2024
Longitudinal Patterns of Systolic Blood Pressure, Diastolic Blood Pressure, Cardiorespiratory Fitness, and Their Association With Dementia Risk: The HUNT Study
Lerfald M, Allore H, Nilsen T, Eldholm R, Martinez-Velilla N, Selbæk G, Ernstsen L. Longitudinal Patterns of Systolic Blood Pressure, Diastolic Blood Pressure, Cardiorespiratory Fitness, and Their Association With Dementia Risk: The HUNT Study. The Journals Of Gerontology Series A 2024, 79: glae161. PMID: 38894618, PMCID: PMC11266981, DOI: 10.1093/gerona/glae161.Peer-Reviewed Original ResearchEstimated cardiorespiratory fitnessCardiorespiratory fitnessDementia riskHUNT StudyRisk differenceAssociated with reduced dementia riskPopulation-based HUNT StudyAssociated with dementia riskOdds ratioPoor cardiorespiratory fitnessHigher cardiorespiratory fitnessRisk of dementiaEstimate odds ratiosRisk factorsModifiable risk factorsAge groupsAPOE e4 statusProspective cohort studyBlood pressureMultivariate logistic regressionHigh blood pressureMiddle-aged groupLongitudinal patternsE4 statusSystolic blood pressure
2023
Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study
Cao X, Li X, Zhang J, Sun X, Yang G, Zhao Y, Li S, Hoogendijk E, Wang X, Zhu Y, Allore H, Gill T, Liu Z. Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study. JMIR Public Health And Surveillance 2023, 9: e45502. PMID: 37200070, PMCID: PMC10236284, DOI: 10.2196/45502.Peer-Reviewed Original ResearchConceptsMultiple adverse outcomesChronic kidney diseaseDiabetes-related microvascular diseaseAdverse outcomesCause mortalityCardiovascular diseaseMiddle-aged adultsUK Biobank participantsHigh riskMicrovascular diseaseEye diseaseIncident type 2 diabetes mellitusType 2 diabetes mellitusProportional hazards regression modelsBiobank participantsMultivariable-adjusted modelsProspective cohort studyHazards regression modelsNormal glucose metabolismDiabetes-related burdenDiabetes-related diseasesHealth care resourcesNonfrail counterpartsFrailty assessmentCohort study
2022
Health literacy and physical and mental health status in octogenarian patients with coronary artery disease - a prospective cohort multicentre study
Instenes I, Brors G, Hjertvikrem N, Allore H, Borregaard B, Deaton C, Larsen A, Osborne R, Palm P, Thompson D, Norekval T. Health literacy and physical and mental health status in octogenarian patients with coronary artery disease - a prospective cohort multicentre study. European Journal Of Cardiovascular Nursing 2022, 21: zvac060.054. DOI: 10.1093/eurjcn/zvac060.054.Peer-Reviewed Original ResearchPercutaneous coronary interventionMental health statusGood health informationHealth Literacy QuestionnaireHealth literacyHealth statusHealth informationProspective cohort multicentre studyUnit increaseMental healthPhysical healthProspective cohort studyCoronary artery diseaseAdequate health literacyLow health literacyNumber of octogenariansSocial supportHealth-promoting behaviorsMyocardial Infarction Dimensional Assessment ScaleQuality of lifeOctogenarian patientsCohort studyCoronary interventionArtery diseasePCI centerFunctional Trajectories and Resilience Among Adults With Advanced Lung Cancer
Presley CJ, Arrato NA, Shields PG, Carbone DP, Wong ML, Benedict J, Reisinger SA, Han L, Gill TM, Allore H, Andersen BL, Janse S. Functional Trajectories and Resilience Among Adults With Advanced Lung Cancer. JTO Clinical And Research Reports 2022, 3: 100334. PMID: 35719868, PMCID: PMC9198463, DOI: 10.1016/j.jtocrr.2022.100334.Peer-Reviewed Original ResearchAdvanced NSCLCFunctional disabilityLung cancerBaseline Eastern Cooperative Oncology Group performance statusEastern Cooperative Oncology Group performance statusSevere disabilityPatient Health Questionnaire-9Adenocarcinoma histological subtypeDistinct functional trajectoriesAdvanced lung cancerProspective cohort studyRisk stratification toolFunctional trajectoriesLatent class trajectory modelingLung cancer treatmentWorse dyspneaBrain metastasesBaseline demographicsCohort studyFormer smokersPerformance statusBone metastasesEuroQol-5DStratification toolHistological subtypes
2021
Racial and Ethnic Differences in Multimorbidity Changes Over Time
Quiñones AR, Newsom JT, Elman MR, Markwardt S, Nagel CL, Dorr DA, Allore HG, Botoseneanu A. Racial and Ethnic Differences in Multimorbidity Changes Over Time. Medical Care 2021, 59: 402-409. PMID: 33821829, PMCID: PMC8024615, DOI: 10.1097/mlr.0000000000001527.Peer-Reviewed Original ResearchConceptsMinimal diseaseOlder adultsProspective cohort studyHigher depressive symptomsMultimorbidity combinationsEthnic older adultsCohort studyMultimorbidity patternsLung diseaseHeart diseaseRetirement Study respondentsDelay progressionDepressive symptomsMultimorbidityDiseaseLatent class analysisLatent classesEthnic differencesWhite AmericansStudy respondentsMultinomial logistic modelAdultsClass analysisLogistic modelParticipants
2010
Change in Disability After Hospitalization or Restricted Activity in Older Persons
Gill TM, Allore HG, Gahbauer EA, Murphy TE. Change in Disability After Hospitalization or Restricted Activity in Older Persons. JAMA 2010, 304: 1919-1928. PMID: 21045098, PMCID: PMC3124926, DOI: 10.1001/jama.2010.1568.Peer-Reviewed Original ResearchConceptsHazard ratioPhysical frailtySevere disabilityOlder personsMild disabilityMultivariable hazard ratiosProspective cohort studyCommunity-living personsFall-related injuriesGreater New HavenState of disabilityLikelihood of recoveryCohort studyAbsolute riskFrail individualsHospitalizationDaily livingNonfrail individualsRestricted activityInjuryTelephone interviewsFrailtyIllnessMonthsDisability