2022
Longitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients
Friedman DJ, Qin L, Parzynski C, Heist EK, Russo AM, Ranasinghe I, Zeitler EP, Minges KE, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM. Longitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients. Journal Of The American College Of Cardiology 2022, 79: 1050-1059. PMID: 35300816, DOI: 10.1016/j.jacc.2021.12.033.Peer-Reviewed Original ResearchConceptsOlder patientsCause readmissionS-ICDNational Cardiovascular Data Registry ICD RegistryDevice removalTransvenous implantable cardioverter defibrillatorTV-ICD patientsRisk of deathS-ICD patientsService Medicare beneficiariesAnderson-Gill modelsImplantable cardioverter defibrillatorRepresentative national cohortCompeting-risks modelTV-ICDCardiovascular readmissionCause mortalityICD implantationYounger patientsICD RegistryNonfatal outcomesTransvenous ICDAtrial fibrillationNational cohortCardioverter defibrillatorTrends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018
Borne RT, Varosy P, Lan Z, Masoudi FA, Curtis JP, Matlock DD, Peterson PN. Trends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018. JAMA Network Open 2022, 5: e223429. PMID: 35315917, PMCID: PMC8941353, DOI: 10.1001/jamanetworkopen.2022.3429.Peer-Reviewed Original ResearchConceptsDual-chamber ICDFirst-time ICD implantationPacing indicationICD implantationMedian odds ratioPatient characteristicsOdds ratioAtrial leadNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy indicationDual-chamber ICD implantationMulticenter cross-sectional studyBradycardia pacing indicationSingle-chamber ICDHospital-level variationHigh procedural riskCross-sectional studyLow-value practicesImplantable cardioverter defibrillatorLow-value careCochran-Armitage trend testImplantable cardioverter-defibrillator systemsDual-chamber devicesCardioverter-defibrillator systemsReal-world practice
2021
Risk and predictors of mortality after implantable cardioverter-defibrillator implantation in patients with sarcoid cardiomyopathy
Higgins AY, Annapureddy AR, Wang Y, Minges KE, Bellumkonda L, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Risk and predictors of mortality after implantable cardioverter-defibrillator implantation in patients with sarcoid cardiomyopathy. American Heart Journal 2021, 246: 21-31. PMID: 34968442, DOI: 10.1016/j.ahj.2021.12.011.Peer-Reviewed Original ResearchConceptsNon-ischemic cardiomyopathyAtrial fibrillation/flutterChronic lung diseaseCardiac sarcoidosisHeart failureCS patientsNICM patientsICD implantationLung diseaseNew York Heart Association class III heart failureNational Cardiovascular Data Registry ICD RegistryNYHA class IV heart failureClass III heart failureClass IV heart failureImplantable cardioverter defibrillator implantationKaplan-Meier survival curvesCox proportional hazards modelPredictors of mortalityCardioverter-defibrillator implantationVentricular ejection fractionMultivariable logistic regressionPrior ventricular arrhythmiasProportional hazards modelRate of deathTime of implantationTrends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation
Bourdillon PM, Parzynski CS, Minges KE, Curtis JP, Desai NR. Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation. Journal Of Cardiac Failure 2021, 28: 154-160. PMID: 34628015, DOI: 10.1016/j.cardfail.2021.09.010.Peer-Reviewed Original ResearchConceptsHospital adverse eventsHospital outcomesAdverse eventsHeart failureMyocardial infarctionRecent acute myocardial infarctionPlacement of ICDsPrimary prevention ICDsAdverse event ratesRecent myocardial infarctionAcute myocardial infarctionHigh mortality rateICD implantationRecent diagnosisMortality ratePatientsICDInfarctionHospitalOutcomesRapid reductionUse of devicesFailureSpecific reasonsCriteriaLongitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry)
