2023
Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication
Altin S, Parise H, Hess C, Rosenthal N, Creager M, Aronow H, Curtis J. Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication. JACC Cardiovascular Interventions 2023, 16: 1668-1678. PMID: 37438035, DOI: 10.1016/j.jcin.2023.05.001.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsIndex limb amputationAmputation rateIntermittent claudicationMajor amputationRevascularization ratesVascular interventionsCox proportional hazards regressionLong-term patient outcomesMajor amputation rateProportional hazards regressionKaplan-Meier estimatesFurther risk factorsLimb amputation rateClinical trial dataIndex limbIC patientsSecondary outcomesPrimary outcomeHazards regressionRisk factorsPatient outcomesLimb amputationHealthcare databasesPatients
2014
Impact of Coronary Lesion Complexity on Drug-Eluting Stent Outcomes in Patients With and Without Diabetes Mellitus Analysis From 18 Pooled Randomized Trials
Kedhi E, Généreux P, Palmerini T, McAndrew T, Parise H, Mehran R, Dangas G, Stone G. Impact of Coronary Lesion Complexity on Drug-Eluting Stent Outcomes in Patients With and Without Diabetes Mellitus Analysis From 18 Pooled Randomized Trials. Journal Of The American College Of Cardiology 2014, 63: 2111-2118. PMID: 24632279, DOI: 10.1016/j.jacc.2014.01.064.Peer-Reviewed Original ResearchConceptsDiabetes mellitusRepeat revascularizationMyocardial infarctionLesion complexityStent outcomesCardiac deathType A/B1 lesionsType B2/C lesionsB2/C lesionsPropensity score-matched groupsCoronary lesion complexityTarget vessel revascularizationPatient-level dataB1 lesionsNoncomplex lesionsVessel revascularizationDiabetic statusC lesionsDES eraRandomized trialsRisk factorsTarget lesionsDES safetyTreatment outcomesBaseline differences
2013
Evaluating the clinical usefulness of platelet function testing: Considerations for the proper application and interpretation of performance measures
Dahlen J, Price M, Parise H, Gurbel P. Evaluating the clinical usefulness of platelet function testing: Considerations for the proper application and interpretation of performance measures. Thrombosis And Haemostasis 2013, 109: 808-816. PMID: 23254993, DOI: 10.1160/th12-08-0608.Peer-Reviewed Original ResearchConceptsPlatelet function testingFunction testingClinical usefulnessP2Y12 inhibitorsPharmacodynamic effectsPredictive valueFuture thrombotic eventsRate of thrombosisManagement of patientsPlatelet function testsNet reclassification improvementDiagnostic performance indicatorsPlatelet P2Y12 receptorPositive predictive valueDiagnostic performance measuresCardiovascular eventsHazard ratioThrombotic eventsRisk stratificationFunction testsPrognostic utilityAntiplatelet effectReclassification improvementRisk factorsP2Y12 receptor
2011
INCIDENCE AND RISK FACTORS FOR CONTRAST-INDUCED NEPHROPATHY IN PRIMARY PERCUTANEOUS CORONARY INTERVENTION: AN ANALYSIS FROM THE HARMONIZING OUTCOMES WITH REVASCULARIZATION AND STENTS IN ACUTE MYOCARDIAL INFARCTION TRIAL (HORIZONS-AMI)
Narula A, Weisz G, Dangas G, Clausen B, Saltzman A, Kornowski R, Brodie B, Dudek D, Nikolsky E, Witzenbichler B, Guagliumi G, Fahy M, Parise H, Stone G, Mehran R. INCIDENCE AND RISK FACTORS FOR CONTRAST-INDUCED NEPHROPATHY IN PRIMARY PERCUTANEOUS CORONARY INTERVENTION: AN ANALYSIS FROM THE HARMONIZING OUTCOMES WITH REVASCULARIZATION AND STENTS IN ACUTE MYOCARDIAL INFARCTION TRIAL (HORIZONS-AMI). Journal Of The American College Of Cardiology 2011, 57: e1061. DOI: 10.1016/s0735-1097(11)61061-9.Peer-Reviewed Original Research
2007
Pulse Pressure and Risk of New-Onset Atrial Fibrillation
Mitchell G, Vasan R, Keyes M, Parise H, Wang T, Larson M, D’Agostino R, Kannel W, Levy D, Benjamin E. Pulse Pressure and Risk of New-Onset Atrial Fibrillation. JAMA 2007, 297: 709-715. PMID: 17312290, DOI: 10.1001/jama.297.7.709.Peer-Reviewed Original ResearchConceptsIncident atrial fibrillationMean arterial pressureAtrial fibrillationPulse pressureRisk factorsArterial pressureCommunity-based observational cohortNew-onset atrial fibrillationIncidence of AFAF incidence ratesClinical risk factorsModifiable risk factorsVentricular fractional shorteningFramingham Heart Study participantsImportant risk factorCommunity-based sampleAtrial dimensionObservational cohortAortic stiffnessConsiderable morbidityFractional shorteningSystolic pressureAF riskDiastolic pressureVentricular mass
2005
