2022
Patient-Level Analysis of Watchman Left Atrial Appendage Occlusion in Practice Versus Clinical Trials
Friedman DJ, Du C, Wang Y, Agarwal V, Varosy PD, Masoudi FA, Holmes DR, Reddy VY, Price MJ, Curtis JP, Freeman JV. Patient-Level Analysis of Watchman Left Atrial Appendage Occlusion in Practice Versus Clinical Trials. JACC Cardiovascular Interventions 2022, 15: 950-961. PMID: 35512918, PMCID: PMC9370831, DOI: 10.1016/j.jcin.2022.02.029.Peer-Reviewed Original ResearchConceptsRegistry patientsHemorrhagic stroke riskIschemic strokeWarfarin patientsTrial patientsStroke riskLAAO patientsClinical practiceMore pericardial effusionsPeriprocedural ischemic strokePropensity-matched analysisAtrial appendage occlusionCox proportional hazardsPatient-level dataFine-Gray modelMore comorbiditiesPROTECT AFNoncardiovascular deathPericardial effusionHemorrhagic strokeAppendage occlusionDevice implantationTrial criteriaClinical trialsSimilar risk
2021
Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry)
Daimee UA, Aslam F, Parzynski CS, Desai NR, Curtis JP. Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry). The American Journal Of Cardiology 2021, 155: 64-71. PMID: 34315569, DOI: 10.1016/j.amjcard.2021.06.020.Peer-Reviewed Original ResearchConceptsPrimary prevention ICD implantationRisk of mortalityICD implantationHeart failureICD RegistryMortality riskNational Cardiovascular Data Registry ICD RegistryPivotal randomized clinical trialsHospital adverse eventsSevere heart failureRecent myocardial infarctionCause hospital readmissionRandomized clinical trialsSimilar mortality riskLongitudinal outcomesImplantable cardioverter defibrillatorGreater mortality riskCause hospitalizationCause mortalityCoronary revascularizationAdverse eventsHospital readmissionICD recipientsDevice implantationPrimary prevention
2019
Institutional Variation in Quality of Cardiovascular Implantable Electronic Device Implantation: A Cohort Study.
Ranasinghe I, Labrosciano C, Horton D, Ganesan A, Curtis JP, Krumholz HM, McGavigan A, Hossain S, Air T, Hariharaputhiran S. Institutional Variation in Quality of Cardiovascular Implantable Electronic Device Implantation: A Cohort Study. Annals Of Internal Medicine 2019, 171: 309-317. PMID: 31357210, DOI: 10.7326/m18-2810.Peer-Reviewed Original ResearchConceptsCardiovascular implantable electronic devicesComplication rateCohort studyCIED complicationsCardiovascular implantable electronic device (CIED) implantationMajor device-related complicationsDays of dischargeDevice-related complicationsProcedure-related complicationsImplantable electronic devicesPPM implantationMajor complicationsICD placementDevice implantationElective proceduresComplicationsHospitalCare qualityStudy periodPatientsAdministrative dataInstitutional variationNational averageImplantation
2017
Use of Cardiac Resynchronization Therapy Among Eligible Patients Receiving an Implantable Cardioverter Defibrillator: Insights From the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Marzec LN, Peterson PN, Bao H, Curtis JP, Masoudi FA, Varosy PD, Bradley SM. Use of Cardiac Resynchronization Therapy Among Eligible Patients Receiving an Implantable Cardioverter Defibrillator: Insights From the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Cardiology 2017, 2: 561-565. PMID: 28122073, PMCID: PMC5814986, DOI: 10.1001/jamacardio.2016.5388.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationBlack or African AmericanBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesCerebrovascular DisordersCohort StudiesComorbidityDefibrillators, ImplantableDiabetes MellitusEthnicityFemaleHealth Facility SizeHeart FailureHospitalsHospitals, TeachingHumansHypertensionInsurance, HealthLung DiseasesMaleMedicaidMedicareMiddle AgedMortalityMyocardial IschemiaPractice Patterns, Physicians'RegistriesRegression AnalysisRetrospective StudiesUnited StatesWhite PeopleConceptsUse of CRTCardiac resynchronization therapyCRT-D useImplantable cardioverter defibrillatorGuideline-eligible patientsDevice implantationEligible patientsResynchronization therapyCardioverter defibrillatorNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryNational Cardiovascular Data Registry ICD RegistryHeart failure-related eventsImplantable Cardioverter-Defibrillator RegistryCRT-D groupMulticenter retrospective cohortRisk-standardized ratesHospital-level variationCRT-D devicesHierarchical multivariable modelNonprivate insuranceRetrospective cohortSelect patientsICD RegistryGuideline recommendationsICD placementAddition of Blood Pressure and Weight Transmissions to Standard Remote Monitoring of Implantable Defibrillators and its Association with Mortality and Rehospitalization
Al-Chekakie MO, Bao H, Jones PW, Stein KM, Marzec L, Varosy PD, Masoudi FA, Curtis JP, Akar JG. Addition of Blood Pressure and Weight Transmissions to Standard Remote Monitoring of Implantable Defibrillators and its Association with Mortality and Rehospitalization. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003087. PMID: 28506978, DOI: 10.1161/circoutcomes.116.003087.Peer-Reviewed Original ResearchConceptsBlood pressure dataImplantable defibrillatorsRemote patient monitoringTransmission of weightHeart failure hospitalizationImpaired ejection fractionCardiac resynchronization therapyCox regression modelRisk of mortalityLogistic regression modelsRoutine weightCause hospitalizationFailure hospitalizationBlood pressureCardiovascular hospitalizationEjection fractionResynchronization therapyRegression modelsDevice implantationService patientsHospital characteristicsIndependent associationImproved outcomesLandmark analysisSimilar risk
2009
Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation
Aggarwal A, Wang Y, Rumsfeld JS, Curtis JP, Heidenreich PA, Registry C. Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation. Heart Rhythm 2009, 6: 1565-1571. PMID: 19879533, DOI: 10.1016/j.hrthm.2009.08.006.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationESRD patientsCardioverter-defibrillator implantationICD implantationHospital complicationsTotal complicationsHospital stayPrimary preventionEnd-stage renal disease patientsEnd-stage renal diseaseComorbid medical conditionsRenal disease patientsHigh rateERSD patientsHospital mortalityHospital outcomesClinical characteristicsAngiotensin inhibitorsClinical profileICD RegistryMajor complicationsPrimary outcomeRenal diseaseMultivariable analysisDevice implantation