2018
Outcomes following implantable cardioverter-defibrillator generator replacement in patients with recovered left ventricular systolic function: The National Cardiovascular Data Registry
Thomas IC, Wang Y, See VY, Minges KE, Curtis JP, Hsu JC. Outcomes following implantable cardioverter-defibrillator generator replacement in patients with recovered left ventricular systolic function: The National Cardiovascular Data Registry. Heart Rhythm 2018, 16: 733-740. PMID: 30414460, DOI: 10.1016/j.hrthm.2018.11.005.Peer-Reviewed Original ResearchConceptsLV ejection fractionNational Cardiovascular Data Registry ICD RegistryReduced LV ejection fractionICD generator replacementLeft ventricular systolic functionVentricular systolic functionHF readmissionSystolic functionGenerator replacementAdverse outcomesImplantable Cardioverter-Defibrillator Generator ReplacementNational Cardiovascular Data RegistryLV systolic functionEjection fractionICD RegistryPeriprocedural eventsPrognostic associationAmerican CollegeHigh riskData registryLower riskMedicare beneficiariesPatientsReadmissionClinical encounters
2003
Association of Serum Digoxin Concentration and Outcomes in Patients With Heart Failure
Rathore SS, Curtis JP, Wang Y, Bristow MR, Krumholz HM. Association of Serum Digoxin Concentration and Outcomes in Patients With Heart Failure. JAMA 2003, 289: 871-878. PMID: 12588271, DOI: 10.1001/jama.289.7.871.Peer-Reviewed Original ResearchConceptsSerum digoxin concentrationHigh serum digoxin concentrationsLeft ventricular ejection fractionVentricular ejection fractionHeart failureMortality rateDIG trialDigoxin therapyEjection fractionDigoxin concentrationsDepressed left ventricular systolic functionDigitalis Investigation Group trialHigher absolute mortality rateLeft ventricular systolic functionOverall mortality benefitVentricular systolic functionCause mortality ratesAbsolute mortality ratesLower mortality rateCause mortalityMultivariable adjustmentMortality benefitSystolic functionClinical outcomesSerum concentrations