2016
Renal dysfunction and chronic mechanical circulatory support
Brisco MA, Testani JM, Cook JL. Renal dysfunction and chronic mechanical circulatory support. Current Opinion In Cardiology 2016, 31: 277-286. PMID: 27022890, PMCID: PMC6176489, DOI: 10.1097/hco.0000000000000278.Peer-Reviewed Original ResearchConceptsMechanical circulatory supportRenal dysfunctionRenal functionCirculatory supportChronic mechanical circulatory supportPostoperative acute kidney injuryIrreversible renal dysfunctionAcute kidney injuryRight ventricular dysfunctionAdvanced heart failureCardiogenic shockKidney injuryNeurohormonal activationVentricular dysfunctionMost patientsHeart failureKidney functionSubsequent recurrenceVolume overloadVenous congestionEarly improvementDysfunctionDevice-related effectsReversible formDiagnostic tests
2013
Blood Urea Nitrogen/Creatinine Ratio Identifies a High-Risk but Potentially Reversible Form of Renal Dysfunction in Patients With Decompensated Heart Failure
Brisco MA, Coca SG, Chen J, Owens AT, McCauley BD, Kimmel SE, Testani JM. Blood Urea Nitrogen/Creatinine Ratio Identifies a High-Risk but Potentially Reversible Form of Renal Dysfunction in Patients With Decompensated Heart Failure. Circulation Heart Failure 2013, 6: 233-239. PMID: 23325460, PMCID: PMC4067251, DOI: 10.1161/circheartfailure.112.968230.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiomarkersBlood Urea NitrogenCardio-Renal SyndromeChi-Square DistributionCreatinineFemaleGlomerular Filtration RateHeart FailureHumansKaplan-Meier EstimateKidneyLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient AdmissionPrognosisProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsUp-RegulationConceptsReversible renal dysfunctionBUN/CrBlood urea nitrogen/creatinine ratioUrea nitrogen/creatinine ratioHeart failureRenal functionRenal dysfunctionCreatinine ratioElevated BUN/CrPatients meeting eligibility criteriaDecompensated heart failure patientsDecompensated heart failureHigh-risk patientsHeart failure patientsGlomerular filtration rateRisk of deathMeeting eligibility criteriaConsecutive hospitalizationsBaseline characteristicsFailure patientsDischarge diagnosisFiltration rateEligibility criteriaPatientsReversible form