Daimee UA, Aslam F, Parzynski CS, Desai NR, Curtis JP. Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry). The American Journal Of Cardiology 2021, 155: 64-71. PMID: 34315569, DOI: 10.1016/j.amjcard.2021.06.020.Peer-Reviewed Original ResearchConceptsPrimary prevention ICD implantationRisk of mortalityICD implantationHeart failureICD RegistryMortality riskNational Cardiovascular Data Registry ICD RegistryPivotal randomized clinical trialsHospital adverse eventsSevere heart failureRecent myocardial infarctionCause hospital readmissionRandomized clinical trialsSimilar mortality riskLongitudinal outcomesImplantable cardioverter defibrillatorGreater mortality riskCause hospitalizationCause mortalityCoronary revascularizationAdverse eventsHospital readmissionICD recipientsDevice implantationPrimary prevention
2020
Association Between Industry Payments to Physicians and Device Selection in ICD Implantation
Annapureddy AR, Henien S, Wang Y, Minges KE, Ross JS, Spatz ES, Desai NR, Peterson PN, Masoudi FA, Curtis JP. Association Between Industry Payments to Physicians and Device Selection in ICD Implantation. JAMA 2020, 324: 1755-1764. PMID: 33141208, PMCID: PMC7610190, DOI: 10.1001/jama.2020.17436.Peer-Reviewed Original ResearchConceptsCRT-D implantationCRT-D devicesCross-sectional studyNational Cardiovascular Data Registry ICD RegistryFirst-time ICDFirst-time implantationProportion of patientsEntire study cohortDevice selectionProportion of devicesICD implantationICD RegistryPrimary outcomeCardiac resynchronizationStudy cohortPatient groupMAIN OUTCOMEPatientsPhysiciansICDAbsolute differenceImplantationManufacturer CHigher total paymentsAssociationMortality and readmission in non-ischemic compared with ischemic cardiomyopathies after implantable cardioverter-defibrillator implantation
Freeman J, Bjerre J, Parzynski C, Minges K, Ahmad T, Desai N, Enriquez A, Spatz E, Friedman D, Curtis J, Hlatky M, Higgins A. Mortality and readmission in non-ischemic compared with ischemic cardiomyopathies after implantable cardioverter-defibrillator implantation. European Heart Journal 2020, 41: ehaa946.0788. DOI: 10.1093/ehjci/ehaa946.0788.Peer-Reviewed Original ResearchNon-ischemic cardiomyopathyImplantable cardioverter defibrillator implantationPrimary prevention ICDsCardioverter-defibrillator implantationIschemic cardiomyopathyICM patientsNational Cardiovascular Data Registry ICD RegistryCox proportional hazards regression modelPrimary prevention ICD implantationLeft ventricular ejection fractionProportional hazards regression modelsOne-year mortalityHeart failure readmissionVentricular ejection fractionKaplan-Meier curvesHazards regression modelsRisk of mortalityMedian followCause readmissionICD implantationEjection fractionHeart failureHospital readmissionICD RegistryPatient subgroupsSurvival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy
Higgins AY, Annapureddy AR, Wang Y, Minges KE, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Survival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016038. PMID: 32867553, PMCID: PMC7726970, DOI: 10.1161/jaha.120.016038.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationNonischemic cardiomyopathyCardiac amyloidosisDiabetes mellitusCerebrovascular diseaseVentricular tachycardiaMultivariable Cox proportional hazards regression modelsCox proportional hazards regression modelProportional hazards regression modelsKaplan-Meier survival curvesCox proportional hazards modelPropensity-matched cohortOutcomes of patientsHazards regression modelsProportional hazards modelCause mortalityICD implantationRenal functionMultivariable analysisConclusions MortalityRisk factorsRegistry dataAmyloid cardiomyopathyHigh riskComparison of Mortality and Readmission in Non-Ischemic Versus Ischemic Cardiomyopathy After Implantable Cardioverter-Defibrillator Implantation
