2018
Interleukin-1 and IL-23 induce innate-like immune responses by bystander-activated memory CD4+ T cells contributing to the autoimmune pathogenesis
Lee H, Lee J, Kang I, Choi J. Interleukin-1 and IL-23 induce innate-like immune responses by bystander-activated memory CD4+ T cells contributing to the autoimmune pathogenesis. The Journal Of Immunology 2018, 200: 51.7-51.7. DOI: 10.4049/jimmunol.200.supp.51.7.Peer-Reviewed Original ResearchT cellsT cell antigen receptorIL-17AIL-23Memory CD4IL-1βImmune responseAutoimmune disease pathogenesisPro-inflammatory cytokinesIFN-γ expressionNaïve T cellsT cell activationAutoimmune neuroinflammationImmunopathological roleTh17 cellsAutoimmune pathogenesisBystander activationBystander CD4T lymphocytesIL-1Interleukin-1CD4Disease pathogenesisCell activationCell antigen receptor
2012
Altered Th17 and Th1 cells responses in patients with primary Sjogren syndrome (59.10)
Kang G, Kim S, Bunin V, Shin M, Lee N, Parke A, Kang I. Altered Th17 and Th1 cells responses in patients with primary Sjogren syndrome (59.10). The Journal Of Immunology 2012, 188: 59.10-59.10. DOI: 10.4049/jimmunol.188.supp.59.10.Peer-Reviewed Original ResearchPrimary Sjogren's syndromeHealthy subjectsIL-7IL-17IL-23Sjogren's syndromeIL-10IL-12Peripheral bloodIL-1βIL-6Th1 cellsTh1-polarizing cytokine IL-12Anti-inflammatory cytokine IL-10Frequencies of Th17Frequency of CD4Cytokine IL-10IL-10 productionSystemic autoimmune diseaseCytokines IL-12IL-12 productionInnate immune cellsMajor proinflammatory cytokineSupernatants of lipopolysaccharideDry mouth