2019
Characteristics of High Cardiovascular Risk in 1.7 Million Chinese Adults.
Lu J, Lu Y, Yang H, Bilige W, Li Y, Schulz W, Masoudi FA, Krumholz HM. Characteristics of High Cardiovascular Risk in 1.7 Million Chinese Adults. Annals Of Internal Medicine 2019, 170: 298-308. PMID: 30776800, DOI: 10.7326/m18-1932.Peer-Reviewed Original ResearchConceptsHigh CVD riskCVD riskHigh riskHigh cardiovascular disease riskCardiovascular risk increasesHigh cardiovascular riskOverall study populationCardiovascular disease riskBody mass indexMultivariable mixed modelsNational Health CommissionAntihypertensive medicationsAspirin useCardiovascular riskCVD screeningMass indexStudy populationChinese adultsHan ethnicityDisease riskStatinsMixed modelsHealth CommissionSocioeconomic statusPopulation subgroups
2018
Screening ECGs in low-risk patients are associated with increased risk of downstream cardiac testing
Mahajan S, Krumholz HM. Screening ECGs in low-risk patients are associated with increased risk of downstream cardiac testing. BMJ Evidence-Based Medicine 2018, 23: 150. PMID: 29674521, DOI: 10.1136/bmjebm-2018-110943.Peer-Reviewed Original Research
2017
Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project)
Lu J, Lu Y, Wang X, Li X, Linderman GC, Wu C, Cheng X, Mu L, Zhang H, Liu J, Su M, Zhao H, Spatz ES, Spertus JA, Masoudi FA, Krumholz HM, Jiang L. Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project). The Lancet 2017, 390: 2549-2558. PMID: 29102084, DOI: 10.1016/s0140-6736(17)32478-9.Peer-Reviewed Original ResearchConceptsControl of hypertensionBlood pressureAntihypertensive medicationsCardiac Events Million Persons ProjectSelf-reported antihypertensive medication usePopulation-based screening studyPopulation-based screening projectMillion Persons ProjectPrescribed antihypertensive medicationsPrevious cardiovascular eventsAntihypertensive medication useDiastolic blood pressureSystolic blood pressureManagement of hypertensionCalcium channel blockersProportion of participantsSelf-reported diagnosisCommunity-dwelling adultsSex-standardised ratesCardiovascular eventsHypertensive adultsMedication classesHypertension awarenessHypertension prevalenceClinical factors
2009
The Utility of Shorter Epochs in Direct Motion Monitoring
Dorsey K, Herrin J, Krumholz H, Irwin M. The Utility of Shorter Epochs in Direct Motion Monitoring. Research Quarterly For Exercise And Sport 2009, 80: 460-468. PMID: 19791632, PMCID: PMC3152374, DOI: 10.1080/02701367.2009.10599584.Peer-Reviewed Original Research
2008
Prevention of Heart Failure
Schocken DD, Benjamin EJ, Fonarow GC, Krumholz HM, Levy D, Mensah GA, Narula J, Shor ES, Young JB, Hong Y. Prevention of Heart Failure. Circulation 2008, 117: 2544-2565. PMID: 18391114, DOI: 10.1161/circulationaha.107.188965.Peer-Reviewed Original ResearchConceptsPrevention of HFChronic kidney diseaseCoronary heart diseaseKidney diseaseHeart diseaseRisk factorsAsymptomatic left ventricular systolic dysfunctionLeft ventricular systolic dysfunctionLeft ventricular systolic functionHF prevention strategiesVentricular systolic dysfunctionVentricular systolic functionHeart failure ratesDevelopment of HFNational awareness campaignGenetic risk factorsEvidence-based managementSystolic dysfunctionSystolic functionHeart failurePatient groupPathophysiological basisPrevention strategiesDiseaseEarly detection
2006
Relation Between Medicare Screening Reimbursement and Stage at Diagnosis for Older Patients With Colon Cancer
Gross CP, Andersen MS, Krumholz HM, McAvay GJ, Proctor D, Tinetti ME. Relation Between Medicare Screening Reimbursement and Stage at Diagnosis for Older Patients With Colon Cancer. JAMA 2006, 296: 2815-2822. PMID: 17179458, DOI: 10.1001/jama.296.23.2815.Peer-Reviewed Original ResearchConceptsProximal colon lesionsColon lesionsMedicare beneficiariesColon cancerColonoscopy useEnd Results-MedicareProportion of patientsUse of colonoscopyEnd Results (SEER) areasMultivariate logistic regressionReimbursement policiesColon cancer screeningColon cancer riskMultivariate Poisson regressionYears of ageReimbursement policy changesSigmoidoscopy useEligible patientsOlder patientsColorectal cancerCancer screeningPrimary diagnosisScreening modalityColon cancer diagnosisCancer riskThe effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening.
Gross CP, McAvay GJ, Krumholz HM, Paltiel AD, Bhasin D, Tinetti ME. The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Annals Of Internal Medicine 2006, 145: 646-53. PMID: 17088577, DOI: 10.7326/0003-4819-145-9-200611070-00006.Peer-Reviewed Original ResearchConceptsChronic illnessColorectal cancerChronic conditionsLife expectancyCancer stageEarly-stage colorectal cancerPopulation-based cancer registriesPatients 67 yearsRetrospective cohort studyStage I cancerAdministrative claims dataChronic condition groupsFinal study sampleYears of ageShort life expectancyCohort studyEffect of agePatient ageI cancerCancer RegistryCancer variesHealthy patientsIndividual patientsMedicare claimsAdministrative claims
2005
A Randomized Outpatient Trial of a Decision-Support Information Technology Tool
Apkon M, Mattera JA, Lin Z, Herrin J, Bradley EH, Carbone M, Holmboe ES, Gross CP, Selter JG, Rich AS, Krumholz HM. A Randomized Outpatient Trial of a Decision-Support Information Technology Tool. JAMA Internal Medicine 2005, 165: 2388-2394. PMID: 16287768, DOI: 10.1001/archinte.165.20.2388.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareAttitude of Health PersonnelCost-Benefit AnalysisDecision Support Systems, ClinicalFemaleFloridaHealth ResourcesHospitals, MilitaryHumansKentuckyMaleMass ScreeningMultivariate AnalysisOutcome and Process Assessment, Health CarePatient SatisfactionPreventive MedicineQuality of Health CareConceptsProvider satisfactionAmbulatory clinic visitsUsual care patientsDays of enrollmentQuality process measuresQuality of careProportion of opportunitiesUsual careClinic visitsOutpatient trialSecondary outcomesPrimary outcomeAcute carePatient satisfactionIntervention groupHealth care opportunitiesPatientsClinical decisionCare opportunitiesPharmacy resourcesPreventive measuresProcess measuresCareMedical resourcesModest improvementDiagnosis, Evaluation, and Treatment of Childhood Obesity in Pediatric Practice
Dorsey KB, Wells C, Krumholz HM, Concato J. Diagnosis, Evaluation, and Treatment of Childhood Obesity in Pediatric Practice. JAMA Pediatrics 2005, 159: 632-638. PMID: 15996996, DOI: 10.1001/archpedi.159.7.632.Peer-Reviewed Original ResearchConceptsBody mass indexRisk of overweightHospital-based clinicsHealth maintenance visitsRate of diagnosisType of treatmentComorbid diseasesMass indexOverweight childrenChildhood obesityMedical recordsTreatment recommendationsHigh burdenPediatric practiceRoutine screeningOverweightClinical practiceMaintenance visitsDiagnosisEncounter notesFormal diagnosisTreatmentChildrenSingle-parent householdsRisk