2021
Implantable Cardioverter Defibrillator Lead Survival in Athletic Patients
Link MS, Sullivan RM, Olshansky B, Cannom D, Berul CI, Hauser RG, Heidbuchel H, Jordaens L, Krahn AD, Morgan J, Patton KK, Saarel EV, Wilkoff BL, Li F, Dziura J, Brandt C, Barth C, Lampert R. Implantable Cardioverter Defibrillator Lead Survival in Athletic Patients. Circulation Arrhythmia And Electrophysiology 2021, 14: e009344. PMID: 33724879, DOI: 10.1161/circep.120.009344.Peer-Reviewed Original Research
2020
Association of prescription opioids and incident cardiovascular risk factors among post-9/11 Veterans
Chui PW, Gordon KS, Dziura J, Burg MM, Brandt CA, Sico JJ, Leapman MS, Cavanagh CE, Rosman L, Haskell S, Becker WC, Bastian LA. Association of prescription opioids and incident cardiovascular risk factors among post-9/11 Veterans. Preventive Medicine 2020, 134: 106036. PMID: 32097753, DOI: 10.1016/j.ypmed.2020.106036.Peer-Reviewed Original ResearchConceptsCVD risk factorsLong-term opioid therapyCurrent smoking statusRisk factorsOpioid useOpioid therapySmoking statusCardiovascular diseaseHigh riskLong-term exposureIncident cardiovascular risk factorsModifiable CVD risk factorsPrevalent CVD risk factorsFirst primary care visitCardiovascular risk factorsPrimary care visitsBaseline periodElectronic health record dataMain outcome measuresHealth record dataOpioid prescriptionsCare visitsPrescription opioidsMain exposureOutcome measures
2019
Posttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults
Rosman L, Lampert R, Ramsey CM, Dziura J, Chui PW, Brandt C, Haskell S, Burg MM. Posttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults. Journal Of The American Heart Association 2019, 8: e013741. PMID: 31564191, PMCID: PMC6806049, DOI: 10.1161/jaha.119.013741.Peer-Reviewed Original ResearchConceptsIncident atrial fibrillationPosttraumatic stress disorderMiddle-aged veteransAtrial fibrillationRisk factorsMultivariate Cox proportional hazards modelIncidence of AFCox proportional hazards modelStress disorderAF risk factorsCardiovascular risk factorsNew atrial fibrillationProspective cohort studyHigher overall incidenceVeterans Health AdministrationProportional hazards modelAcute psychological stressChronic stress syndromeCohort studyOverall incidenceAtrial tachycardiaLifestyle factorsAtrial flutterHealthcare useEffect modification
2018
Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study
Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.Peer-Reviewed Original ResearchConceptsMI-CAD patientsNonobstructive coronary arteriesMI-CADYounger patientsClinical profileCoronary arteryMyocardial infarctionTraditional cardiac risk factorsAcute myocardial infarction patientsCardiac risk factorsGestational diabetes mellitusMyocardial infarction patientsTimes higher oddsMINOCA patientsSAQ qualityVIRGO StudyClinical characteristicsHypercoaguable stateDiabetes mellitusObstructive diseaseClinical outcomesInfarction patientsRisk factorsMINOCAPsychosocial status
2014
Impact of Early Extubation and Reintubation on the Incidence of Bronchopulmonary Dysplasia in Neonates
Berger J, Mehta P, Bucholz E, Dziura J, Bhandari V. Impact of Early Extubation and Reintubation on the Incidence of Bronchopulmonary Dysplasia in Neonates. American Journal Of Perinatology 2014, 31: 1063-1072. PMID: 24683068, DOI: 10.1055/s-0034-1371702.Peer-Reviewed Original ResearchMeSH KeywordsAirway ExtubationApgar ScoreBirth WeightBronchopulmonary DysplasiaDisease-Free SurvivalDuctus Arteriosus, PatentFemaleGestational AgeHumansIncidenceInfant, NewbornIntracranial HemorrhagesIntubation, IntratrachealKaplan-Meier EstimateMaleProportional Hazards ModelsRespiratory Distress Syndrome, NewbornRetinopathy of PrematurityRetreatmentRetrospective StudiesTime Factors
2012
Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug
Jovin IS, Duggal M, Ebisu K, Paek H, Oprea AD, Tranquilli M, Rizzo J, Memet R, Feldman M, Dziura J, Brandt CA, Elefteriades JA. Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug. The American Journal Of Cardiology 2012, 109: 1050-1054. PMID: 22221941, DOI: 10.1016/j.amjcard.2011.11.038.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmLong-term outcomesComposite end pointAortic aneurysmAneurysm repairEnd pointImproved long-term outcomesOutcomes of patientsCohort of patientsKaplan-Meier analysisMedian followStatin intakeStatin therapyMedical therapyStatinsFirst presentationPatientsSurvival rateAneurysmsStatin drugsOutcomesTherapyIntakeRepairCohort
