2023
Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures
Hsu J, Darden D, Du C, Marine J, Nichols S, Marcus G, Natale A, Noseworthy P, Selzman K, Varosy P, Masoudi F, Freeman J, Curtis J, Akar J, Kowey P. Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures. Journal Of The American College Of Cardiology 2023, 81: 867-878. PMID: 36858707, DOI: 10.1016/j.jacc.2022.11.060.Peer-Reviewed Original ResearchConceptsAtrial fibrillation ablation proceduresAblation RegistryHospital outcomesAblation proceduresSuccessful pulmonary vein isolationNational Cardiovascular Data RegistryOutcomes of patientsProspective cohort studyMajority of patientsPulmonary vein isolationEvidence-based guidelinesDifferent patient outcomesReal-world prevalenceProcedural admissionsHospital deathAF ablationCohort studyPericardial effusionVein isolationHeart failureLarge multicenterMajor complicationsCatheter ablationTreatment patternsPatient population
2022
Comparative Safety of Transcatheter LAAO With the First-Generation Watchman and Next-Generation Watchman FLX Devices
Price M, Friedman D, Du C, Wang Y, Lin Z, Curtis J, Freeman J. Comparative Safety of Transcatheter LAAO With the First-Generation Watchman and Next-Generation Watchman FLX Devices. JACC Cardiovascular Interventions 2022, 15: 2115-2123. PMID: 36357014, DOI: 10.1016/j.jcin.2022.09.002.Peer-Reviewed Original ResearchConceptsHospital major adverse eventsMajor adverse eventsWatchman FLXMajor vascular complicationsMajor bleedingPericardial effusionCardiac arrestDevice embolizationVascular complicationsMyocardial infarctionLower ratesSystemic arterial embolismComposite of deathTransient ischemic attackAtrial appendage occlusionSignificant lower rateBalance of risksHospital mortalityIschemic attackArterial embolismHospital outcomesPrimary endpointStroke preventionAdverse eventsProcedural complicationsIn-hospital outcomes and readmission in older adults treated with percutaneous coronary intervention for stable ischemic heart disease
Park DY, Hanna JM, Kadian S, Kadian M, Jones WS, Damluji AA, Kochar A, Curtis JP, Nanna MG. In-hospital outcomes and readmission in older adults treated with percutaneous coronary intervention for stable ischemic heart disease. Journal Of Geriatric Cardiology 2022, 19: 631-642. PMID: 36284680, PMCID: PMC9548058, DOI: 10.11909/j.issn.1671-5411.2022.09.006.Peer-Reviewed Original ResearchStable ischemic heart diseasePercutaneous coronary interventionInpatient percutaneous coronary interventionIschemic heart diseaseHospital mortalityOlder adultsIndex hospitalizationCoronary interventionHospital chargesHeart diseaseNational Readmission DatabaseTotal hospital chargesHigh-risk cohortOlder adult patientsPeriprocedural morbidityCardiovascular causesGastrointestinal hemorrhageHospital lengthHospital outcomesAdult patientsSecondary outcomesLonger LOSPrimary outcomeIntracranial hemorrhageProcedural riskTemporal trends and long-term outcomes among recipients of cardiac resynchronization therapy with defibrillator in the United States, 2011–2015: Insights from the National Cardiovascular Data Registry
Darden D, Peterson PN, Xin X, Munir MB, Minges KE, Goldenberg I, Poole JE, Feld GK, Birgersdotter-Green U, Curtis JP, Hsu JC. Temporal trends and long-term outcomes among recipients of cardiac resynchronization therapy with defibrillator in the United States, 2011–2015: Insights from the National Cardiovascular Data Registry. Heart Rhythm O2 2022, 3: 405-414. PMID: 36097450, PMCID: PMC9463686, DOI: 10.1016/j.hroo.2022.03.004.Peer-Reviewed Original ResearchLong-term outcomesGuideline-concordant recommendationsHeart failure hospitalizationCardiac resynchronization therapyFailure hospitalizationCause hospitalizationCardiovascular hospitalizationResynchronization therapyNational Cardiovascular Data RegistryCRT-D implantationYear of implantHospital procedural complicationsHospital complicationsHospital outcomesMultivariable adjustmentPatient characteristicsProcedural complicationsDefibrillator recipientsHospitalizationData registryLower riskMedicare beneficiariesMedicare dataOutcomesRecipients
2021
Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion
Darden D, Duong T, Du C, Munir MB, Han FT, Reeves R, Saw J, Zeitler EP, Al-Khatib SM, Russo AM, Minges KE, Curtis JP, Freeman JV, Hsu JC. Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion. JAMA Cardiology 2021, 6: 1275-1284. PMID: 34379072, PMCID: PMC8358791, DOI: 10.1001/jamacardio.2021.3021.Peer-Reviewed Original ResearchConceptsHospital adverse eventsMajor adverse eventsAdverse eventsAtrial appendage occlusionMajor bleedingPericardial effusionAppendage occlusionAtrial fibrillationSex differencesCongestive heart failureCoronary artery diseaseAdjusted logistic regression analysisParoxysmal atrial fibrillationLogistic regression analysisMultivariable adjusted logistic regression analysesPrior strokeUncontrolled hypertensionHospital outcomesHospital stayMultivariable adjustmentProlonged hospitalBaseline characteristicsCohort studySelect patientsArtery diseaseTrends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation
