2023
Aging gene signature of memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer’s disease
Young J, Park H, Kim M, Par-Young J, Bartlett H, Kim H, Unlu S, Osmani L, Shin M, Bucala R, van Dyck C, Allore H, Mecca A, You S, Kang I. Aging gene signature of memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer’s disease. Immunity & Ageing 2023, 20: 71. PMID: 38042785, PMCID: PMC10693128, DOI: 10.1186/s12979-023-00396-y.Peer-Reviewed Original ResearchPeripheral bloodT cellsAlzheimer's diseaseEM CD8Memory CD8Gene signatureAge-related immune changesIL-7 receptor alphaEffector memory CD8Strong risk factorT cell expansionAD genesAge-associated expansionImmune changesRisk factorsCD8Dementia patientsIL-7RNeuropsychological testingReceptor alphaNeurocognitive functionRT-qPCR resultsDisease severityPatientsNormal persons
2003
Infectious complications in SLE after immunosuppressive therapies
Kang I, Park S. Infectious complications in SLE after immunosuppressive therapies. Current Opinion In Internal Medicine 2003, 2: 629-635. DOI: 10.1097/00132980-200302060-00015.Peer-Reviewed Original ResearchSystemic lupus erythematosusMannose-binding lectin variant allelesHigh-dose glucocorticoidsImmunosuppressive therapyLupus erythematosusInfectious complicationsMycophenolate mofetilImmunosuppressive drugsRisk factorsVariant allelesMannose-binding lectin deficiencyMajor organ involvementUse of steroidsCommon viral infectionsExtrinsic risk factorsStrong risk factorIncidence of infectionHerpes zosterOrgan involvementSerious infectionsLectin deficiencyErythematosusImmune responsePatientsViral infectionInfectious complications in SLE after immunosuppressive therapies
Kang I, Park S. Infectious complications in SLE after immunosuppressive therapies. Current Opinion In Internal Medicine 2003, 2: 629-635. DOI: 10.1097/00132980-200312000-00015.Peer-Reviewed Original ResearchSystemic lupus erythematosusMannose-binding lectin variant allelesHigh-dose glucocorticoidsImmunosuppressive therapyLupus erythematosusInfectious complicationsMycophenolate mofetilImmunosuppressive drugsRisk factorsVariant allelesMannose-binding lectin deficiencyMajor organ involvementUse of steroidsCommon viral infectionsExtrinsic risk factorsStrong risk factorIncidence of infectionHerpes zosterOrgan involvementSerious infectionsLectin deficiencyErythematosusImmune responsePatientsViral infection