2011
Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography for Obstructing Pancreas Head Masses
Aslanian HR, Estrada JD, Rossi F, Dziura J, Jamidar PA, Siddiqui UD. Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography for Obstructing Pancreas Head Masses. Journal Of Clinical Gastroenterology 2011, 45: 711-713. PMID: 21301359, DOI: 10.1097/mcg.0b013e3182045923.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnesthesia, GeneralBiopsy, Fine-NeedleChi-Square DistributionCholangiopancreatography, Endoscopic RetrogradeConnecticutConscious SedationDrainageEndosonographyFeasibility StudiesHumansJaundice, ObstructiveMiddle AgedPancreatic NeoplasmsPredictive Value of TestsRetrospective StudiesStentsTime FactorsTreatment OutcomeConceptsEndoscopic retrograde cholangiopancreatographyEndoscopic ultrasoundFine-needle aspirationObstructive jaundiceRetrograde cholangiopancreatographyStent placementEUS-FNAEUS-guided fine-needle aspirationPancreas head massTertiary referral hospitalBiliary stent placementEUS-FNA diagnosisDiagnostic EUS-FNAPlacement success rateOnly complicationReferral hospitalSedative medicationsBiliary stentingConsecutive patientsMedian timePatient evaluationERCP proceduresSame sedationProcedure durationProcedure lengthLong-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population
Savoye M, Nowicka P, Shaw M, Yu S, Dziura J, Chavent G, O'Malley G, Serrecchia JB, Tamborlane WV, Caprio S. Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population. Pediatrics 2011, 127: 402-410. PMID: 21300674, PMCID: PMC3065145, DOI: 10.1542/peds.2010-0697.Peer-Reviewed Original ResearchConceptsControl groupLow-density lipoprotein cholesterolTotal body fat massIntensive lifestyle programIntensive lifestyle interventionHomeostasis model assessmentActive intervention phaseWeight management programBody fat massLong-term resultsBMI z-scorePercent body fatDiverse pediatric populationFamily-based programsLifestyle interventionLipoprotein cholesterolTotal cholesterolObese childrenObese populationPediatric populationInsulin resistanceObesity programLifestyle programFat massIntervention group
2009
Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia
Kadan-Lottick NS, Brouwers P, Breiger D, Kaleita T, Dziura J, Northrup V, Chen L, Nicoletti M, Bostrom B, Stork L, Neglia JP. Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia. Journal Of Clinical Oncology 2009, 27: 5986-5992. PMID: 19884541, PMCID: PMC2793042, DOI: 10.1200/jco.2009.23.5408.Peer-Reviewed Original ResearchMeSH KeywordsAntimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsAttentionChildChild, PreschoolCognitionCross-Sectional StudiesCytarabineFemaleHumansHydrocortisoneInfantInjections, SpinalIntelligence TestsLinear ModelsMaleMemoryMethotrexateNeuropsychological TestsPrecursor Cell Lymphoblastic Leukemia-LymphomaPsychomotor PerformanceTime FactorsTreatment OutcomeUnited StatesConceptsAcute lymphoblastic leukemiaIT therapyIntrathecal methotrexateMethotrexate groupLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaTriple intrathecal therapyPost-therapy periodLong-term neurotoxicityNeurocognitive functioningAssociation of treatmentMajority of childrenCNS prophylaxisFull-scale intelligence quotientIntrathecal therapyNeurologic eventsPsychotropic medicationsVisual-motor integrationTherapy groupAttention/concentrationNeurocognitive evaluationIndex scoreTherapyPatientsMethotrexateSpecific Relation Between Abdominal Obesity and Early-Phase Hyperglycemia Is Modulated by Hepatic Insulin Resistance in Healthy Older Women
DiPietro L, Dziura J, Yeckel CW. Specific Relation Between Abdominal Obesity and Early-Phase Hyperglycemia Is Modulated by Hepatic Insulin Resistance in Healthy Older Women. Diabetes Care 2009, 33: 165-167. PMID: 19808930, PMCID: PMC2797964, DOI: 10.2337/dc09-1365.Peer-Reviewed Original ResearchConceptsHepatic insulin resistanceOral glucose tolerance testAbdominal obesityGlucose tolerance testHealthy older womenInsulin resistanceOlder womenTolerance testLow-dose insulin infusionHepatic glucose productionGlucose excursionsInsulin infusionPlasma glucoseAbdominal circumferenceInsulin concentrationsInsulin suppressionMin postchallengeObesityGlycemic responseClamp techniqueGlucose productionWomenHyperglycemiaProduction suppressionPostchallenge
2008
Progressive improvement in glucose tolerance following lower-intensity resistance versus moderate-intensity aerobic training in older women.