Higgins AY, Bjerre J, Parzynski CS, Minges KE, Ahmad T, Desai NR, Enriquez A, Spatz ES, Friedman DJ, Curtis JP, Hlatky MA, Freeman JV. Comparison of Mortality and Readmission in Non-Ischemic Versus Ischemic Cardiomyopathy After Implantable Cardioverter-Defibrillator Implantation. The American Journal Of Cardiology 2020, 133: 116-125. PMID: 32862971, DOI: 10.1016/j.amjcard.2020.07.035.Peer-Reviewed Original ResearchConceptsNon-ischemic cardiomyopathyImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationICM patientsIschemic cardiomyopathyNational Cardiovascular Data Registry ICD RegistryCox proportional hazards regression modelPrimary prevention ICD implantationLeft ventricular ejection fractionProportional hazards regression modelsPrimary prevention ICDsRetrospective cohort studyVentricular ejection fractionKaplan-Meier curvesHazards regression modelsRisk of mortalityComparison of mortalityMedian followCohort studyICD implantationEjection fractionHeart failureHospital readmissionICD RegistryPatient subgroupsPrevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Prevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR. International Journal Of Cardiology 2020, 305: 44-49. PMID: 31980272, DOI: 10.1016/j.ijcard.2020.01.027.Peer-Reviewed Original ResearchConceptsInadequate defibrillation safety marginDefibrillation safety marginDFT testingDefibrillation threshold testingHospital complicationsPediatric patientsHospital stayICD recipientsNational Cardiovascular Data Registry ICD RegistryThreshold testingLowest successful energyProlonged hospital stayRisk of complicationsTransvenous ICD implantationHospital dischargeICD implantationMultivariable adjustmentICD RegistryPediatric populationRetrospective analysisLower oddsComplicationsPatientsTesting useLittle data
2019
Analysis of Temporal Trends and Variation in the Use of Defibrillation Testing in Contemporary Practice
Borne RT, Randolph T, Wang Y, Curtis JP, Peterson PN, Masoudi FA, Sandhu A, Zipse MM, Thomas K, Kutyifa V, Desai NR, Cha YM, Hsu JC, Russo AM. Analysis of Temporal Trends and Variation in the Use of Defibrillation Testing in Contemporary Practice. JAMA Network Open 2019, 2: e1913553. PMID: 31626314, PMCID: PMC6813586, DOI: 10.1001/jamanetworkopen.2019.13553.Peer-Reviewed Original ResearchConceptsNational Cardiovascular Data Registry ICD RegistryMedian odds ratioDefibrillation testingLow testing ratesTesting ratesHigher testing ratesICD RegistryFirst-time ICD implantationImplantable cardioverter defibrillator implantationMulticenter cross-sectional studyAdvanced heart failureCardioverter-defibrillator implantationIschemic heart diseaseCross-sectional studyICD implantationHeart failureICD placementVentricular arrhythmiasMean ageHeart diseaseVentricular tachycardiaOdds ratioHigher oddsMAIN OUTCOMEFirst calendar quarterAssociation of Physician Specialty With Long-Term Implantable Cardioverter-Defibrillator Complication and Reoperations Rates
Chui PW, Wang Y, Ranasinghe I, Mitiku TY, Seto AH, Rosman L, Lampert R, Minges KE, Enriquez AD, Curtis JP. Association of Physician Specialty With Long-Term Implantable Cardioverter-Defibrillator Complication and Reoperations Rates. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005374. PMID: 31185734, PMCID: PMC7412734, DOI: 10.1161/circoutcomes.118.005374.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overClinical CompetenceDefibrillators, ImplantableElectric CountershockFee-for-Service PlansFemaleHumansIncidenceMaleMedicarePostoperative ComplicationsPractice Patterns, Physicians'RegistriesReoperationRisk AssessmentRisk FactorsSpecializationTime FactorsTreatment OutcomeUnited StatesConceptsLong-term device-related complicationsDevice-related complicationsICD implantationLong-term outcomesPhysician specialtyGeneral cardiologistsThoracic surgeonsHigh riskNational Cardiovascular Data Registry ICD RegistryLong-term adverse outcomesImplantable cardioverter defibrillator implantationPhysician specialty trainingCardioverter-defibrillator implantationCumulative incidence rateCase-mix adjusted ratesReoperation rateBackground PatientsConclusions PatientsICD RegistryPrimary outcomeAdverse outcomesIncidence rateInterventional cardiologistsAdjusted ratesReoperation
2017
Long-term morbidity and mortality after implantable cardioverter-defibrillator implantation with procedural complication: A report from the National Cardiovascular Data Registry
