, DOI: 10.1161/circoutcomes.118.005374.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overClinical CompetenceDefibrillators, ImplantableElectric CountershockFee-for-Service PlansFemaleHumansIncidenceMaleMedicarePostoperative ComplicationsPractice Patterns, Physicians'RegistriesReoperationRisk AssessmentRisk FactorsSpecializationTime FactorsTreatment OutcomeUnited StatesConceptsLong-term device-related complicationsDevice-related complicationsICD implantationLong-term outcomesPhysician specialtyGeneral cardiologistsThoracic surgeonsHigh riskNational Cardiovascular Data Registry ICD RegistryLong-term adverse outcomesImplantable cardioverter defibrillator implantationPhysician specialty trainingCardioverter-defibrillator implantationCumulative incidence rateCase-mix adjusted ratesReoperation rateBackground PatientsConclusions PatientsICD RegistryPrimary outcomeAdverse outcomesIncidence rateInterventional cardiologistsAdjusted ratesReoperationCardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block
Kawata H, Bao H, Curtis JP, Minges KE, Mitiku T, Birgersdotter-Green U, Feld GK, Hsu JC. Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block. Journal Of The American College Of Cardiology 2019, 73: 3082-3099. PMID: 31221257, DOI: 10.1016/j.jacc.2019.04.025.Peer-Reviewed Original ResearchConceptsNonspecific intraventricular conduction delayRight bundle branch blockCardiac resynchronization therapyCRT-D implantationCRT-eligible patientsBundle branch blockQRS durationHazard ratioBranch blockBetter outcomesCardiac resynchronization defibrillator therapyMultivariable adjusted hazard ratiosAdjusted hazard ratioIntraventricular conduction delayCareful patient selectionEligible patientsDefibrillator therapyMultivariable adjustmentResynchronization therapyClinical outcomesPatient selectionConduction abnormalitiesRegistry dataConduction delayPatientsOutcomes and costs of remote patient monitoring among patients with implanted cardiac defibrillators: An economic model based on the PREDICT RM database
Hummel JP, Leipold RJ, Amorosi SL, Bao H, Deger KA, Jones PW, Kansal AR, Ott LS, Stern S, Stein K, Curtis JP, Akar JG. Outcomes and costs of remote patient monitoring among patients with implanted cardiac defibrillators: An economic model based on the PREDICT RM database. Journal Of Cardiovascular Electrophysiology 2019, 30: 1066-1077. PMID: 30938894, PMCID: PMC6850124, DOI: 10.1111/jce.13934.Peer-Reviewed Original ResearchAgedAged, 80 and overArrhythmias, CardiacCost-Benefit AnalysisDatabases, FactualDeath, Sudden, CardiacDefibrillators, ImplantableElectric CountershockFemaleHealth Care CostsHumansMaleMedicareModels, EconomicPatient ReadmissionPredictive Value of TestsQuality-Adjusted Life YearsRegistriesRemote Sensing TechnologyTelemetryTime FactorsTreatment OutcomeUnited States
2018
Outcomes following implantable cardioverter-defibrillator generator replacement in patients with recovered left ventricular systolic function: The National Cardiovascular Data Registry
Thomas IC, Wang Y, See VY, Minges KE, Curtis JP, Hsu JC. Outcomes following implantable cardioverter-defibrillator generator replacement in patients with recovered left ventricular systolic function: The National Cardiovascular Data Registry. Heart Rhythm 2018, 16: 733-740. PMID: 30414460, DOI: 10.1016/j.hrthm.2018.11.005.Peer-Reviewed Original ResearchConceptsLV ejection fractionNational Cardiovascular Data Registry ICD RegistryReduced LV ejection fractionICD generator replacementLeft ventricular systolic functionVentricular systolic functionHF readmissionSystolic functionGenerator replacementAdverse outcomesImplantable Cardioverter-Defibrillator Generator ReplacementNational Cardiovascular Data RegistryLV systolic functionEjection fractionICD RegistryPeriprocedural eventsPrognostic associationAmerican CollegeHigh riskData registryLower riskMedicare beneficiariesPatientsReadmissionClinical encountersClinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction
Kini V, Peterson PN, Spertus JA, Kennedy KF, Arnold SV, Wasfy JH, Curtis JP, Bradley SM, Amin AP, Ho PM, Masoudi FA. Clinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004788. PMID: 30354578, PMCID: PMC6214661, DOI: 10.1161/circoutcomes.118.004788.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionPredictors of readmissionSimple risk scoreDays of hospitalizationGroup of patientsProportional hazards regressionCause readmissionCoronary revascularizationClinical characteristicsCohort studyHospital dischargeDiabetes mellitusHeart failureHazards regressionReadmission riskUnique patientsTransitional careACTION RegistryPrimary diagnosisValue-based reimbursementIndividual patientsReadmissionRisk scoreLower risk