1989
Regulation of active sodium and potassium transport in the distal colon of the rat. Role of the aldosterone and glucocorticoid receptors.
Turnamian S, Binder H. Regulation of active sodium and potassium transport in the distal colon of the rat. Role of the aldosterone and glucocorticoid receptors. Journal Of Clinical Investigation 1989, 84: 1924-1929. PMID: 2592566, PMCID: PMC304073, DOI: 10.1172/jci114380.Peer-Reviewed Original ResearchConceptsElectrogenic sodium absorptionReceptor-specific agonistsSodium absorptionAldosterone receptorsRU 28362Continuous infusionDistal colonGlucocorticoid receptorAmiloride-sensitive sodium absorptionColonic electrolyte transportEffects of aldosteroneRat distal colonPotassium transportActive sodiumPotassium secretionAldosteroneSustained increasePotassium absorptionAgonistsReceptorsElectrolyte transportGlucocorticoidsUnidirectional NaInfusionColon
1988
Electrolyte transport in distal colon of sodium-depleted rats: effect of sodium repletion
Turnamian S, Binder H. Electrolyte transport in distal colon of sodium-depleted rats: effect of sodium repletion. American Journal Of Physiology 1988, 255: g329-g338. PMID: 2844099, DOI: 10.1152/ajpgi.1988.255.3.g329.Peer-Reviewed Original ResearchConceptsElectrogenic sodium absorptionElectroneutral sodium chloride absorptionPlasma aldosterone levelsAldosterone levelsSodium chloride absorptionPotassium secretionSodium absorptionSodium repletionDistal colonChloride absorptionElevated plasma aldosterone levelsSodium depletion increasesDistal colonic mucosaSodium-depleted ratsElectroneutral sodium absorptionRat distal colonExcess aldosteroneVoltage-clamp conditionsDietary sodiumColonic mucosaNormal animalsUnidirectional 22NaATPase activityElectrolyte transportSecretion
1986
Role of Aldosterone in the Regulation of Sodium and Chloride Transport in the Distal Colon of Sodium-Depleted Rats
Halevy J, Budinger M, Hayslett J, Binder H. Role of Aldosterone in the Regulation of Sodium and Chloride Transport in the Distal Colon of Sodium-Depleted Rats. Gastroenterology 1986, 91: 1227-1233. PMID: 3758615, DOI: 10.1016/s0016-5085(86)80021-x.Peer-Reviewed Original ResearchConceptsElectroneutral sodium chloride absorptionElectrogenic sodium absorptionSodium chloride absorptionRole of aldosteroneSodium-depleted animalsSodium absorptionChloride absorptionAldosterone infusionDistal colonPotassium secretionAmiloride-sensitive sodium absorptionContinuous aldosterone infusionDietary sodium depletionDistal colonic mucosaElevated aldosterone levelsActive potassium secretionRat distal colonAddition of amilorideRegulation of sodiumVoltage-clamp conditionsAldosterone levelsTime-dependent mannerSodium depletionColonic mucosaAldosteroneSodium and chloride transport in the large intestine of potassium-loaded rats
Budinger M, Foster E, Hayslett J, Binder H. Sodium and chloride transport in the large intestine of potassium-loaded rats. American Journal Of Physiology 1986, 251: g249-g252. PMID: 2426972, DOI: 10.1152/ajpgi.1986.251.2.g249.Peer-Reviewed Original ResearchConceptsPotassium secretionSodium absorptionRat distal colonic mucosaElectroneutral sodium chloride absorptionPotassium loadingNa-K-ATPase activityElectrogenic sodium absorptionDistal colonic mucosaActive potassium secretionPotassium-loaded ratsNet sodium absorptionSodium chloride absorptionActive sodium transportVoltage-clamp conditionsDietary potassiumColonic functionColonic mucosaNet chloride fluxNet sodium fluxJNanetNet sodiumLarge intestineChloride fluxSodium transportIdentical increase