Kipp R, Hsu JC, Freeman J, Curtis J, Bao H, Hoffmayer KS. Long-term morbidity and mortality after implantable cardioverter-defibrillator implantation with procedural complication: A report from the National Cardiovascular Data Registry. Heart Rhythm 2017, 15: 847-854. PMID: 28987459, DOI: 10.1016/j.hrthm.2017.09.043.Peer-Reviewed Original ResearchConceptsCause mortalityMedicare beneficiariesICD implantationProcedural complicationsHospital characteristicsMultivariable Cox proportional hazards regression analysisNational Cardiovascular Data Registry ICD RegistryCox proportional hazards regression analysisFirst-time ICD recipientsImplantable cardioverter defibrillator implantationNational Cardiovascular Data RegistryProportional hazards regression analysisKaplan-Meier survival analysisLong-term morbidityPredictors of mortalityCardioverter-defibrillator implantationOccurrence of complicationsRetrospective registry studyAcute procedural complicationsHazards regression analysisLong-term outcomesRisk of mortalityMortality 3 yearsIndex hospitalizationRegistry study
2016
Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States
Friedman DJ, Parzynski CS, Varosy PD, Prutkin JM, Patton KK, Mithani A, Russo AM, Curtis JP, Al-Khatib SM. Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States. JAMA Cardiology 2016, 1: 900-911. PMID: 27603935, PMCID: PMC5112106, DOI: 10.1001/jamacardio.2016.2782.Peer-Reviewed Original ResearchConceptsSubcutaneous implantable cardioverter defibrillatorPropensity-matched analysisS-ICDHospital outcomesImplantable cardioverter defibrillatorICD implantsComplication rateICD RegistryDFT testingS-ICDsCardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryHospital complication ratesIn-Hospital OutcomesPrior cardiac arrestLow complication rateS-ICD implantationUse of ICDsSC-ICDICD implantationCardiac arrestMean ageRetrospective analysisMAIN OUTCOMEPatientsLong-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation: An Observational Cohort Study.
Ranasinghe I, Parzynski CS, Freeman JV, Dreyer RP, Ross JS, Akar JG, Krumholz HM, Curtis JP. Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation: An Observational Cohort Study. Annals Of Internal Medicine 2016, 165: 20-29. PMID: 27135392, DOI: 10.7326/m15-2732.Peer-Reviewed Original ResearchICD-related complicationsNational Cardiovascular Data RegistryObservational cohort studyDevice-related complicationsICD implantationLong-term riskCohort studyMedicare feeNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter defibrillator implantationImplantable cardioverter-defibrillator placementCardioverter-defibrillator implantationService claims dataCRT-D devicesSingle-chamber devicesCumulative incidenceNonfatal outcomesICD RegistryService patientsBlack raceFemale sexReoperationAmerican CollegeClaims dataComplications
2015
Does Age Influence Cardiac Resynchronization Therapy Use and Outcome?
Heidenreich PA, Tsai V, Bao H, Curtis J, Goldstein M, Curtis L, Hernandez A, Peterson P, Turakhia MP, Masoudi FA. Does Age Influence Cardiac Resynchronization Therapy Use and Outcome? JACC Heart Failure 2015, 3: 497-504. PMID: 25982109, DOI: 10.1016/j.jchf.2015.01.012.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionICD implantationOlder patientsTrial criteriaNew York Heart Association functional class IIIAge groupsSocial Security Death IndexPatients age 85Receipt of CRTFunctional class IIICardiac resynchronization therapyVentricular ejection fractionClinical trial criteriaDifferent age groupsPatient ageEjection fractionICD RegistryImproved survivalPrimary outcomeResynchronization therapyTherapy useDeath IndexMean ageClinical trialsRegistry dataDefibrillator implantations for primary prevention in the United States: Inappropriate care or inadequate documentation: Insights from the National Cardiovascular Data ICD Registry
