2022
Longitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients
Friedman DJ, Qin L, Parzynski C, Heist EK, Russo AM, Ranasinghe I, Zeitler EP, Minges KE, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM. Longitudinal Outcomes of Subcutaneous or Transvenous Implantable Cardioverter-Defibrillators in Older Patients. Journal Of The American College Of Cardiology 2022, 79: 1050-1059. PMID: 35300816, DOI: 10.1016/j.jacc.2021.12.033.Peer-Reviewed Original ResearchConceptsOlder patientsCause readmissionS-ICDNational Cardiovascular Data Registry ICD RegistryDevice removalTransvenous implantable cardioverter defibrillatorTV-ICD patientsRisk of deathS-ICD patientsService Medicare beneficiariesAnderson-Gill modelsImplantable cardioverter defibrillatorRepresentative national cohortCompeting-risks modelTV-ICDCardiovascular readmissionCause mortalityICD implantationYounger patientsICD RegistryNonfatal outcomesTransvenous ICDAtrial fibrillationNational cohortCardioverter defibrillator
2019
Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipients
Bilchick KC, Wang Y, Curtis JP, Cheng A, Dharmarajan K, Shadman R, Dardas TF, Anand I, Lund LH, Dahlström U, Sartipy U, Maggioni A, O'Connor C, Levy WC. Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipients. American Heart Journal 2019, 222: 93-104. PMID: 32032927, PMCID: PMC7814502, DOI: 10.1016/j.ahj.2019.12.017.Peer-Reviewed Original ResearchConceptsCRT-D patientsImplantable cardioverter defibrillatorSurvival benefitCRT-DsCardiac resynchronization therapy defibrillator recipientsCardiac resynchronization therapy candidatesSeattle Heart Failure ModelSeattle Proportional Risk ModelCox proportional hazards regressionNational Cardiovascular Data RegistryHeart Failure TrialHeart failure patientsProportional hazards regressionHeart failure modelProportional risk modelFailure patientsCRT candidatesHeart failureCRT pacemakerFailure TrialArrhythmic deathHazards regressionDefibrillator recipientsCRT deviceCardioverter defibrillatorIMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY IN THE UNITED STATES: INSIGHTS FROM THE NCDR ICD REGISTRY, AN NCDR® RESEARCH TO PRACTICE (R2P) PROJECT
Kutyifa V, Bao H, Cha Y, Hsu J, Varosy P, Masoudi F, Curtis J, Peterson P. IMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY IN THE UNITED STATES: INSIGHTS FROM THE NCDR ICD REGISTRY, AN NCDR® RESEARCH TO PRACTICE (R2P) PROJECT. Journal Of The American College Of Cardiology 2019, 73: 311. DOI: 10.1016/s0735-1097(19)30919-2.Peer-Reviewed Original Research
2018
Association of the US Department of Justice Investigation of Implantable Cardioverter-Defibrillators and Devices Not Meeting the Medicare National Coverage Determination, 2007-2015
Desai NR, Bourdillon PM, Parzynski CS, Brindis RG, Spatz ES, Masters C, Minges KE, Peterson P, Masoudi FA, Oetgen WJ, Buxton A, Zipes DP, Curtis JP. Association of the US Department of Justice Investigation of Implantable Cardioverter-Defibrillators and Devices Not Meeting the Medicare National Coverage Determination, 2007-2015. JAMA 2018, 320: 63-71. PMID: 29971398, PMCID: PMC6583049, DOI: 10.1001/jama.2018.8151.Peer-Reviewed Original ResearchConceptsPrimary prevention ICDsNon-Medicare beneficiariesAbsolute decreaseNational Cardiovascular Data Registry ICD RegistrySerial cross-sectional analysisStudy periodImplantable cardioverter defibrillatorRelative decreaseCross-sectional analysisProportion of devicesInitial ICDICD RegistryPrimary preventionCardioverter defibrillatorMAIN OUTCOMEMedicare beneficiariesUS hospitalsHospital groupHospitalICDMore rapid decreasesModest decreaseDepartmentMedicareUS DepartmentVentricular Fibrillation Conversion Testing After Implantation of a Subcutaneous Implantable Cardioverter Defibrillator