Bourdillon PM, Parzynski CS, Minges KE, Curtis JP, Desai NR. Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation. Journal Of Cardiac Failure 2021, 28: 154-160. PMID: 34628015, DOI: 10.1016/j.cardfail.2021.09.010.Peer-Reviewed Original ResearchConceptsHospital adverse eventsHospital outcomesAdverse eventsHeart failureMyocardial infarctionRecent acute myocardial infarctionPlacement of ICDsPrimary prevention ICDsAdverse event ratesRecent myocardial infarctionAcute myocardial infarctionHigh mortality rateICD implantationRecent diagnosisMortality ratePatientsICDInfarctionHospitalOutcomesRapid reductionUse of devicesFailureSpecific reasonsCriteriaDefibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR. JACC Clinical Electrophysiology 2021, 7: 1145-1154. PMID: 33933411, DOI: 10.1016/j.jacep.2021.02.019.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseLowest successful energyHospital stayNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator insertionVentricular septal defectTetralogy of FallotHeart disease resultHospital complicationsHospital deathHospital outcomesMultivariable adjustmentEbstein's anomalyICD RegistryICD recipientsSeptal defectCommon ventricleHeart diseaseRetrospective analysisLower oddsGreat vesselsICD proceduresDisease resultsSuccessful energyICD generator
2020
Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis
Pun PH, Parzynski CS, Friedman DJ, Sanders G, Curtis JP, Al-Khatib SM. Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis. Clinical Journal Of The American Society Of Nephrology 2020, 15: 1622-1630. PMID: 32967922, PMCID: PMC7646229, DOI: 10.2215/cjn.07920520.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestSubcutaneous ICDTransvenous ICDICD implantsHospital outcomesICD recipientsICD RegistryCardiac arrestHigh riskNational Cardiovascular Data Registry ICD RegistryFirst-time ICD recipientsPropensity score-weighted analysisImplantable cardioverter defibrillator implantationSubcutaneous implantable cardioverter defibrillatorIn-Hospital OutcomesShort-term complicationsCardioverter-defibrillator implantationLong-term dialysisVascular access siteImplantable cardioverter defibrillatorCause deathHospital complicationsHospital stayDefibrillator implantationUS patients
2017
Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling.
Dharmarajan K, McNamara RL, Wang Y, Masoudi FA, Ross JS, Spatz EE, Desai NR, de Lemos JA, Fonarow GC, Heidenreich PA, Bhatt DL, Bernheim SM, Slattery LE, Khan YM, Curtis JP. Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling. Annals Of Internal Medicine 2017, 167: 555-564. PMID: 28973634, PMCID: PMC9359429, DOI: 10.7326/m16-2871.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesAcute myocardial infarctionOlder patientsYounger patientsMyocardial infarctionAge groupsHospital risk-standardized mortality ratesRetrospective cohort studyHospital mortality rankingsNational Quality ForumHospital mortalityMedian hospitalHospital outcomesCohort studyACTION RegistryAMI mortalityAmerican CollegeMedicare beneficiariesAMI hospitalizationPatientsMortality rateHospitalQuality ForumHospital ValueHospital profiling
2016
Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States
Friedman DJ, Parzynski CS, Varosy PD, Prutkin JM, Patton KK, Mithani A, Russo AM, Curtis JP, Al-Khatib SM. Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States. JAMA Cardiology 2016, 1: 900-911. PMID: 27603935, PMCID: PMC5112106, DOI: 10.1001/jamacardio.2016.2782.Peer-Reviewed Original ResearchConceptsSubcutaneous implantable cardioverter defibrillatorPropensity-matched analysisS-ICDHospital outcomesImplantable cardioverter defibrillatorICD implantsComplication rateICD RegistryDFT testingS-ICDsCardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryHospital complication ratesIn-Hospital OutcomesPrior cardiac arrestLow complication rateS-ICD implantationUse of ICDsSC-ICDICD implantationCardiac arrestMean ageRetrospective analysisMAIN OUTCOMEPatientsImpact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011)
