1997
ATP regulation of a swelling‐activated osmolyte channel in skate hepatocytes
Ballatori N, Boyer J. ATP regulation of a swelling‐activated osmolyte channel in skate hepatocytes. Journal Of Experimental Zoology 1997, 279: 471-475. PMID: 9392868, DOI: 10.1002/(sici)1097-010x(19971201)279:5<471::aid-jez9>3.0.co;2-l.Peer-Reviewed Original ResearchConceptsChannel blockersTaurine effluxRegulatory volume decreaseVolume-activated taurine effluxRelease of taurineSkate hepatocytesIntracellular ATPIon channel blockersChloride permeability ratioIntracellular ATP levelsControl levelsOsmolyte channelIntracellular organic osmolytesWhole cell preparationsCell preparationsATP levelsBlockersHypotonic swellingChannel openingHepatocytesVolume decreaseAdditional mechanismEfflux
1995
ATP depletion and inactivation of an ATP-sensitive taurine channel by classic ion channel blockers.
Ballatori N, Truong A, Jackson P, Strange K, Boyer J. ATP depletion and inactivation of an ATP-sensitive taurine channel by classic ion channel blockers. Molecular Pharmacology 1995, 48: 472-6. PMID: 7565627.Peer-Reviewed Original ResearchConceptsIon channel blockersChannel blockersVolume-activated anion channelsATP levelsATP contentActivity of ATPPhysiologic alterationsIntracellular ATP levelsCellular ATPTaurine effluxBlockersIntracellular ATP contentTaurine channelCellular ATP levelsATP/ADP ratioIntracellular organic osmolytesSkate hepatocytesIntracellular ATPATP depletionCell volume regulationDifferent cell typesEffluxCellular ATP concentrationMetabolic poisonsCell types
1994
A volume-activated taurine channel in skate hepatocytes: membrane polarity and role of intracellular ATP
Ballatori N, Simmons T, Boyer J. A volume-activated taurine channel in skate hepatocytes: membrane polarity and role of intracellular ATP. American Journal Of Physiology 1994, 267: g285-g291. PMID: 7521136, DOI: 10.1152/ajpgi.1994.267.2.g285.Peer-Reviewed Original ResearchConceptsCell swellingSkate hepatocytesIntracellular ATPExtracellular taurine concentrationMetabolic inhibitorsSinusoidal circulationHypotonic stimuliTaurine concentrationsTaurine effluxTaurine uptakeIndependent uptakeTaurine channelSkate liverEfflux mechanismTaurineLiverHepatocytesInhibitorsEffluxBasolateral membraneOsmolyte taurineSwellingAntimycin ADisulfonic acidTransport inhibitors