Friedman DJ, Parzynski CS, Heist EK, Russo AM, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM. Ventricular Fibrillation Conversion Testing After Implantation of a Subcutaneous Implantable Cardioverter Defibrillator. Circulation 2018, 137: 2463-2477. PMID: 29463509, PMCID: PMC5988932, DOI: 10.1161/circulationaha.117.032167.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorS-ICD implantationLogistic regression analysisInhospital complicationsPatient characteristicsCT testingS-ICDsCardioverter defibrillatorConversion testingPrior implantable cardioverter defibrillatorHigher body mass indexMultivariable logistic regression analysisLarger body surface areaSubcutaneous implantable cardioverter defibrillatorTransvenous implantable cardioverter defibrillatorInhospital adverse eventsLow ejection fractionAvailable patient characteristicsBody mass indexBody surface areaFirst-time recipientsMaximum device outputRegression analysisPredictors of useInsufficient safety margin
2017
Use of Cardiac Resynchronization Therapy Among Eligible Patients Receiving an Implantable Cardioverter Defibrillator: Insights From the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Marzec LN, Peterson PN, Bao H, Curtis JP, Masoudi FA, Varosy PD, Bradley SM. Use of Cardiac Resynchronization Therapy Among Eligible Patients Receiving an Implantable Cardioverter Defibrillator: Insights From the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Cardiology 2017, 2: 561-565. PMID: 28122073, PMCID: PMC5814986, DOI: 10.1001/jamacardio.2016.5388.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationBlack or African AmericanBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesCerebrovascular DisordersCohort StudiesComorbidityDefibrillators, ImplantableDiabetes MellitusEthnicityFemaleHealth Facility SizeHeart FailureHospitalsHospitals, TeachingHumansHypertensionInsurance, HealthLung DiseasesMaleMedicaidMedicareMiddle AgedMortalityMyocardial IschemiaPractice Patterns, Physicians'RegistriesRegression AnalysisRetrospective StudiesUnited StatesWhite PeopleConceptsUse of CRTCardiac resynchronization therapyCRT-D useImplantable cardioverter defibrillatorGuideline-eligible patientsDevice implantationEligible patientsResynchronization therapyCardioverter defibrillatorNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryNational Cardiovascular Data Registry ICD RegistryHeart failure-related eventsImplantable Cardioverter-Defibrillator RegistryCRT-D groupMulticenter retrospective cohortRisk-standardized ratesHospital-level variationCRT-D devicesHierarchical multivariable modelNonprivate insuranceRetrospective cohortSelect patientsICD RegistryGuideline recommendationsICD placementSeattle Heart Failure and Proportional Risk Models Predict Benefit From Implantable Cardioverter-Defibrillators
Bilchick KC, Wang Y, Cheng A, Curtis JP, Dharmarajan K, Stukenborg GJ, Shadman R, Anand I, Lund LH, Dahlström U, Sartipy U, Maggioni A, Swedberg K, O’Conner C, Levy WC. Seattle Heart Failure and Proportional Risk Models Predict Benefit From Implantable Cardioverter-Defibrillators. Journal Of The American College Of Cardiology 2017, 69: 2606-2618. PMID: 28545633, PMCID: PMC5502749, DOI: 10.1016/j.jacc.2017.03.568.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelSeattle Proportional Risk ModelNational Cardiovascular Data RegistryPrimary prevention ICDsHeart failureSudden deathCause mortalitySurvival benefitMultivariable Cox proportional hazards regressionCox proportional hazards regressionProportional riskProportional hazards regressionRecent clinical trialsHeart failure modelProportional risk modelControl patientsOverall survivalVentricular arrhythmiasHazards regressionICD benefitClinical trialsCardioverter defibrillatorLarge cohortHigh riskData registry
2016
Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States
Friedman DJ, Parzynski CS, Varosy PD, Prutkin JM, Patton KK, Mithani A, Russo AM, Curtis JP, Al-Khatib SM. Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States. JAMA Cardiology 2016, 1: 900-911. PMID: 27603935, PMCID: PMC5112106, DOI: 10.1001/jamacardio.2016.2782.Peer-Reviewed Original ResearchConceptsSubcutaneous implantable cardioverter defibrillatorPropensity-matched analysisS-ICDHospital outcomesImplantable cardioverter defibrillatorICD implantsComplication rateICD RegistryDFT testingS-ICDsCardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryHospital complication ratesIn-Hospital OutcomesPrior cardiac arrestLow complication rateS-ICD implantationUse of ICDsSC-ICDICD implantationCardiac arrestMean ageRetrospective analysisMAIN OUTCOMEPatientsAssociation Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy
