2021
A case study of ascertainment bias for the primary outcome in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial
Esserman DA, Gill TM, Miller ME, Greene EJ, Dziura JD, Travison TG, Meng C, Peduzzi PN. A case study of ascertainment bias for the primary outcome in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial. Clinical Trials 2021, 18: 207-214. PMID: 33678038, PMCID: PMC8009806, DOI: 10.1177/1740774520980070.Peer-Reviewed Original ResearchConceptsPrimary outcome definitionUsual care armSerious fall injuriesMedical attentionOutcome definitionsFall injuriesElders trialCare armOvernight hospitalizationStudy powerCare managersIntervention effectsType 2 injuriesAscertainment biasAscertainment of outcomesInterim monitoring planUsual careHazard ratioPrimary outcomeIntervention armClinical trialsUnblinded observerClinical basisMulticomponent interventionAdditional fall
2017
Tobacco dependence treatment in the emergency department: A randomized trial using the Multiphase Optimization Strategy
Bernstein SL, Dziura J, Weiss J, Miller T, Vickerman KA, Grau LE, Pantalon MV, Abroms L, Collins LM, Toll B. Tobacco dependence treatment in the emergency department: A randomized trial using the Multiphase Optimization Strategy. Contemporary Clinical Trials 2017, 66: 1-8. PMID: 29287665, PMCID: PMC5851600, DOI: 10.1016/j.cct.2017.12.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultCost-Benefit AnalysisEmergency Service, HospitalFemaleHotlinesHumansMaleMiddle AgedMotivational InterviewingNicotine Chewing GumQualitative ResearchQuality-Adjusted Life YearsReferral and ConsultationSmoking CessationSmoking Cessation AgentsText MessagingTobacco Use Cessation DevicesTobacco Use DisorderTransdermal PatchTreatment OutcomeUnited StatesConceptsExhaled carbon monoxideHospital emergency departmentEmergency departmentMultiphase optimization strategyTobacco dependenceSubsequent confirmatory trialTobacco dependence interventionsNicotine replacement therapyTobacco dependence treatmentRecent clinical trialsLower socioeconomic groupsCost-effectiveness analysisPrimary endpointED patientsInitial treatmentStudy enrollmentTelephone quitlinesClinical efficacyPreventable causeReplacement therapyFuture trialsDependence treatmentTobacco abstinenceClinical trialsMulticomponent intervention