2019
Patterns of amiodarone use and outcomes in clinical practice for atrial fibrillation
Pokorney SD, Holmes DN, Shrader P, Thomas L, Fonarow GC, Mahaffey KW, Gersh BJ, Kowey PR, Naccarelli GV, Freeman JV, Singer DE, Washam JB, Peterson ED, Piccini JP, Reiffel JA. Patterns of amiodarone use and outcomes in clinical practice for atrial fibrillation. American Heart Journal 2019, 220: 145-154. PMID: 31812756, DOI: 10.1016/j.ahj.2019.09.017.Peer-Reviewed Original ResearchConceptsUse of amiodaroneAmiodarone useAntiarrhythmic drugsAtrial fibrillationAF patientsDifferent antiarrhythmic drugsGuideline-based indicationsPropensity-matched cohortEffective antiarrhythmic drugProportional hazard modelingORBIT-AF registryLogistic regression modelsHierarchical logistic regressionCause mortalityAF RegistryCardiovascular hospitalizationAmiodaroneHigh incidencePatientsClinical practiceHazard modelingLogistic regressionAdverse effectsRandom interceptFibrillation
2011
Physician Procedure Volume and Complications of Cardioverter-Defibrillator Implantation
Freeman JV, Wang Y, Curtis JP, Heidenreich PA, Hlatky MA. Physician Procedure Volume and Complications of Cardioverter-Defibrillator Implantation. Circulation 2011, 125: 57-64. PMID: 22095828, DOI: 10.1161/circulationaha.111.046995.Peer-Reviewed Original ResearchConceptsPhysician procedure volumeProcedure volumeHospital mortalityICD implantationHospital characteristicsPhysician specialtyNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator placementInitial ICD implantationRate of complicationsCardioverter-defibrillator implantationHospital procedure volumeClustering of patientsAnnual procedure volumeOutcomes of proceduresVolume of proceduresHierarchical logistic regressionHospital complicationsComplication rateHospital volumePatient characteristicsProcedural complicationsHighest quartileInverse relationshipComplications