2024
Association of Chronic Kidney Disease and Kidney Failure with Replacement Therapy with Procedural and Long-Term Outcomes after First Generation Watchman Device: Insights from the NCDR LAAO Registry
Munir M, Tan Z, Pun P, Wang Y, Tandar A, Darden D, Hsu J, Friedman D, Curtis J, Freeman J. Association of Chronic Kidney Disease and Kidney Failure with Replacement Therapy with Procedural and Long-Term Outcomes after First Generation Watchman Device: Insights from the NCDR LAAO Registry. Heart Rhythm 2024 PMID: 39515495, DOI: 10.1016/j.hrthm.2024.10.071.Peer-Reviewed Original ResearchChronic kidney diseaseLong-term outcomesLeft atrial appendage occlusionAssociation of chronic kidney diseaseNational Cardiovascular Data Registry LAAO RegistryReplacement therapyAdverse eventsAtrial fibrillationKidney diseaseKidney failureAssociated with higher ratesIn-hospital deathRisk of strokeRate of strokeBilling claimsAF patientsProcedural complicationsAppendage occlusionWatchman deviceMultivariate analysisKFRTHigh riskPatientsRegistryComplicationsProcedural Volume and Outcomes with Atrial Fibrillation Ablation: A Report from the NCDR AFib Ablation Registry
Kattel S, Tan Z, Lin Z, Mszar R, Sanders P, Zeitler E, Zei P, Bunch T, Mansour M, Akar J, Curtis J, Friedman D, Freeman J. Procedural Volume and Outcomes with Atrial Fibrillation Ablation: A Report from the NCDR AFib Ablation Registry. Heart Rhythm 2024 PMID: 38960302, DOI: 10.1016/j.hrthm.2024.06.056.Peer-Reviewed Original ResearchProcedure volumeProcedural successVolume outcome relationshipAblation RegistryPhysician procedure volumeAtrial fibrillationPhysician volumeFirst-time AF ablationU.S. hospitalsNational cohortLikelihood of procedural successHospital volumeAcute procedural successAtrial fibrillation ablationPhysiciansHospitalAF ablationCompare outcomesNCDRRegistryAdverse eventsOutcome relationshipAnnual volumeMAE rateOutcomes
2023
Watchman device migration and embolization: A report from the NCDR LAAO Registry
Friedman D, Freeman J, Zimmerman S, Tan Z, Pereira L, Faridi K, Curtis J. Watchman device migration and embolization: A report from the NCDR LAAO Registry. Journal Of Cardiovascular Electrophysiology 2023, 34: 1192-1195. PMID: 37078339, PMCID: PMC10290479, DOI: 10.1111/jce.15909.Peer-Reviewed Original ResearchConceptsWATCHMAN procedureSurgical retrievalDevice migrationMortality rateAtrial appendage closure deviceHospital mortality rateAnnual procedure volumeCardiac surgeryHospital eventsPostdischarge eventsOstial sizeDevice embolizationTaller patientsRetrospective analysisClosure deviceLAA ostiumPatientsProcedure volumeHigh mortalitySurgerySubstantial proportionEmbolizationRegistryGreater body massBody mass
2022
Development and validation of an automated algorithm for end point adjudication for a large U.S. national registry
Friedman DJ, Pierre D, Wang Y, Gambone L, Koutras C, Segawa C, Farb A, Vemulapalli S, Varosy PD, Masoudi FA, Lansky A, Curtis JP, Freeman JV. Development and validation of an automated algorithm for end point adjudication for a large U.S. national registry. American Heart Journal 2022, 254: 102-111. PMID: 36007567, DOI: 10.1016/j.ahj.2022.08.006.Peer-Reviewed Original ResearchConceptsEnd point adjudicationCEC adjudicationEnd pointLarge registriesClinical trialsNational Cardiovascular Data RegistryMajor vascular complicationsU.S. National RegistryPost-discharge eventsAgreement rateMajor bleedingNeurologic eventsVascular complicationsNational registryEvent adjudicationData registryRegistryCommittee's evaluationsPercent agreementGold standardAgreement thresholdHospitalTrialsFurther confirmationBleedingPO-647-01 LEFT VENTRICULAR LEAD IMPLANTATION FAILURE: A REPORT FROM THE NATIONAL CARDIOVASCULAR DATA REGISTRY
