2024
Recommendations on Methods for Assessing Multimorbidity Changes Over Time: Aligning the Method to the Purpose
Nagel C, Bishop N, Botoseneanu A, Allore H, Newsom J, Dorr D, Quiñones A. Recommendations on Methods for Assessing Multimorbidity Changes Over Time: Aligning the Method to the Purpose. The Journals Of Gerontology Series A 2024, 79: glae122. PMID: 38742711, PMCID: PMC11163923, DOI: 10.1093/gerona/glae122.Peer-Reviewed Original ResearchConceptsStudy of multimorbidityHealth-related quality of lifeMeasures of multimorbidityEffect of multimorbidityPerson-centered outcomesHealth-related outcomesHealth-related qualityLongitudinal studyQuality of lifeHealth-related dataMultimorbidity researchHealth domainsMultimorbidityLate-lifePeriod of changeAging populationOperationalizing changeLongitudinal analysisLongitudinal changesMore advanced stagesQuantitative studyOutcomesResearch objectHealthPractical issues
2022
Geographic Variation in Inpatient Care Utilization, Outcomes and Costs for Dementia Patients Aged 65 Years or Older — China, 2017–2019
Lin Z, Ba F, Allore H, Liu G, Chen X. Geographic Variation in Inpatient Care Utilization, Outcomes and Costs for Dementia Patients Aged 65 Years or Older — China, 2017–2019. China CDC Weekly 2022, 4: 997-1001. PMID: 36483008, PMCID: PMC9709301, DOI: 10.46234/ccdcw2022.202.Peer-Reviewed Original ResearchPatients Aged 65 YearsDementia careInpatient care utilizationPublic health issuePublic health practicePublic health policyDementia managementCare utilizationHealthcare utilizationDisease burdenDementia patientsHealth servicesHealth practicesHealth policyHealth issuesGeographic disparitiesDementiaHealthcare systemHealthcare provisionPatientsPublic healthCareImproved accessOutcomesBurden
2020
An Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer’s Disease and Related Dementia
Quiñones AR, Kaye J, Allore HG, Botoseneanu A, Thielke SM. An Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer’s Disease and Related Dementia. American Journal Of Alzheimer's Disease & Other Dementias® 2020, 35: 1533317520960874. PMID: 32969234, PMCID: PMC7984095, DOI: 10.1177/1533317520960874.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseEthnic disparitiesMultiple chronic diseasesMultimorbidity combinationsPoor outcomeAdverse outcomesChronic diseasesHigh burdenRelated dementiaClinical treatmentDiseaseADRDU.S. populationDementia researchMultimorbidityOutcomesBurdenRiskBroad effectsPopulationDementiaDisparitiesCareCaregivers
2016
Individualized Absolute Risk Calculations for Persons with Multiple Chronic Conditions: Embracing Heterogeneity, Causality, and Competing Events
Allore H, McAvay G, Fragoso C, Murphy TE. Individualized Absolute Risk Calculations for Persons with Multiple Chronic Conditions: Embracing Heterogeneity, Causality, and Competing Events. International Journal Of Statistics In Medical Research 2016, 5: 48-55. PMID: 27076862, PMCID: PMC4827855, DOI: 10.6000/1929-6029.2016.05.01.5.Peer-Reviewed Original ResearchMultiple chronic conditionsPatient-centered outcomesPatient reported outcomesAbsolute risk calculationRisk calculatorChronic conditionsMore chronic medical conditionsPopulation of patientsChronic medical conditionsComplex treatment decisionsTreatment effectsPatient characteristicsAbsolute riskReported outcomesTreatment decisionsMedical conditionsPropensity score methodsSpecific treatmentRisk calculationOutcomesCompeting EventsPatientsTreatmentRiskScore method
2015
Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia
Barakat LA, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgün KM, Goetz MB, Butt AA, Rodriguez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia. HIV Medicine 2015, 16: 421-430. PMID: 25959543, PMCID: PMC5015437, DOI: 10.1111/hiv.12244.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaVeterans Aging Cohort StudyVACS IndexCAP outcomesAntiretroviral therapyOlder adultsHigher VACS indexDays of dischargeAging Cohort StudyUninfected participantsCohort studyMean LOSHIV infectionLonger LOSClinical outcomesUnadjusted analysesUninfected groupMultivariable modelEligibility criteriaHIVMale veteransMortality rateART useMortalityOutcomes
2012
A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome.
Lin H, Allore HG, McAvay G, Tinetti ME, Gill TM, Gross CP, Murphy TE. A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome. American Journal Of Public Health 2012, 103: 177-82. PMID: 22515873, PMCID: PMC3518339, DOI: 10.2105/ajph.2011.300458.Peer-Reviewed Original ResearchConceptsHealth outcomesAttributable fraction methodPrecipitating Events ProjectAdverse health outcomesMultiple diseasesAcute episodeNew onsetHeart failureAdverse outcomesRisk factorsAttributable fractionNew Haven CountyDiseaseIndividual diseasesOlder adultsOutcomesAdditive effectDeathEvent outcomesOnsetPneumoniaCohort
2010
Treatment of Death in the Analysis of Longitudinal Studies of Gerontological Outcomes
Murphy TE, Han L, Allore HG, Peduzzi PN, Gill TM, Lin H. Treatment of Death in the Analysis of Longitudinal Studies of Gerontological Outcomes. The Journals Of Gerontology Series A 2010, 66A: 109-114. PMID: 21030467, PMCID: PMC3011957, DOI: 10.1093/gerona/glq188.Peer-Reviewed Original ResearchConceptsFunctional disabilityOlder study populationStudy populationLongitudinal studyOlder personsCommunity-living older personsHealthy survivor effectLongitudinal outcomesSurvivor effectFunctional abilityDeathOutcomesDisabilityLongitudinal modelingTreatmentInformative censoringNoninformative censoringRapid declineStrong relationshipCohortPopulationPersonsStudySurvivorsDecedents
2005
Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromes
Allore HG, Tinettia M, Gill TM, Peduzzi PN. Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromes. Clinical Trials 2005, 2: 13-21. PMID: 16279575, DOI: 10.1191/1740774505cn067oa.Peer-Reviewed Original ResearchConceptsMultifactorial health conditionsModifiable risk factorsMulticomponent interventionRisk factorsGeriatric syndromesHealth conditionsMultifactorial geriatric syndromeOutcomes of interestIntervention trialsClinical trialsClinical concernIntervention componentsInterventionSyndromeDeleterious effectsTrialsOutcomesBlindingFactors