Cross-Sectional Relations of Peripheral Microvascular Function, Cardiovascular Disease Risk Factors, and Aortic Stiffness
Mitchell G, Vita J, Larson M, Parise H, Keyes M, Warner E, Vasan R, Levy D, Benjamin E. Cross-Sectional Relations of Peripheral Microvascular Function, Cardiovascular Disease Risk Factors, and Aortic Stiffness. Circulation 2005, 112: 3722-3728. PMID: 16330686, DOI: 10.1161/circulationaha.105.551168.Peer-Reviewed Original ResearchConceptsCarotid-femoral pulse wave velocityCardiovascular disease risk factorsDisease risk factorsBrachial pulse pressureMean arterial pressureAortic stiffnessAortic wall stiffnessRisk factorsArterial pressurePulse pressureBlood flowConventional cardiovascular disease risk factorsHyperemic forearm blood flowRisk factor-adjusted modelsFramingham Heart Study Offspring CohortAbnormal aortic stiffnessForearm blood flowBrachial artery diameterPeripheral microvascular functionForward pressure wave amplitudePulse wave velocitySmall artery structureHigh-resolution ultrasoundWall stiffnessMicrovascular reactivity
2004
Obesity and the Risk of New-Onset Atrial Fibrillation
Wang T, Parise H, Levy D, D’Agostino R, Wolf P, Vasan R, Benjamin E. Obesity and the Risk of New-Onset Atrial Fibrillation. JAMA 2004, 292: 2471-2477. PMID: 15562125, DOI: 10.1001/jama.292.20.2471.Peer-Reviewed Original ResearchConceptsBody mass indexNew-onset atrial fibrillationEchocardiographic left atrial diameterLeft atrial diameterAtrial fibrillationRisk factorsAtrial diameterBMI categoriesMass indexAF riskCommunity-based observational cohortNormal body mass indexAge-adjusted incidence ratesInterim myocardial infarctionCardiovascular risk factorsVentricular diastolic dysfunctionBaseline atrial fibrillationClinical risk factorsModifiable risk factorsInfluence of obesityDiastolic dysfunctionAtrial dilatationAtrial dimensionClinical confoundersHazard ratioLocal Shear Stress and Brachial Artery Flow–Mediated Dilation
Mitchell G, Parise H, Vita J, Larson M, Warner E, Keaney J, Keyes M, Levy D, Vasan R, Benjamin E. Local Shear Stress and Brachial Artery Flow–Mediated Dilation. Hypertension 2004, 44: 134-139. PMID: 15249547, DOI: 10.1161/01.hyp.0000137305.77635.68.Peer-Reviewed Original ResearchConceptsHyperemic shear stressFlow-mediated dilationBrachial artery flow-mediated dilationArtery flow-mediated dilationRisk factorsPercent dilationBrachial arteryMultivariable analysisReactive hyperemiaEndothelium-dependent flow-mediated dilationCardiovascular disease risk factorsLipid medication useLocal endothelial dysfunctionStepwise multivariable analysisHormone replacement therapyMean arterial pressureDisease risk factorsBrachial artery flowPostischemic reactive hyperemiaBody mass indexSex-adjusted modelsFramingham Offspring StudyHigh-resolution ultrasoundArtery responsesEndothelial dysfunctionParental Atrial Fibrillation as a Risk Factor for Atrial Fibrillation in Offspring
Fox C, Parise H, D'Agostino R, Lloyd-Jones D, Vasan R, Wang T, Levy D, Wolf P, Benjamin E. Parental Atrial Fibrillation as a Risk Factor for Atrial Fibrillation in Offspring. JAMA 2004, 291: 2851-2855. PMID: 15199036, DOI: 10.1001/jama.291.23.2851.Peer-Reviewed Original ResearchConceptsAtrial fibrillationOffspring participantsNew-onset atrial fibrillationPopulation-based epidemiologic studyAntecedent myocardial infarctionCommon cardiac dysrhythmiaProspective cohort studyYears of ageFramingham Heart StudyFamilial atrial fibrillationCohort studyHeart failureCardiac dysrhythmiasMyocardial infarctionOriginal cohortRisk factorsEpidemiologic studiesRare caseHeart StudyGenetic susceptibilityFibrillationUnselected individualsGenetic factorsDysrhythmiasFuture risk
2002
Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience
Wilson P, D'Agostino R, Sullivan L, Parise H, Kannel W. Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience. JAMA Internal Medicine 2002, 162: 1867-1872. PMID: 12196085, DOI: 10.1001/archinte.162.16.1867.Peer-Reviewed Original ResearchConceptsAge-adjusted relative riskBody mass indexCoronary heart diseasePopulation attributable riskRelative riskCardiovascular diseaseCardiovascular sequelaeAngina pectorisExcess weightAttributable riskHeart diseaseOverweight statusRisk factorsCardiovascular disease risk factorsHighest population-attributable riskNew cardiovascular diseaseDisease risk factorsFramingham Heart Study participantsNormal-weight personsDisease end pointsNew hypertensionCardiovascular riskDiabetes mellitusPrimary outcomeMass index