Friedman DJ, Bao H, Spatz ES, Curtis JP, Daubert JP, Al-Khatib SM. Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy. Circulation 2016, 134: 1617-1628. PMID: 27760795, PMCID: PMC5418126, DOI: 10.1161/circulationaha.116.022913.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationFailure hospitalizationPR intervalImplantable cardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy candidatesIncident heart failure hospitalizationReal-world comparative effectivenessCRT-eligible patientsReceipt of CRTChronic kidney diseaseCardiac resynchronization therapyCRT-D patientsCoronary artery diseaseProlonged PR intervalComparative effectiveness analysisMore comorbiditiesArtery diseaseDiabetes mellitusICD recipientsICD RegistryResynchronization therapyAtrial arrhythmiasKidney diseaseCardioverter defibrillator
2015
Use of Remote Monitoring Is Associated With Lower Risk of Adverse Outcomes Among Patients With Implanted Cardiac Defibrillators
Akar JG, Bao H, Jones PW, Wang Y, Varosy PD, Masoudi FA, Stein KM, Saxon LA, Normand SL, Curtis JP. Use of Remote Monitoring Is Associated With Lower Risk of Adverse Outcomes Among Patients With Implanted Cardiac Defibrillators. Circulation Arrhythmia And Electrophysiology 2015, 8: 1173-1180. PMID: 26092577, DOI: 10.1161/circep.114.003030.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorInitial implantable cardioverter defibrillatorCause mortalityLower riskAdverse outcomesNational Cardiovascular Data Registry ICD RegistryRemote patient monitoringSocial Security Death Master FileCause rehospitalization rateRisk of rehospitalizationImplanted cardiac defibrillatorsDeath Master FileCardiomyopathy pathogenesisCause rehospitalizationICD RegistryRehospitalization ratesMultivariable analysisStudy cohortVital statusService patientsCardioverter defibrillatorCox modelMedicare populationMedicare feePatientsCardiac Resynchronization Therapy in Women Versus Men
Zusterzeel R, Spatz ES, Curtis JP, Sanders WE, Selzman KA, Piña IL, Bao H, Ponirakis A, Varosy PD, Masoudi FA, Caños DA, Strauss DG. Cardiac Resynchronization Therapy in Women Versus Men. Circulation Cardiovascular Quality And Outcomes 2015, 8: s4-s11. PMID: 25714821, DOI: 10.1161/circoutcomes.114.001548.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesDefibrillators, ImplantableElectric CountershockFemaleHealth Status DisparitiesHeart Conduction SystemHeart FailureHumansKaplan-Meier EstimateMalePropensity ScoreProportional Hazards ModelsRegistriesRisk FactorsSex FactorsStroke VolumeTreatment OutcomeUnited StatesVentricular Function, LeftConceptsLeft bundle branch blockQRS durationImplantable cardioverter defibrillatorPatient sexDeath riskCardioverter defibrillatorBetter survivalMortality differencesNew York Heart Association class IIILeft ventricular ejection fractionWomen Versus MenCardiac resynchronization therapyVentricular ejection fractionRelative death riskBenefit of CRTLonger QRS durationShorter QRS durationBundle branch blockLower mortality riskEjection fractionHeart failureResynchronization therapyCardiac resynchronizationBranch blockMortality risk
2014
Primary Prevention Implantable Cardioverter-Defibrillators and Survival in Older Women
Zeitler EP, Hellkamp AS, Fonarow GC, Hammill SC, Curtis LH, Hernandez AF, Al-Khalidi HR, Curtis JP, Heidenreich PA, Anstrom KJ, Peterson ED, Mark DB, Hammill BG, Sanders GD, Al-Khatib SM. Primary Prevention Implantable Cardioverter-Defibrillators and Survival in Older Women. JACC Heart Failure 2014, 3: 159-167. PMID: 25543969, PMCID: PMC4461749, DOI: 10.1016/j.jchf.2014.09.006.Peer-Reviewed Original ResearchConceptsPrimary prevention implantable cardioverter defibrillatorsImplantable cardioverter defibrillatorHeart failureCardioverter defibrillatorOlder womenNational Cardiovascular Data Registry ICD RegistryLeft ventricular dysfunctionSignificant survival benefitSurvival of womenYears of ageMedicare claims databaseEligible patientsCause mortalityPrimary endpointVentricular dysfunctionSurvival benefitICD RegistryClaims databaseHeart failure databaseLonger survivalClinical trialsPropensity score methodsPatientsWomenSurvivalIn-Hospital Complications Associated With Reoperations of Implantable Cardioverter Defibrillators