Friedman D, Freeman J, Singh J, Curtis J, Piccini J, Al-Khatib S, Jackson K. PO-647-01 LEFT VENTRICULAR LEAD IMPLANTATION FAILURE: A REPORT FROM THE NATIONAL CARDIOVASCULAR DATA REGISTRY. Heart Rhythm 2022, 19: s231. DOI: 10.1016/j.hrthm.2022.03.199.Peer-Reviewed Original ResearchClinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion Insights From the NCDR LAAO Registry
Alkhouli M, Du C, Killu A, Simard T, Noseworthy PA, Friedman PA, Curtis JP, Freeman JV, Holmes DR. Clinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion Insights From the NCDR LAAO Registry. JACC Clinical Electrophysiology 2022, 8: 766-778. PMID: 35387751, PMCID: PMC9233062, DOI: 10.1016/j.jacep.2022.03.001.Peer-Reviewed Original ResearchConceptsPeri-device leakAdverse eventsResidual leakMajor adverse eventsProportion of patientsAdverse clinical eventsAtrial appendage occlusionAnticoagulant utilizationMajor bleedingSystemic embolizationAppendage occlusionClinical eventsClinical impactHigher oddsHigh incidencePatientsThromboembolicSignificant differencesRegistryLarge leaksLAAOLeakHigher proportionDaysAnticoagulation
2021
B-PO03-155 OUTCOMES OF LEFT ATRIAL APPENDAGE OCCLUSION WITH WATCHMAN IN CONTEMPORARY CLINICAL PRACTICE COMPARED WITH CLINICAL TRIALS: A POOLED ANALYSIS OF PROTECT-AF, PREVAIL, AND THE NCDR LAAO REGISTRY
Friedman D, Du C, Agarwal Y, Varosy P, Masoudi F, Curtis J, Freeman J. B-PO03-155 OUTCOMES OF LEFT ATRIAL APPENDAGE OCCLUSION WITH WATCHMAN IN CONTEMPORARY CLINICAL PRACTICE COMPARED WITH CLINICAL TRIALS: A POOLED ANALYSIS OF PROTECT-AF, PREVAIL, AND THE NCDR LAAO REGISTRY. Heart Rhythm 2021, 18: s252. DOI: 10.1016/j.hrthm.2021.06.628.Peer-Reviewed Original ResearchComparing Baseline Data From Registries With Trials Evidence From the CathPCI Registry and DAPT Study
Butala NM, Faridi KF, Secemsky EA, Song Y, Curtis J, Gibson CM, Brindis R, Shen C, Yeh RW. Comparing Baseline Data From Registries With Trials Evidence From the CathPCI Registry and DAPT Study. JACC Cardiovascular Interventions 2021, 14: 1386-1388. PMID: 34167685, PMCID: PMC8800637, DOI: 10.1016/j.jcin.2021.03.065.Peer-Reviewed Original ResearchIN-HOSPITAL MORTALITY RISK PREDICTION FOR PERCUTANEOUS CORONARY INTERVENTIONS: AN UPDATED MODEL FROM THE NCDR CATHPCI REGISTRY
Dominguez Y, Minges K, Wang Y, McNamara R, Spertus J, Dehmer G, Messenger J, Mercado N, Lavin K, Pierre D, Anderson C, Blankinship K, Clary J, Osborne A, Curtis J, Cavender M. IN-HOSPITAL MORTALITY RISK PREDICTION FOR PERCUTANEOUS CORONARY INTERVENTIONS: AN UPDATED MODEL FROM THE NCDR CATHPCI REGISTRY. Journal Of The American College Of Cardiology 2021, 77: 1217. DOI: 10.1016/s0735-1097(21)02576-6.Peer-Reviewed Original ResearchImpact of insurance status on ICD implantation practice patterns: Insights from the NCDR ICD registry
Ahmed I, Merchant FM, Curtis JP, Parzynski CS, Lampert R. Impact of insurance status on ICD implantation practice patterns: Insights from the NCDR ICD registry. American Heart Journal 2021, 235: 44-53. PMID: 33503408, DOI: 10.1016/j.ahj.2021.01.016.Peer-Reviewed Original ResearchConceptsOptimal medical therapyInsurance statusNCDR ICD RegistryMedical therapyComplication rateICD RegistryUninsured patientsCardiac resynchronization therapy defibrillatorPrivate insurancePropensity-weighted analysisSingle-chamber devicesPrimary preventionMean ageICD implantsPractice patternsTreatment weightingImplantation practicePatientsInverse probabilityTherapyInsurance coverageFurther studiesRegistryMedicareStatus
2020
Patient and hospital characteristics associated with ticagrelor uptake in acute MI: An analysis of the Chest Pain–MI Registry
