2022
Temporal trends and long-term outcomes among recipients of cardiac resynchronization therapy with defibrillator in the United States, 2011–2015: Insights from the National Cardiovascular Data Registry
Darden D, Peterson PN, Xin X, Munir MB, Minges KE, Goldenberg I, Poole JE, Feld GK, Birgersdotter-Green U, Curtis JP, Hsu JC. Temporal trends and long-term outcomes among recipients of cardiac resynchronization therapy with defibrillator in the United States, 2011–2015: Insights from the National Cardiovascular Data Registry. Heart Rhythm O2 2022, 3: 405-414. PMID: 36097450, PMCID: PMC9463686, DOI: 10.1016/j.hroo.2022.03.004.Peer-Reviewed Original ResearchLong-term outcomesGuideline-concordant recommendationsHeart failure hospitalizationCardiac resynchronization therapyFailure hospitalizationCause hospitalizationCardiovascular hospitalizationResynchronization therapyNational Cardiovascular Data RegistryCRT-D implantationYear of implantHospital procedural complicationsHospital complicationsHospital outcomesMultivariable adjustmentPatient characteristicsProcedural complicationsDefibrillator recipientsHospitalizationData registryLower riskMedicare beneficiariesMedicare dataOutcomesRecipientsTrends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018
Borne RT, Varosy P, Lan Z, Masoudi FA, Curtis JP, Matlock DD, Peterson PN. Trends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018. JAMA Network Open 2022, 5: e223429. PMID: 35315917, PMCID: PMC8941353, DOI: 10.1001/jamanetworkopen.2022.3429.Peer-Reviewed Original ResearchConceptsDual-chamber ICDFirst-time ICD implantationPacing indicationICD implantationMedian odds ratioPatient characteristicsOdds ratioAtrial leadNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy indicationDual-chamber ICD implantationMulticenter cross-sectional studyBradycardia pacing indicationSingle-chamber ICDHospital-level variationHigh procedural riskCross-sectional studyLow-value practicesImplantable cardioverter defibrillatorLow-value careCochran-Armitage trend testImplantable cardioverter-defibrillator systemsDual-chamber devicesCardioverter-defibrillator systemsReal-world practice
2018
Ventricular Fibrillation Conversion Testing After Implantation of a Subcutaneous Implantable Cardioverter Defibrillator
Friedman DJ, Parzynski CS, Heist EK, Russo AM, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM. Ventricular Fibrillation Conversion Testing After Implantation of a Subcutaneous Implantable Cardioverter Defibrillator. Circulation 2018, 137: 2463-2477. PMID: 29463509, PMCID: PMC5988932, DOI: 10.1161/circulationaha.117.032167.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorS-ICD implantationLogistic regression analysisInhospital complicationsPatient characteristicsCT testingS-ICDsCardioverter defibrillatorConversion testingPrior implantable cardioverter defibrillatorHigher body mass indexMultivariable logistic regression analysisLarger body surface areaSubcutaneous implantable cardioverter defibrillatorTransvenous implantable cardioverter defibrillatorInhospital adverse eventsLow ejection fractionAvailable patient characteristicsBody mass indexBody surface areaFirst-time recipientsMaximum device outputRegression analysisPredictors of useInsufficient safety margin
2017
Modeling Major Adverse Outcomes of Pediatric and Adult Patients With Congenital Heart Disease Undergoing Cardiac Catheterization
Jayaram N, Spertus JA, Kennedy KF, Vincent R, Martin GR, Curtis JP, Nykanen D, Moore PM, Bergersen L. Modeling Major Adverse Outcomes of Pediatric and Adult Patients With Congenital Heart Disease Undergoing Cardiac Catheterization. Circulation 2017, 136: 2009-2019. PMID: 28882885, PMCID: PMC5698125, DOI: 10.1161/circulationaha.117.027714.