Steckman DA, Varosy PD, Parzynski CS, Masoudi FA, Curtis JP, Sauer WH, Nguyen DT. In-Hospital Complications Associated With Reoperations of Implantable Cardioverter Defibrillators. The American Journal Of Cardiology 2014, 114: 419-426. PMID: 24927972, DOI: 10.1016/j.amjcard.2014.05.010.Peer-Reviewed Original ResearchConceptsHospital complicationsComplication rateRepeat proceduresLead extractionICD proceduresMultivariable adjusted odds ratiosNational Cardiovascular Data RegistryInitial implantImplantable cardioverter-defibrillator (ICD) proceduresHierarchical multivariable logistic regressionHospital adverse eventsAdjusted odds ratioHigh complication rateMultivariable logistic regressionLarge national cohortImplantable cardioverter defibrillatorHospital deathAdverse eventsICD implantationPatient characteristicsNational cohortOdds ratioProcedural outcomesCardioverter defibrillatorHigh risk
2013
Temporal Trends in Quality of Care Among Recipients of Implantable Cardioverter-Defibrillators
Dodson JA, Lampert R, Wang Y, Hammill SC, Varosy P, Curtis JP. Temporal Trends in Quality of Care Among Recipients of Implantable Cardioverter-Defibrillators. Circulation 2013, 129: 580-586. PMID: 24192798, PMCID: PMC3946506, DOI: 10.1161/circulationaha.113.003747.Peer-Reviewed Original ResearchConceptsOptimal medical therapyCardiac resynchronization therapyAdverse eventsEligible patientsQuality of careICD RegistryPotential confoundersNew York Heart Association class III/IVClass III/IVAngiotensin-converting enzyme inhibitorAngiotensin receptor blockersVentricular ejection fractionNew ICD implantsImplantable cardioverter defibrillatorHierarchical logistic regressionCRT eligibilityReceptor blockersEjection fractionMedical therapyResynchronization therapyICD implantsObservational studyCardioverter defibrillatorΒ-blockersPatientsCardiovascular Care Facts A Report From the National Cardiovascular Data Registry: 2011
Masoudi FA, Ponirakis A, Yeh RW, Maddox TM, Beachy J, Casale PN, Curtis JP, De Lemos J, Fonarow G, Heidenreich P, Koutras C, Kremers M, Messenger J, Moussa I, Oetgen WJ, Roe MT, Rosenfield K, Shields TP, Spertus JA, Wei J, White C, Young CH, Rumsfeld JS. Cardiovascular Care Facts A Report From the National Cardiovascular Data Registry: 2011. Journal Of The American College Of Cardiology 2013, 62: 1931-1947. PMID: 24036027, DOI: 10.1016/j.jacc.2013.05.099.Peer-Reviewed Original ResearchConceptsQuality of careACTION Registry-GWTGCardiovascular diseasePatient outcomesAcute coronary syndromePercutaneous coronary interventionImportant patient outcomesImplantable cardioverter defibrillatorNational registry programMeasure of ProcessesNCDR modelsPINNACLE RegistryCoronary syndromeCarotid revascularizationCathPCI RegistryClinical characteristicsCoronary interventionCare registriesRegistry programLeading causeCardiovascular careCardioverter defibrillatorPatientsRegistryHospitalUse of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators
Akar JG, Bao H, Jones P, Wang Y, Chaudhry SI, Varosy P, Masoudi FA, Stein K, Saxon LA, Curtis JP. Use of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators. Circulation 2013, 128: 2372-2383. PMID: 24043302, DOI: 10.1161/circulationaha.113.002481.Peer-Reviewed Original ResearchConceptsMedian odds ratioOdds ratioNational Cardiovascular Data Registry ICD RegistryRemote patient monitoringMultivariable logistic regressionHealth-related factorsImplanted cardioverter defibrillatorEligible patientsICD RegistryLack of enrollmentCurrent guidelinesCardioverter defibrillatorPatientsLogistic regressionLocal practice environmentMajor causeHealth insuranceSubsequent activationEnrollmentPractice environmentPatient monitoringPhysiciansActivationRPM systemSuccessful use