Rodwin BA, Lu D, Giaimo A, Annapureddy A, Daggubati R, Curtis J, Sciria CT, Wang TY, Desai NR. Patient and hospital characteristics associated with ticagrelor uptake in acute MI: An analysis of the Chest Pain–MI Registry. International Journal Of Cardiology 2020, 304: 14-20. PMID: 31980270, DOI: 10.1016/j.ijcard.2020.01.029.Peer-Reviewed Original ResearchConceptsChest Pain-MI RegistryAcute myocardial infarctionTicagrelor useHospital characteristicsACC/AHA guidelinesUse of ticagrelorUse of clopidogrelHealth system performanceAHA guidelinesAcute MIHighest quartileAMI patientsInhibitor clopidogrelMI patientsMyocardial infarctionMultivariable modelWhite racePrasugrelPatientsTicagrelorHospitalPrivate insuranceClopidogrelP2YRegistry
2019
Quadripolar versus bipolar leads in cardiac resynchronization therapy: An analysis of the National Cardiovascular Data Registry
Hakemi EU, Doukky R, Parzynski CS, Curtis JP, Madias C. Quadripolar versus bipolar leads in cardiac resynchronization therapy: An analysis of the National Cardiovascular Data Registry. Heart Rhythm 2019, 17: 81-89. PMID: 31369870, DOI: 10.1016/j.hrthm.2019.07.028.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyNational Cardiovascular Data RegistryClinical outcomesResynchronization therapyData registryLong-term clinical outcomesStimulation rateSignificant differencesCongestive heart failure admissionsMedicaid ServicesCRT device implantsHeart failure admissionsProcedural complication rateCRT implantationElderly patientsComplication ratePrimary outcomePlacement failureDevice implantsDevice malfunctionOutcomesPatientsBipolar leadsRegistryTherapyValidating the use of registries and claims data to support randomized trials: Rationale and design of the Extending Trial-Based Evaluations of Medical Therapies Using Novel Sources of Data (EXTEND) Study
Strom JB, Tamez H, Zhao Y, Valsdottir LR, Curtis J, Brennan JM, Shen C, Popma JJ, Mauri L, Yeh RW. Validating the use of registries and claims data to support randomized trials: Rationale and design of the Extending Trial-Based Evaluations of Medical Therapies Using Novel Sources of Data (EXTEND) Study. American Heart Journal 2019, 212: 64-71. PMID: 30953936, PMCID: PMC6535119, DOI: 10.1016/j.ahj.2019.02.007.Peer-Reviewed Original ResearchConceptsMedical therapyDual Antiplatelet Therapy StudyEnd pointEnd-point eventsClinical trial programEfficacy of therapyPatient-level dataClinical trial dataHealth system dataUse of registriesNew medical treatmentsProcedural registryRandomized trialsClaims databasePatient populationNational registryAdministrative claimsOutcome dataMedical treatmentTrial programTrial dataRegistryTrial informationTherapy studiesTrial resultsUSE AND OUTCOMES OF DUAL CHAMBER AND CARDIAC RESYNCHRONIZATION THERAPY DEFIBRILLATORS AMONG OLDER PATIENTS UNDERGOING ICD IMPLANTATION WITH A VENTRICULAR PACING INDICATION: AN ANALYSIS OF THE NATIONAL CARDIOVASCULAR DATA ICD REGISTRY
Borne R, Bao H, Curtis J, Masoudi F, Zipse M, Sandhu A, Hsu J, Peterson P. USE AND OUTCOMES OF DUAL CHAMBER AND CARDIAC RESYNCHRONIZATION THERAPY DEFIBRILLATORS AMONG OLDER PATIENTS UNDERGOING ICD IMPLANTATION WITH A VENTRICULAR PACING INDICATION: AN ANALYSIS OF THE NATIONAL CARDIOVASCULAR DATA ICD REGISTRY. Journal Of The American College Of Cardiology 2019, 73: 389. DOI: 10.1016/s0735-1097(19)30997-0.Peer-Reviewed Original ResearchIMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY IN THE UNITED STATES: INSIGHTS FROM THE NCDR ICD REGISTRY, AN NCDR® RESEARCH TO PRACTICE (R2P) PROJECT
Kutyifa V, Bao H, Cha Y, Hsu J, Varosy P, Masoudi F, Curtis J, Peterson P. IMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY IN THE UNITED STATES: INSIGHTS FROM THE NCDR ICD REGISTRY, AN NCDR® RESEARCH TO PRACTICE (R2P) PROJECT. Journal Of The American College Of Cardiology 2019, 73: 311. DOI: 10.1016/s0735-1097(19)30919-2.Peer-Reviewed Original Research
2018
GUIDELINE-RECOMMENDED PATIENT EDUCATION AMONG OUTPATIENTS WITH HEART FAILURE: RESULTS FROM THE NCDR PINNACLE REGISTRY