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsBlood CoagulationBlood Coagulation DisordersCardiac CatheterizationChildChild, PreschoolChi-Square DistributionFemaleHeart Defects, CongenitalHemodynamicsHumansInfantInfant, NewbornKidneyLogistic ModelsMaleMultivariate AnalysisOdds RatioRegistriesRenal InsufficiencyReproducibility of ResultsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsProcedure-type risk categoriesMajor adverse outcomesMajor adverse eventsCardiac catheterizationCongenital heart diseaseAdverse eventsValidation cohortAdverse outcomesCongenital cardiac catheterizationIMPACT RegistryRisk categoriesHemodynamic vulnerabilityHeart diseaseMultivariable hierarchical logistic regression modelsFinal risk-adjustment modelSingle ventricle physiologyRisk-adjusted outcomesHierarchical logistic regression modelsRisk-adjustment modelsLogistic regression modelsRisk standardizationRenal insufficiencyAdult patientsConsecutive patientsPatient characteristicsTemporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads Data From the NCDR ICD Registry
Pokorney SD, Parzynski CS, Daubert JP, Hegland DD, Varosy PD, Curtis JP, Al-Khatib SM. Temporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads Data From the NCDR ICD Registry. JACC Clinical Electrophysiology 2017, 3: 612-619. PMID: 29759435, DOI: 10.1016/j.jacep.2016.11.014.Peer-Reviewed Original ResearchConceptsDual-coil ICD leadsICD RegistryNational Cardiovascular Data Registry ICD RegistryICD leadHospital-level factorsDual-coil leadsNCDR ICD RegistrySingle-coil leadsDual-coil ICDHigh-use groupPatient characteristicsPatient factorsPatient groupPatient outcomesImplantable cardioverterMore ICDsLower mortalityPre-specified groupsHospitalICDStatistical differenceUse of SingleTemporal trendsSignificant differencesRegistry
2016
Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study
Zheng X, Curtis JP, Hu S, Wang Y, Yang Y, Masoudi FA, Spertus JA, Li X, Li J, Dharmarajan K, Downing NS, Krumholz HM, Jiang L. Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study. JAMA Internal Medicine 2016, 176: 512. PMID: 26974883, PMCID: PMC5459379, DOI: 10.1001/jamainternmed.2016.0166.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngina, UnstableCardiac CatheterizationChinaCoronary Artery DiseaseDrug-Eluting StentsFemaleHospital MortalityHospitals, UrbanHumansLength of StayMaleMedical RecordsMiddle AgedMyocardial InfarctionOdds RatioOutcome Assessment, Health CarePercutaneous Coronary InterventionPostoperative ComplicationsPostoperative HemorrhageQuality of Health CareRetrospective StudiesStentsTime-to-TreatmentConceptsPercutaneous coronary interventionDrug-eluting stentsQuality of careCoronary catheterizationCoronary interventionNonobstructive coronary artery diseasePrimary percutaneous coronary interventionFuture quality improvement initiativesEvidence-based medicationsOutcomes of patientsCoronary artery diseaseClinical observational studyUse of catheterizationQuality improvement initiativesCalendar year 2001Hospital mortalityArtery diseasePatient characteristicsStable patientsTreatment patternsMedian lengthMean agePCI proceduresMedical recordsObservational study
2015
Association of Physician Certification in Interventional Cardiology With In-Hospital Outcomes of Percutaneous Coronary Intervention
Fiorilli PN, Minges KE, Herrin J, Messenger JC, Ting HH, Nallamothu BK, Lipner RS, Hess BJ, Holmboe ES, Brennan JJ, Curtis JP. Association of Physician Certification in Interventional Cardiology With In-Hospital Outcomes of Percutaneous Coronary Intervention. Circulation 2015, 132: 1816-1824. PMID: 26384518, PMCID: PMC4641797, DOI: 10.1161/circulationaha.115.017523.Peer-Reviewed Original ResearchConceptsEmergency coronary artery bypassPercutaneous coronary interventionCoronary artery bypassArtery bypassVascular complicationsHospital mortalityEnd pointHospital outcomesCoronary interventionPCI proceduresIn-Hospital OutcomesPrimary end pointSecondary end pointsComposite end pointRisk of bleedingHierarchical multivariable modelInternal Medicine certificationAmerican BoardCathPCI RegistryPatient characteristicsPCI volumeUnadjusted outcomesAdverse outcomesPatient outcomesMultivariable modelPercutaneous Coronary Intervention Utilization and Appropriateness across the United States