Kaiser DW, Tsai V, Heidenreich PA, Goldstein MK, Wang Y, Curtis J, Turakhia MP, Registry C. Defibrillator implantations for primary prevention in the United States: Inappropriate care or inadequate documentation: Insights from the National Cardiovascular Data ICD Registry. Heart Rhythm 2015, 12: 2086-2093. PMID: 25982720, PMCID: PMC4770888, DOI: 10.1016/j.hrthm.2015.05.010.Peer-Reviewed Original ResearchConceptsMulticenter Unsustained Tachycardia TrialMulticenter Automatic Defibrillator Implantation TrialICD RegistryPrimary preventionICD implantationInclusion criteriaNational Cardiovascular Data Registry ICD RegistryMultivariate analysisImplantable cardioverter defibrillator implantationAtrioventricular conduction diseaseFirst-time ICDPrimary prevention ICDsPrior cardiac transplantationHeart Failure TrialPrimary prevention trialsProportion of patientsCardioverter-defibrillator implantationAppropriate use criteriaSudden cardiac deathCardiac transplantationDefibrillator implantationMADIT-IIPatient characteristicsYounger patientsCardiac deathGender and outcomes after primary prevention implantable cardioverter-defibrillator implantation: Findings from the National Cardiovascular Data Registry (NCDR)
Russo AM, Daugherty SL, Masoudi FA, Wang Y, Curtis J, Lampert R. Gender and outcomes after primary prevention implantable cardioverter-defibrillator implantation: Findings from the National Cardiovascular Data Registry (NCDR). American Heart Journal 2015, 170: 330-338. PMID: 26299231, PMCID: PMC4768728, DOI: 10.1016/j.ahj.2015.02.025.Peer-Reviewed Original ResearchConceptsNational Cardiovascular Data RegistryPrimary preventionHF readmissionCause readmissionHospital dischargeICD implantationHeart failurePrimary prevention implantable cardioverter-defibrillator (ICD) implantationDual-chamber ICD implantationImplantable cardioverter defibrillator implantationPatients 65 yearsAdvanced heart failureProcedure-related complicationsCardioverter-defibrillator implantationDevice-related complicationsSudden cardiac deathHigh-risk individualsDual-chamber ICDGreater comorbidityBaseline characteristicsOlder patientsCardiac deathProcedural complicationsWorse outcomesClinical trialsAntithrombotic Therapy and Outcomes After ICD Implantation in Patients With Atrial Fibrillation and Coronary Artery Disease: An Analysis From the National Cardiovascular Data Registry (NCDR)®
Ghanbari H, Nallamothu BK, Wang Y, Curtis JP. Antithrombotic Therapy and Outcomes After ICD Implantation in Patients With Atrial Fibrillation and Coronary Artery Disease: An Analysis From the National Cardiovascular Data Registry (NCDR)®. Journal Of The American Heart Association 2015, 4: e001331. PMID: 25637345, PMCID: PMC4345865, DOI: 10.1161/jaha.114.001331.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCoronary Artery DiseaseDefibrillators, ImplantableDrug Therapy, CombinationFemaleFibrinolytic AgentsHemorrhageHumansIncidenceMaleMedicareMiddle AgedPatient DischargePlatelet Aggregation InhibitorsRegistriesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesWarfarinConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationCoronary artery diseaseMajor adverse cardiovascular eventsNational Cardiovascular Data RegistryAdverse cardiovascular eventsDevice-related complicationsAntithrombotic agentsDefibrillator implantationArtery diseaseAtrial fibrillationAntithrombotic therapyBleeding riskCardiovascular eventsThromboembolic eventsNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryImplantable Cardioverter-Defibrillator RegistryHigh bleeding riskCombination of DAHospital dischargeICD implantationPrimary outcomeData registryPatientsFibrillationA validated risk model for 1-year mortality after primary prevention implantable cardioverter defibrillator placement
Heidenreich PA, Tsai V, Curtis J, Wang Y, Turakhia MP, Masoudi FA, Varosy PD, Goldstein MK. A validated risk model for 1-year mortality after primary prevention implantable cardioverter defibrillator placement. American Heart Journal 2015, 170: 281-289.e2. PMID: 26299225, DOI: 10.1016/j.ahj.2014.12.013.Peer-Reviewed Original ResearchConceptsOne-year mortalityImplantable cardioverter defibrillatorRisk factorsHeart failurePrimary preventionMortality riskRisk scorePrimary prevention implantable cardioverter-defibrillator placementB-type natriuretic peptide valuesImplantable cardioverter-defibrillator placementCardiovascular Disease RegistryPrimary prevention populationNatriuretic peptide valuesChronic lung diseaseSystolic blood pressureSimilar risk factorsBlood urea nitrogenPg/mLLogistic regression modelsPrevention populationICD therapyICD implantationBlood pressureICD RegistryICD placement