Minges K, Spatz E, Brandt E, Song Y, Doros G, Cannon C, Cavanagh C, Rosman L, Curtis J, Desai N. GUIDELINE-RECOMMENDED PATIENT EDUCATION AMONG OUTPATIENTS WITH HEART FAILURE: RESULTS FROM THE NCDR PINNACLE REGISTRY. Journal Of The American College Of Cardiology 2018, 71: a1747. DOI: 10.1016/s0735-1097(18)32288-5.Peer-Reviewed Original ResearchAdoption of the transradial approach for percutaneous coronary intervention and rates of vascular complications following transfemoral procedures: Insights from NCDR
Badri M, Shapiro T, Wang Y, Minges KE, Curtis JP, Gray WA. Adoption of the transradial approach for percutaneous coronary intervention and rates of vascular complications following transfemoral procedures: Insights from NCDR. Catheterization And Cardiovascular Interventions 2018, 92: 835-841. PMID: 29359497, DOI: 10.1002/ccd.27490.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransfemoral percutaneous coronary interventionVascular complicationsTransradial approachCoronary interventionAccess site bleedingNCDR CathPCI RegistryFemoral operatorsTransfemoral proceduresRetroperitoneal bleedingCathPCI RegistrySite bleedingRetrospective analysisComplicationsPropensity scorePreadoption periodBleedingMeaningful increaseInterventionRecent studiesHematomaRegistryNCDRAccess skillsPhysicians
2017
Temporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads Data From the NCDR ICD Registry
Pokorney SD, Parzynski CS, Daubert JP, Hegland DD, Varosy PD, Curtis JP, Al-Khatib SM. Temporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads Data From the NCDR ICD Registry. JACC Clinical Electrophysiology 2017, 3: 612-619. PMID: 29759435, DOI: 10.1016/j.jacep.2016.11.014.Peer-Reviewed Original ResearchConceptsDual-coil ICD leadsICD RegistryNational Cardiovascular Data Registry ICD RegistryICD leadHospital-level factorsDual-coil leadsNCDR ICD RegistrySingle-coil leadsDual-coil ICDHigh-use groupPatient characteristicsPatient factorsPatient groupPatient outcomesImplantable cardioverterMore ICDsLower mortalityPre-specified groupsHospitalICDStatistical differenceUse of SingleTemporal trendsSignificant differencesRegistry
2016
Trends in U.S. Cardiovascular Care 2016 Report From 4 ACC National Cardiovascular Data Registries
Masoudi FA, Ponirakis A, de Lemos JA, Jollis JG, Kremers M, Messenger JC, Moore JWM, Moussa I, Oetgen WJ, Varosy PD, Vincent RN, Wei J, Curtis JP, Roe MT, Spertus JA. Trends in U.S. Cardiovascular Care 2016 Report From 4 ACC National Cardiovascular Data Registries. Journal Of The American College Of Cardiology 2016, 69: 1427-1450. PMID: 28025065, DOI: 10.1016/j.jacc.2016.12.005.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseAdult congenital heart diseaseNational Cardiovascular Data RegistryAcute coronary syndromePercutaneous coronary interventionCongenital heart diseaseOutcomes of careQuality of careMeasure of ProcessesCoronary syndromeClinical characteristicsCoronary interventionCardiac catheterizationHeart diseaseLeading causeData registryDiseaseCardiovascular dataPatientsRegistryBroader populationCareInterventionOutcomesReport
2015
Use of Mechanical Circulatory Support in Patients Undergoing Percutaneous Coronary Intervention
Sandhu A, McCoy LA, Negi SI, Hameed I, Atri P, Al'Aref SJ, Curtis J, McNulty E, Anderson HV, Shroff A, Menegus M, Swaminathan RV, Gurm H, Messenger J, Wang T, Bradley SM. Use of Mechanical Circulatory Support in Patients Undergoing Percutaneous Coronary Intervention. Circulation 2015, 132: 1243-1251. PMID: 26286905, DOI: 10.1161/circulationaha.114.014451.Peer-Reviewed Original ResearchConceptsIntra-aortic balloon pumpPercutaneous coronary interventionMechanical circulatory supportUse of IABPCardiogenic shockCirculatory supportCoronary interventionNational Cardiovascular Data Registry CathPCISetting of PCIStudy periodProportion of patientsHospital-level variationLarge national registryHalf of hospitalsBalloon pumpNational registryPatientsHospitalInterventionConcurrent increaseSettingTemporal trendsCathPCIRegistryContemporary use