Arora S, Panaich SS, Patel N, Patel NJ, Lahewala S, Thakkar B, Savani C, Jhamnani S, Singh V, Patel N, Patel S, Sonani R, Patel A, Tripathi B, Deshmukh A, Chothani A, Patel J, Bhatt P, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Mena CI, Schreiber T, Grines C, Cleman M, Forrest JK, Badheka AO. Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011). Catheterization And Cardiovascular Interventions 2016, 88: 605-616. PMID: 26914274, DOI: 10.1002/ccd.26452.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalCross-Sectional StudiesDatabases, FactualDrug CostsEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLimb SalvageLogistic ModelsLower ExtremityMaleMiddle AgedMultivariate AnalysisOdds RatioPeripheral Arterial DiseasePlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexPropensity ScoreRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsGlycoprotein IIb/IIIa inhibitorsPeripheral endovascular interventionsHospital mortalityHospitalization costsEndovascular interventionGPI useAmputation rateUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateIIb/IIIa inhibitorsNationwide Inpatient Sample databaseLower amputation ratesPaucity of dataHospital outcomesPostprocedural complicationsSecondary outcomesPropensity matchingStudy cohortHealthcare costsICD-9Multivariate analysisStudy outcomesSample databaseMortalityHierarchical multivariate
2015
Association of Physician Certification in Interventional Cardiology With In-Hospital Outcomes of Percutaneous Coronary Intervention
Fiorilli PN, Minges KE, Herrin J, Messenger JC, Ting HH, Nallamothu BK, Lipner RS, Hess BJ, Holmboe ES, Brennan JJ, Curtis JP. Association of Physician Certification in Interventional Cardiology With In-Hospital Outcomes of Percutaneous Coronary Intervention. Circulation 2015, 132: 1816-1824. PMID: 26384518, PMCID: PMC4641797, DOI: 10.1161/circulationaha.115.017523.Peer-Reviewed Original ResearchConceptsEmergency coronary artery bypassPercutaneous coronary interventionCoronary artery bypassArtery bypassVascular complicationsHospital mortalityEnd pointHospital outcomesCoronary interventionPCI proceduresIn-Hospital OutcomesPrimary end pointSecondary end pointsComposite end pointRisk of bleedingHierarchical multivariable modelInternal Medicine certificationAmerican BoardCathPCI RegistryPatient characteristicsPCI volumeUnadjusted outcomesAdverse outcomesPatient outcomesMultivariable model
2014
Transfer Rates From Nonprocedure Hospitals After Initial Admission and Outcomes Among Elderly Patients With Acute Myocardial Infarction
Barreto-Filho JA, Wang Y, Rathore SS, Spatz ES, Ross JS, Curtis JP, Nallamothu BK, Normand SL, Krumholz HM. Transfer Rates From Nonprocedure Hospitals After Initial Admission and Outcomes Among Elderly Patients With Acute Myocardial Infarction. JAMA Internal Medicine 2014, 174: 213-222. PMID: 24296747, DOI: 10.1001/jamainternmed.2013.11944.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCoronary artery bypass graft surgeryArtery bypass graft surgeryRisk-standardized mortality ratesBypass graft surgeryPercutaneous coronary interventionLength of stayMyocardial infarctionElderly patientsGraft surgeryRevascularization ratesCoronary interventionMortality rateLower risk-standardized mortality ratesRate of catheterizationHospital transfer ratesInvasive cardiac proceduresTransfer of patientsRisk-standardized mortalityHospital outcomesInitial admissionMedian lengthService patientsCardiac proceduresHospital differences
2011
Non–Evidence-Based ICD Implantations in the United States
Al-Khatib SM, Hellkamp A, Curtis J, Mark D, Peterson E, Sanders GD, Heidenreich PA, Hernandez AF, Curtis LH, Hammill S. Non–Evidence-Based ICD Implantations in the United States. JAMA 2011, 305: 43-49. PMID: 21205965, PMCID: PMC3432303, DOI: 10.1001/jama.2010.1915.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiologyCohort StudiesCoronary Artery BypassDeath, Sudden, CardiacDefibrillators, ImplantableEvidence-Based MedicineFemaleGuideline AdherenceHeart FailureHospital MortalityHumansMaleMiddle AgedMyocardial InfarctionPatient SelectionPractice Patterns, Physicians'Primary PreventionRegistriesRetrospective StudiesTreatment OutcomeUnited StatesConceptsICD implantsHospital outcomesNational Cardiovascular Data Registry ICD RegistryCoronary artery bypass graft surgerySevere heart failure symptomsArtery bypass graft surgeryBypass graft surgeryHeart failure symptomsRetrospective cohort studyYear of procedureEvidence-based criteriaGraft surgeryHospital deathCohort studyICD implantationHeart failurePostprocedure complicationsPrimary preventionMyocardial infarctionRecent diagnosisFailure symptomsPhysician specialtyPractice guidelinesMAIN OUTCOMEHigh risk
2009
Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation
Aggarwal A, Wang Y, Rumsfeld JS, Curtis JP, Heidenreich PA, Registry C. Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation. Heart Rhythm 2009, 6: 1565-1571. PMID: 19879533, DOI: 10.1016/j.hrthm.2009.08.006.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationESRD patientsCardioverter-defibrillator implantationICD implantationHospital complicationsTotal complicationsHospital stayPrimary preventionEnd-stage renal disease patientsEnd-stage renal diseaseComorbid medical conditionsRenal disease patientsHigh rateERSD patientsHospital mortalityHospital outcomesClinical characteristicsAngiotensin inhibitorsClinical profileICD RegistryMajor complicationsPrimary outcomeRenal diseaseMultivariable analysisDevice implantation