Thomas MP, Parzynski CS, Curtis JP, Seth M, Nallamothu BK, Chan PS, Spertus JA, Patel MR, Bradley SM, Gurm HS. Percutaneous Coronary Intervention Utilization and Appropriateness across the United States. PLOS ONE 2015, 10: e0138251. PMID: 26379053, PMCID: PMC4575022, DOI: 10.1371/journal.pone.0138251.Peer-Reviewed Original ResearchConceptsAppropriate use criteriaHospital referral regionsPCI utilizationQuintile 5PCI ratesQuintiles 1PCI appropriatenessPercutaneous coronary intervention useMedicare Limited Data SetRisk-adjusted mortalityNCDR CathPCI RegistryElective PCICathPCI RegistryInappropriate indicationsPatient characteristicsStudy cohortAppropriate indicationsPCI proceduresHeart AssociationCardiovascular AngiographyStudy populationAmerican CollegeReferral regionsSubstantial geographic variationIntervention utilizationDefibrillator implantations for primary prevention in the United States: Inappropriate care or inadequate documentation: Insights from the National Cardiovascular Data ICD Registry
Kaiser DW, Tsai V, Heidenreich PA, Goldstein MK, Wang Y, Curtis J, Turakhia MP, Registry C. Defibrillator implantations for primary prevention in the United States: Inappropriate care or inadequate documentation: Insights from the National Cardiovascular Data ICD Registry. Heart Rhythm 2015, 12: 2086-2093. PMID: 25982720, PMCID: PMC4770888, DOI: 10.1016/j.hrthm.2015.05.010.Peer-Reviewed Original ResearchConceptsMulticenter Unsustained Tachycardia TrialMulticenter Automatic Defibrillator Implantation TrialICD RegistryPrimary preventionICD implantationInclusion criteriaNational Cardiovascular Data Registry ICD RegistryMultivariate analysisImplantable cardioverter defibrillator implantationAtrioventricular conduction diseaseFirst-time ICDPrimary prevention ICDsPrior cardiac transplantationHeart Failure TrialPrimary prevention trialsProportion of patientsCardioverter-defibrillator implantationAppropriate use criteriaSudden cardiac deathCardiac transplantationDefibrillator implantationMADIT-IIPatient characteristicsYounger patientsCardiac deathState Mandated Public Reporting and Outcomes of Percutaneous Coronary Intervention in the United States
Cavender MA, Joynt KE, Parzynski CS, Resnic FS, Rumsfeld JS, Moscucci M, Masoudi FA, Curtis JP, Peterson ED, Gurm HS. State Mandated Public Reporting and Outcomes of Percutaneous Coronary Intervention in the United States. The American Journal Of Cardiology 2015, 115: 1494-1501. PMID: 25891991, PMCID: PMC6948713, DOI: 10.1016/j.amjcard.2015.02.050.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionHospital mortalityCoronary interventionPublic reportingMost percutaneous coronary interventionsOutcomes of patientsReporting statesMandatory public reportingHealth care qualityCathPCI RegistryHospital readmissionPatient characteristicsMyocardial infarctionPatientsObserved riskCare qualityMortalityOutcomesFurther studiesPotential strategyInterventionUnited StatesRiskDaysReporting
2014
Temporal Trends in Patient Characteristics and Outcomes Among Medicare Beneficiaries Undergoing Primary Prevention Implantable Cardioverter-Defibrillator Placement in the United States, 2006–2010
Borne RT, Peterson PN, Greenlee R, Heidenreich PA, Wang Y, Curtis JP, Tzou WS, Varosy PD, Kremers MS, Masoudi FA. Temporal Trends in Patient Characteristics and Outcomes Among Medicare Beneficiaries Undergoing Primary Prevention Implantable Cardioverter-Defibrillator Placement in the United States, 2006–2010. Circulation 2014, 130: 845-853. PMID: 25095884, DOI: 10.1161/circulationaha.114.008653.Peer-Reviewed Original ResearchConceptsPrimary prevention ICD implantationDevice-related complicationsPatient characteristicsICD implantationICD RegistryNational Cardiovascular Data Registry ICD RegistryPrimary prevention implantable cardioverter-defibrillator placementConcomitant cardiac resynchronization therapyLeft ventricular ejection fractionImplantable cardioverter-defibrillator placementMultivariable hierarchical logistic regressionCardiac resynchronization therapy devicesCardiac resynchronization therapyVentricular ejection fractionResynchronization therapy devicesCommunity practice settingsSingle-lead deviceHierarchical logistic regressionClinical characteristicsOlder patientsEjection fractionResynchronization therapyPrimary preventionPatient populationHospital characteristicsIn-Hospital Complications Associated With Reoperations of Implantable Cardioverter Defibrillators
