Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT‐AF Registry
Jackson LR, Kim SH, Piccini JP, Gersh BJ, Naccarelli GV, Reiffel JA, Freeman J, Thomas L, Chang P, Fonarow GC, Go AS, Mahaffey KW, Peterson ED, Kowey PR. Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT‐AF Registry. Clinical Cardiology 2015, 39: 119-125. PMID: 26720750, PMCID: PMC4784163, DOI: 10.1002/clc.22504.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationChi-Square DistributionComorbidityDisease ProgressionFemaleHumansLogistic ModelsMaleOdds RatioProportional Hazards ModelsProspective StudiesQuality of LifeRegistriesRisk AssessmentRisk FactorsSeverity of Illness IndexSick Sinus SyndromeTime FactorsTreatment OutcomeUnited StatesConceptsSinus node dysfunctionPermanent atrial fibrillationHigh symptom burdenAtrial fibrillationRisk-adjusted outcomesSymptom burdenTreatment patternsComorbid medical illnessesOutcomes of patientsAdverse cardiovascular outcomesParoxysmal atrial fibrillationPersistent atrial fibrillationORBIT-AF registryAF management strategyLogistic regression analysisCardiovascular outcomesComorbid illnessesAtrial tachyarrhythmiasMedical illnessHigh riskSevere symptomsPatientsDysfunctionOutcomesRegression analysis