1978
Validation of 13CO2 breath analysis as a measurement of demethylation of stable isotope labeled aminopyrine in man
Schneider J, Schoeller D, Nemchausky B, Boyer J, Klein P. Validation of 13CO2 breath analysis as a measurement of demethylation of stable isotope labeled aminopyrine in man. Clinica Chimica Acta 1978, 84: 153-162. PMID: 639299, DOI: 10.1016/0009-8981(78)90489-8.Peer-Reviewed Original ResearchConceptsLiver diseaseHepatic microsomal drug metabolismMicrosomal drug metabolismSimultaneous oral administrationDrug-drug interactionsNon-invasive assessmentN-demethylation activityOral doseCumulative excretionOral administrationEffects of diseaseExcretion of labelAdult subjectsDrug metabolismDiseaseExpired breathCumulative appearanceHuman subjectsPatientsReproducible increaseAminopyrineRadiation riskExcretionSubjectsHours
1970
Canalicular Bile flow and Bile Secretory Pressure Evidence for a non-bile salt dependent fraction in the isolated perfused rat liver
Boyer J, Klatskin G. Canalicular Bile flow and Bile Secretory Pressure Evidence for a non-bile salt dependent fraction in the isolated perfused rat liver. Gastroenterology 1970, 59: 853-859. PMID: 5486271, DOI: 10.1016/s0016-5085(19)33645-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBileBile Acids and SaltsCarbon IsotopesCommon Bile DuctLiverMannitolPerfusionPressureRats
1969
Hepatic metabolism of 1‐14C octanoic and 1‐14C margaric acids
Boyer J, Scheig R. Hepatic metabolism of 1‐14C octanoic and 1‐14C margaric acids. Lipids 1969, 4: 615-617. PMID: 5367946, DOI: 10.1007/bf02531049.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarbon IsotopesFatty AcidsGlyceridesKineticsLiverPalmitic AcidsPhospholipidsRatsTriglycerides