Dipietro L, Yeckel CW, Dziura J. Progressive improvement in glucose tolerance following lower-intensity resistance versus moderate-intensity aerobic training in older women. Journal Of Physical Activity And Health 2008, 5: 854-69. PMID: 19164820, DOI: 10.1123/jpah.5.6.854.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testFree fatty acidsGlucose toleranceOlder womenFFA concentrationsModerate-intensity aerobic trainingBasal FFA concentrationLight resistance trainingModerate-intensity aerobicLast exercise sessionGlucose tolerance testInactive older womenResistance training groupLevels of FFALow-intensity resistanceTolerance testPlasma glucoseAerobic trainingExercise sessionsSerial improvementInsulin actionOlder peopleTraining groupProgressive improvementGlucose concentrationSocioeconomic predictors of weight loss after laparoscopic Roux-Y gastric bypass
Akkary E, Nerlinger A, Yu S, Dziura J, Duffy AJ, Bell RL. Socioeconomic predictors of weight loss after laparoscopic Roux-Y gastric bypass. Surgical Endoscopy 2008, 23: 1246-1251. PMID: 18813989, DOI: 10.1007/s00464-008-0138-z.Peer-Reviewed Original ResearchConceptsBody mass indexInitial body mass indexPostoperative weight lossWeight lossLaparoscopic RouxBMI decreaseSocioeconomic statusInitial mean body mass indexMedian household incomeMean body mass indexPrivate insuranceAppropriate patient selectionPrivate insurance groupPostoperative behavioral changesInsurance carriersProspective databaseGastric bypassPatient demographicsSingle surgeonMass indexPatient selectionGroup APatientsLRYGBHousehold incomeThe paradox of the pouch: prompt emptying predicts improved weight loss after laparoscopic Roux-Y gastric bypass
Akkary E, Sidani S, Boonsiri J, Yu S, Dziura J, Duffy AJ, Bell RL. The paradox of the pouch: prompt emptying predicts improved weight loss after laparoscopic Roux-Y gastric bypass. Surgical Endoscopy 2008, 23: 790. PMID: 18806946, DOI: 10.1007/s00464-008-0069-8.Peer-Reviewed Original ResearchConceptsWeight lossGastric bypassLaparoscopic RouxOperative timeGastric pouchSlow emptyingAnalysis of covarianceBody mass index lossLinear stapler techniqueUpper gastrointestinal evaluationGroup B patientsPostoperative day 1Postoperative weight lossInfluences weight lossLength of stayMore weight lossAnastomotic edemaUGI studiesProspective databaseRate of contrastB patientsGastrointestinal evaluationPatient demographicsSingle surgeonNormal gastric
2007
A Randomized Trial to Assess the Efficacy of Point-of-Care Testing in Decreasing Length of Stay in a Pediatric Emergency Department
Hsiao AL, Santucci KA, Dziura J, Baker MD. A Randomized Trial to Assess the Efficacy of Point-of-Care Testing in Decreasing Length of Stay in a Pediatric Emergency Department. Pediatric Emergency Care 2007, 23: 457-462. PMID: 17666926, DOI: 10.1097/01.pec.0000280506.44924.de.Peer-Reviewed Original ResearchConceptsPediatric emergency departmentLength of stayEmergency departmentPOC groupTertiary hospital emergency departmentDedicated research assistantsFirst physician contactTrial of patientsPatient flowSelect pediatric patientsHospital emergency departmentCare testingEfficacy of pointMedical management decisionsPhysician contactPediatric patientsBlood workRandomized trialsED settingBlood drawPatientsInformed consentStayPOC testingSignificant decreaseMethodological issues in design and analysis of a matched case–control study of a vaccine's effectiveness
Niccolai LM, Ogden LG, Muehlenbein CE, Dziura JD, Vázquez M, Shapiro ED. Methodological issues in design and analysis of a matched case–control study of a vaccine's effectiveness. Journal Of Clinical Epidemiology 2007, 60: 1127-1131. PMID: 17938054, PMCID: PMC2096633, DOI: 10.1016/j.jclinepi.2007.02.009.Peer-Reviewed Original ResearchConceptsCase-control studyTime of vaccinationConditional logistic regression modelsPrelicensure clinical trialsLogistic regression modelsVaricella vaccineVaccine effectivenessVaccine efficacyClinical trialsVaccinationVaccineStudy designRegression modelsEfficacyAgeEffect of timeMethodological issuesTrialsPreanesthesia Clinics, Information Management, and Operating Room Delays: Results of a Survey of Practicing Anesthesiologists
Holt NF, Silverman DG, Prasad R, Dziura J, Ruskin KJ. Preanesthesia Clinics, Information Management, and Operating Room Delays: Results of a Survey of Practicing Anesthesiologists. Anesthesia & Analgesia 2007, 104: 615-618. PMID: 17312219, DOI: 10.1213/01.ane.0000255253.62668.3a.Peer-Reviewed Original ResearchConceptsSurgery delayPercent of respondentsPreanesthesia evaluationSingle-center studyDay of surgeryOperating room delaysIncidence of daysPreanesthesia clinicEvaluation clinicSurgical readinessNational prevalencePatientsSurgeryPrevalence of dayLack of consensusPatient informationOverall usePracticing anesthesiologistsAmerican SocietyClinicAnesthesiologistsPrevalenceVisitsDaysPossible causes
2006
Is It Safe to Delay Appendectomy in Adults With Acute Appendicitis?