2010
Regional Variation in the Use of Implantable Cardioverter-Defibrillators for Primary Prevention
Matlock DD, Peterson PN, Heidenreich PA, Lucas FL, Malenka DJ, Wang Y, Curtis JP, Kutner JS, Fisher ES, Masoudi FA. Regional Variation in the Use of Implantable Cardioverter-Defibrillators for Primary Prevention. Circulation Cardiovascular Quality And Outcomes 2010, 4: 114-121. PMID: 21139094, DOI: 10.1161/circoutcomes.110.958264.Peer-Reviewed Original ResearchConceptsPrimary prevention ICDsProportion of patientsTrial inclusion criteriaInclusion criteriaPrimary preventionTrial criteriaPhysician supplyNational Cardiovascular Data RegistryImplantable cardioverter defibrillatorHospital referral regionsRace-adjusted ratesCross-sectional analysisICD implantationICD placementCardioverter defibrillatorReferral regionsData registryPotential overusePatientsICDDeath variesRate ratioService populationGeographic variationRegional variationIMPACT OF THE MEDTRONIC FIDELIS LEAD RECALL ON UTILIZATION OF IMPLANTABLE CARDIOVERTER DEFIBRILLATORS: DATA FROM THE NCDR ICD REGISTRY
Bhatt P, Curtis J, Wang Y, Lampert R. IMPACT OF THE MEDTRONIC FIDELIS LEAD RECALL ON UTILIZATION OF IMPLANTABLE CARDIOVERTER DEFIBRILLATORS: DATA FROM THE NCDR ICD REGISTRY. Journal Of The American College Of Cardiology 2010, 55: a14.e132. DOI: 10.1016/s0735-1097(10)60133-7.Peer-Reviewed Original Research
2009
Use of implantable cardioverter defibrillators for primary prevention in the community: Do women and men equally meet trial enrollment criteria?
Daugherty SL, Peterson PN, Wang Y, Curtis JP, Heidenreich PA, Lindenfeld J, Vidaillet HJ, Masoudi FA, behalf of the NCDR O. Use of implantable cardioverter defibrillators for primary prevention in the community: Do women and men equally meet trial enrollment criteria? American Heart Journal 2009, 158: 224-229. PMID: 19619698, DOI: 10.1016/j.ahj.2009.05.018.Peer-Reviewed Original ResearchConceptsTrial enrollment criteriaPrimary prevention ICD implantationEnrollment criteriaICD implantationMADIT-IIMultivariable analysisPrimary preventionTrial criteriaNational Cardiovascular Data Registry ICD RegistryPrimary prevention ICD placementImplantable cardioverter defibrillator implantationSCD-HeFT trialsCardioverter-defibrillator implantationSudden cardiac deathImplantable cardioverter defibrillatorDefibrillator implantationSCD-HeFTYounger patientsCardiac deathICD RegistryICD placementNational cohortCardioverter defibrillatorOlder womenPatientsAssociation of Physician Certification and Outcomes Among Patients Receiving an Implantable Cardioverter-Defibrillator
Curtis JP, Luebbert JJ, Wang Y, Rathore SS, Chen J, Heidenreich PA, Hammill SC, Lampert RI, Krumholz HM. Association of Physician Certification and Outcomes Among Patients Receiving an Implantable Cardioverter-Defibrillator. JAMA 2009, 301: 1661-1670. PMID: 19383957, PMCID: PMC2805129, DOI: 10.1001/jama.2009.547.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac ElectrophysiologyCertificationClinical CompetenceDefibrillators, ImplantableFemaleHumansIntraoperative ComplicationsLogistic ModelsMaleMedicineMiddle AgedOutcome and Process Assessment, Health CarePhysiciansPostoperative ComplicationsProsthesis ImplantationRegistriesRetrospective StudiesSpecializationTreatment OutcomeUnited StatesConceptsCRT-D devicesThoracic surgeonsICD implantationPhysician certificationImplantable cardioverter-defibrillator (ICD) proceduresRetrospective cohort studyCardiac resynchronization therapyPatients meeting criteriaRisk of complicationsProcedural complication rateImplantable cardioverter defibrillatorHierarchical logistic regression modelsLogistic regression modelsCohort studyComplication rateICD RegistryResynchronization therapyProcedural complicationsIndependent associationPhysician specialtyCardioverter defibrillatorHigh riskPatientsMeeting criteriaNonelectrophysiologists