Steckman DA, Varosy PD, Parzynski CS, Masoudi FA, Curtis JP, Sauer WH, Nguyen DT. In-Hospital Complications Associated With Reoperations of Implantable Cardioverter Defibrillators. The American Journal Of Cardiology 2014, 114: 419-426. PMID: 24927972, DOI: 10.1016/j.amjcard.2014.05.010.Peer-Reviewed Original ResearchConceptsHospital complicationsComplication rateRepeat proceduresLead extractionICD proceduresMultivariable adjusted odds ratiosNational Cardiovascular Data RegistryInitial implantImplantable cardioverter-defibrillator (ICD) proceduresHierarchical multivariable logistic regressionHospital adverse eventsAdjusted odds ratioHigh complication rateMultivariable logistic regressionLarge national cohortImplantable cardioverter defibrillatorHospital deathAdverse eventsICD implantationPatient characteristicsNational cohortOdds ratioProcedural outcomesCardioverter defibrillatorHigh risk
2013
Determinants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention: Insights from the NCDR®
Fazel R, Curtis J, Wang Y, Einstein AJ, Smith‐Bindman R, Tsai TT, Chen J, Shah ND, Krumholz HM, Nallamothu BK. Determinants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention: Insights from the NCDR®. Catheterization And Cardiovascular Interventions 2013, 82: 1091-1105. PMID: 23703793, DOI: 10.1002/ccd.24996.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionInvasive coronary angiographyHospital-level factorsFluoroscopy timePrior CABGCoronary interventionPrior coronary artery bypassRadiation exposureCoronary artery bypassNumerous clinical scenariosArtery bypassCathPCI RegistryPatient characteristicsCoronary angiographyPCI proceduresModifiable determinantsPatientsClinical scenariosModifiable sourceProcedure complexityCABGMinutesInterventionExposureWide variation
2011
Physician Procedure Volume and Complications of Cardioverter-Defibrillator Implantation
Freeman JV, Wang Y, Curtis JP, Heidenreich PA, Hlatky MA. Physician Procedure Volume and Complications of Cardioverter-Defibrillator Implantation. Circulation 2011, 125: 57-64. PMID: 22095828, DOI: 10.1161/circulationaha.111.046995.Peer-Reviewed Original ResearchConceptsPhysician procedure volumeProcedure volumeHospital mortalityICD implantationHospital characteristicsPhysician specialtyNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator placementInitial ICD implantationRate of complicationsCardioverter-defibrillator implantationHospital procedure volumeClustering of patientsAnnual procedure volumeOutcomes of proceduresVolume of proceduresHierarchical logistic regressionHospital complicationsComplication rateHospital volumePatient characteristicsProcedural complicationsHighest quartileInverse relationshipComplications
2006
Effect of Door-to-Balloon Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
McNamara RL, Wang Y, Herrin J, Curtis JP, Bradley EH, Magid DJ, Peterson ED, Blaney M, Frederick PD, Krumholz HM, Investigators N. Effect of Door-to-Balloon Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction. Journal Of The American College Of Cardiology 2006, 47: 2180-2186. PMID: 16750682, DOI: 10.1016/j.jacc.2005.12.072.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionBalloon timeElevation myocardial infarctionSymptom onsetMyocardial infarctionHospital mortalityPatient characteristicsDoor timeEffect of doorPrimary PCIBaseline risk statusPercutaneous coronary interventionHigh-risk factorsSTEMI patientsCohort studyCoronary interventionLonger doorEntire cohortSubgroup analysisNational registryBaseline riskMortality riskPatientsMortality