Ditillo MF, Dziura JD, Rabinovici R. Is It Safe to Delay Appendectomy in Adults With Acute Appendicitis? Annals Of Surgery 2006, 244: 656-660. PMID: 17060754, PMCID: PMC1856602, DOI: 10.1097/01.sla.0000231726.53487.dd.Peer-Reviewed Original ResearchConceptsAcute appendicitisOnset of symptomsAdvanced pathologyAdult patientsPrompt appendectomyPostoperative complicationsEmergency roomAntibiotic treatmentProgressive pathologyRight lower quadrantRisk of progressionLength of stayStandard of careGangrenous acute appendicitisHigher pathology gradeTotal intervalDegree of pathologyElective mannerHospital intervalHospital delayHospital stayAntibiotic therapyPediatric patientsRetrospective reviewPathologic findingsWait-and-See Prescription for the Treatment of Acute Otitis Media: A Randomized Controlled Trial
Spiro DM, Tay KY, Arnold DH, Dziura JD, Baker MD, Shapiro ED. Wait-and-See Prescription for the Treatment of Acute Otitis Media: A Randomized Controlled Trial. JAMA 2006, 296: 1235-1241. PMID: 16968847, DOI: 10.1001/jama.296.10.1235.Peer-Reviewed Original ResearchConceptsAcute otitis mediaEmergency departmentAntibiotic prescriptionsOtitis mediaTreatment of AOMSevere acute otitis mediaUse of antibioticsClinical courseCommon diagnosisControlled TrialsClinical symptomsAdverse outcomesSubsequent feverAntibiotic useInterview 4Medical careUnnecessary useSP groupRoutine usePatientsPrevious trialsTrialsGroup assignmentAntibioticsOtalgiaEarly postoperative arrhythmias after pediatric cardiac surgery
Delaney JW, Moltedo JM, Dziura JD, Kopf GS, Snyder CS. Early postoperative arrhythmias after pediatric cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2006, 131: 1296-1300. PMID: 16733160, DOI: 10.1016/j.jtcvs.2006.02.010.Peer-Reviewed Original ResearchConceptsAortic crossclamp timeEarly postoperative arrhythmiasPediatric cardiac surgeryCrossclamp timeCardiac surgeryAtrioventricular septal defectPostoperative arrhythmiasBypass timeSeptal defectRisk factorsCalcium levelsRe-entrant supraventricular tachycardiaAtrioventricular septal defect repairCardiopulmonary bypass timeJunctional ectopic tachycardiaSeptal defect repairComplete atrioventricular blockDevelopment of arrhythmiasNonarrhythmia groupsEctopic tachycardiaFrequent complicationPediatric patientsSignificant arrhythmiasAtrioventricular blockCardiopulmonary bypassAmylase‐Resistant Starch as Adjunct to Oral Rehydration Therapy in Children with Diarrhea
Raghupathy P, Ramakrishna BS, Oommen SP, Ahmed MS, Priyaa G, Dziura J, Young GP, Binder HJ. Amylase‐Resistant Starch as Adjunct to Oral Rehydration Therapy in Children with Diarrhea. Journal Of Pediatric Gastroenterology And Nutrition 2006, 42: 362-368. PMID: 16641573, DOI: 10.1097/01.mpg.0000214163.83316.41.Peer-Reviewed Original ResearchConceptsOral rehydration solutionAmylase-resistant starchGlucose-ORSDuration of diarrheaStool weightAcute diarrheaStandard treatmentFluid absorptionG-ORS groupMean stool weightIntravenous fluid therapyAcute watery diarrheaOral rehydration therapySeverity of diarrheaTreatment of diarrheaShort-chain fatty acidsColonic sodiumEvaluable dataRehydration therapyTreatment failureFluid therapyWatery diarrheaRehydration solutionIntestinal sodiumDiarrhea